Spatial distribution of thermal variables, acoustics and lighting in compost dairy barn with climate control system

ArticleThe main objective of this research was to evaluate the spatial distribution of the thermal variables, acoustics and lighting in climate controlled compost dairy barn. The experiment was conducted in October 2017, in a farm located in the west of Minas Gerais state, Brazil. For the study, the interior of the animal facility was divided into 120 meshes equidistant points, in which air temperature (tdb), relative humidity (RH), noise, illuminance, and air speed (Vair) were manually collected. The technique of geostatistics was used to evaluate the distribution and spatial dependence of variables. Spatial distribution maps showed the occurrence of high variability of attributes and content within the animal facility. Thermal environment variables showed alert situations throughout practically the entire facility. The noise and luminance levels were within the recommended values

Evaluation of cardiovascular risk factors in the Wistar Audiogenic Rat (WAR) Strain

Introduction: Risk factors for life-threatening cardiovascular events were evaluated in an experimental model of epilepsy, the Wistar Audiogenic Rat (WAR) strain. Methods: We used long-term ECG recordings in conscious, one year old, WAR and Wistar control counterparts to evaluate spontaneous arrhythmias and heart rate variability, a tool to assess autonomic cardiac control. Ventricular function was also evaluated using the pressure-volume conductance system in anesthetized rats. Results: Basal RR interval (RRi) was similar between WAR and Wistar rats (188\ub15 vs 199\ub16 ms). RRi variability strongly suggests that WAR present an autonomic imbalance with sympathetic overactivity, which is an isolated risk factor for cardiovascular events. Anesthetized WAR showed lower arterial pressure (92\ub13 vs 115\ub15 mmHg) and exhibited indices of systolic dysfunction, such as higher ventricle end-diastolic pressure (9.2\ub10.6 vs 5.6\ub11 mmHg) and volume (137\ub19 vs 68\ub19 \u3bcL) as well as lower rate of increase in ventricular pressure (5266\ub1602 vs 7320\ub1538 mmHg.s-1). Indices of diastolic cardiac function, such as lower rate of decrease in ventricular pressure (-5014\ub1780 vs -7766\ub1998 mmHg.s-1) and a higher slope of the linear relationship between end-diastolic pressure and volume (0.078\ub10.011 vs 0.036\ub10.011 mmHg.\u3bcL), were also found in WAR as compared to Wistar control rats. Moreover, Wistar rats had 3 to 6 ventricular ectopic beats, whereas WAR showed 15 to 30 ectopic beats out of the 20,000 beats analyzed in each rat. Conclusions: The autonomic imbalance observed previously at younger age is also present in aged WAR and, additionally, a cardiac dysfunction was also observed in the rats. These findings make this experimental model of epilepsy a valuable tool to study risk factors for cardiovascular events in epilepsy

Consumption of medicines in high-risk pregnancy: evaluation of determinants related to the use of prescription drugs and self-medication

The use of drugs during pregnancy still represents a challenge for medicine, since the majority of drugs cross the placental barrier with a potential to cause several congenital problems to the fetus, and most of them have not been clinically tested in pregnant patients. At the same time, the medicalization phenomenon, self-medication, and lack of patient information about the misuse of medicines are additional problems. Thus, the aim of this study was to evaluate the pattern of medicine consumption in high-risk pregnancies and the determinants related to this consumption pattern. In order to do so, a cross-sectional descriptive study was performed with puerperal women who had a history of high-risk pregnancy. Statistically significant associations were found between self-medication and fewer prenatal visits, and cigarette use during pregnancy and a higher number of children. According to these data, the vulnerability of this population to the risks of drug use is evident, demonstrating a gap that requires urgent interventions in health-care education