4,360 research outputs found

    Putting the wood back into our rivers: an experiment in river rehabilitation

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    This paper presents an overview of a project established to assess the effectiveness of woody debris (WD) reintroduction as a river rehabilitation tool. An outline of an experiment is presented that aims to develop and assess the effectiveness of engineered log jams (ELJs) under Australian conditions, and to demonstrate the potential for using a range of ELJs to stabilise a previously de-snagged, high energy gravel-bed channel. Furthermore, the experiment will test the effectiveness of a reach based rehabilitation strategy to increase geomorphic variability and hence habitat diversity. While primarily focusing on the geomorphic and engineering aspects of the rehabilitation strategy, fish and freshwater mussel populations are also being monitored. The project is located within an 1100m reach of the Williams River, NSW. Twenty separate ELJ structures were constructed, incorporating a total of 430 logs placed without any artificial anchoring (e.g., no cabling or imported ballast). A geomorphic control reach was established 3.1 km upstream of the project reach. In the 6 months since the structures were built the study site has experienced 6 flows that have overtopped most structures, 3 of the flows were in excess of the mean annual flood, inundating 19 of the ELJs by 2 - 3 m, and one by 0.5 m. Early results indicate that with the exception of LS4 and LS5, all structures are performing as intended and that the geomorphic variability of the reach has substantially increased

    Impact of Endogenous Bile Salts on the Thermodynamics of Supersaturated Active Pharmaceutical Ingredient Solutions

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    A variety of formulation strategies have been developed to mitigate the inadequate aqueous solubility of certain therapeutic agents. Among these, achieving supersaturation in vivo is a promising approach to improve the extent of oral absorption. Because of the thermodynamic instability of supersaturated solutions, inhibitors are needed to kinetically hinder crystallization. In addition to commonly used polymeric additives, bile salts, naturally present in the gastrointestinal tract, have been shown to exhibit crystallization inhibition properties. However, the impact of bile salts on solution thermodynamics is not well understood, although this knowledge is essential in order to explore the mechanism of crystallization inhibition. To better describe solution thermodynamics in the presence of bile salts, a side-by-side diffusion cell was used to evaluate solute flux for solutions of telaprevir in the absence and presence of the six most abundant bile salts in human intestinal fluid at various solute concentrations; flux measurements provide information about the solute thermodynamic activity and hence can provide an improved measurement of supersaturation in complex solutions. Trihydroxy bile salts had minimal impact on solution phase boundaries as well as solute flux, while micellar dihydroxy bile salts solubilized telaprevir leading to reduced solute flux across the membrane. An inconsistency between the concentration-based supersaturation ratio and that based on solute thermodynamic activity (the fundamental driving force for crystallization) was noted, suggesting that the activity-based supersaturation should be determined to better interpret any modification in crystallization kinetics in the presence of these additives. These findings indicate that bile salts are not interchangeable from a thermodynamic perspective and provide a foundation for further studies evaluating the mechanism of crystallization inhibition

    Indestructibility of Vopenka's Principle

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    We show that Vopenka's Principle and Vopenka cardinals are indestructible under reverse Easton forcing iterations of increasingly directed-closed partial orders, without the need for any preparatory forcing. As a consequence, we are able to prove the relative consistency of these large cardinal axioms with a variety of statements known to be independent of ZFC, such as the generalised continuum hypothesis, the existence of a definable well-order of the universe, and the existence of morasses at many cardinals.Comment: 15 pages, submitted to Israel Journal of Mathematic

    Ariel - Volume 4 Number 2

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    Editors David A. Jacoby Eugenia Miller Tom Williams Associate Editors Paul Bialas Terry Burt Michael Leo Gail Tenikat Editor Emeritus and Business Manager Richard J. Bonnano Movie Editor Robert Breckenridge Staff Richard Blutstein Mary F. Buechler Steve Glinks Len Grasman Alice M. Johnson J. D. Kanofsky Tom Lehman Dave Mayer Bernie Odd

    Deformation of the Planetary Orbits Caused by the Time Dependent Gravitational Potential in the Universe

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    In the paper are studied the deformations of the planetary orbits caused by the time dependent gravitational potential in the universe. It is shown that the orbits are not axially symmetric and the time dependent potential does not cause perihelion precession. It is found a simple formula for the change of the orbit period caused by the time dependent gravitational potential and it is tested for two binary pulsars.Comment: 7 page

    Holographic Coulomb branch vevs

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    We compute holographically the vevs of all chiral primary operators for supergravity solutions corresponding to the Coulomb branch of N=4 SYM and find exact agreement with the corresponding field theory computation. Using the dictionary between 10d geometries and field theory developed to extract these vevs, we propose a gravity dual of a half supersymmetric deformation of N=4 SYM by certain irrelevant operators.Comment: 16 pages, v2 corrections in appendi

    Simulation of Water Cerenkov Detectors Using {\sc geant4}

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    We present a detailed simulation of the performance of water Cerenkov detectors suitable for use in the Pierre Auger Observatory. Using {\sc geant4}, a flexible object-oriented simulation program, including all known physics processes, has been developed. The program also allows interactive visualization, and can easily be modified for any experimental setup.Comment: Talk to be presented at the XI Symposium on Very High Energy Cosmic Ray Interaction

    Correlation functions of small-scale fluctuations of the interplanetary magnetic field

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    The Interplanetary Magnetic Field shows complex spatial and temporal variations. Single spacecraft measurements reveal only a one dimensional section of this rich four dimensional phenomenon. Multi-point measurements of the four Cluster spacecraft provide a unique tool to study the spatiotemporal structure of the field. Using Cluster data we determined three dimensional correlation functions of the fluctuations. By means of the correlation function one can describe and measure field variations. Our results can be used to verify theoretical predictions, to understand the formation and nature of solar wind turbulence. We found that the correlation length varies over almost six orders of magnitude. The IMF turbulence shows significant anisotropy with two distinct populations. In certain time intervals the ratio of the three axes of the correlation ellipse is 1/2.2/6 while in the remaining time we found extremely high correlation along one axis. We found favoured directions in the orientation of the correlation ellipsoids.Comment: accepted to Solar Physics on June 14, 2010. 10 pages, 8 figure
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