Use of accelerometry to investigate physical activity in dogs receiving chemotherapy

Objectives: To perform a preliminary study to assess whether single-agent palliative or adjuvant chemotherapy has an impact on objectively measured physical activity in dogs. Methods: Fifteen dogs with neoplasia (treatment group) wore ActiGraph™ accelerometers for 5-day periods before, during and after receiving single-agent adjuvant or palliative chemotherapy. Mean 5-day total physical activity and time spent in three different intensities of activity (sedentary, light-moderate and vigorous) before, during and after receiving chemotherapy were compared to a group of 15 healthy dogs (control group). Results were also compared within the treatment group across time. Results: Prior to chemotherapy, treated dogs tended to be less active than control dogs. Treatment group dogs were slightly more active at restaging than they were prior to treatment but had similar activity levels to control dogs. Marked effects of chemotherapy on physical activity were not detected. Physical activity was slightly lower in treated dogs during chemotherapy when compared to control dogs but there was a slight increase in physical activity of treated dogs during chemotherapy when compared with pretreatment recordings. There was little change in the mean 5-day total physical activity between treated dogs during chemotherapy and at restaging but a mild decrease in time spent sedentary and increase in time spent in light-moderate activity at this comparison of time points. Clinical Significance: Single-agent adjuvant or palliative chemotherapy had minimal impact on physical activity levels in dogs with neoplasia

Pulsation in carbon-atmosphere white dwarfs: A new chapter in white dwarf asteroseismology

We present some of the results of a survey aimed at exploring the asteroseismological potential of the newly-discovered carbon-atmosphere white dwarfs. We show that, in certains regions of parameter space, carbon-atmosphere white dwarfs may drive low-order gravity modes. We demonstrate that our theoretical results are consistent with the recent exciting discovery of luminosity variations in SDSS J1426+5752 and some null results obtained by a team of scientists at McDonald Observatory. We also present follow-up photometric observations carried out by ourselves at the Mount Bigelow 1.6-m telescope using the new Mont4K camera. The results of follow-up spectroscopic observations at the MMT are also briefly reported, including the surprising discovery that SDSS J1426+5752 is not only a pulsating star but that it is also a magnetic white dwarf with a surface field near 1.2 MG. The discovery of $g$-mode pulsations in SDSS J1426+5752 is quite significant in itself as it opens a fourth asteroseismological "window", after the GW Vir, V777 Her, and ZZ Ceti families, through which one may study white dwarfs.Comment: 7 pages, 4 figures, to appear in Journal of Physics Conference Proceedings for the 16th European White Dwarf Worksho

Studies of hot B subdwarfs. Part 2: Energy distributions of three bright sdB/sdOB stars in the 950-5500 angstrom range

Voyager ultraviolet spectrometer observations of the subdwarf B or OB stars HD 205805, UV 1758+36 and Feige 66 are presented. All three objects display the H I Layman series in absorption. These observations are combined with low dispersion IUE spectrophotometry and with Stroemgren photometry to construct virtually complete energy distributions, which extend over the range 950-5500 angstroms. Effective temperatures based on model atmosphere calculations for high gravity, hydrogen rich stars are determined. Our analyses yield T Sub e 28,200 + or - 1300 K for HD 205805, T sub e 31, 800 + or - 1100 K for UV 1758+36, and T sub e 35,700 + or - 1500 K for Feige 66. The importance of far ultraviolet observations below L sub alpha in reducing the uncertainties associated with the interstellar extinction and the degradation of the IUE sensitivity is emphasized

Radiative levitation: a likely explanation for pulsations in the unique hot O subdwarf star SDSS J160043.6+074802.9

Context. SDSS J160043.6+074802.9 (J1600+0748 for short) is the only hot sdO star for which unambiguous multiperiodic luminosity variations have been reported so far. These rapid variations, with periods in the range from ~60 s to ~120 s, are best qualitatively explained in terms of pulsational instabilities, but the exact nature of the driving mechanism has remained a puzzle. Aims. Our primary goal is to examine quantitatively how pulsation modes can be excited in an object such as J1600+0748. Given the failure of uniform-metallicity models as well documented in the recent Ph.D. thesis of C. Rodríguez-López, we consider the effects of radiative levitation on iron as a means to boost the efficiency of the opacity-driving mechanism in models of J1600+0748. Methods. We combine high sensitivity time-averaged optical spectroscopy and full nonadiabatic calculations to carry out our study. In the first instance, this is used to estimate the location of J1600+0748 in the log $g-T_{\rm eff}$ plane. Given this essential input, we pulsate stellar models consistent with these atmospheric parameters. We construct both uniform-metallicity models and structures in which the iron abundance is specified by the condition of diffusive equilibrium between gravitational settling and radiative levitation. Results. On the basis of NTLE H/He synthetic spectra, we find that the target star has the following atmospheric parameters: log g = 5.93 $\pm$ 0.11, $T_{\rm eff}$ = 71 070 $\pm$ 2725 K, and log N(He)/N(H) = -0.85 $\pm$ 0.08. This takes into account our deconvolution of the spectrum of J1600+0748 as it is polluted by the light of a main sequence companion. We confirm that uniform-metallicity stellar models with Z in the range from 0.02 to 0.10 cannot excite pulsation modes of the kind observed. On the other hand, we find that the inclusion of radiative levitation, as we implemented it, leads to pulsational instabilities in a period range that overlaps with, although it is narrower than, the observed range in J1600+0748. The excited modes correspond to low-order, low-degree p-modes. Conclusions. We infer that radiative levitation is a likely essential ingredient in the excitation physics at work in J1600+0748

A NLTE model atmosphere analysis of the pulsating sdO star SDSS J1600+0748

We started a program to construct several grids of suitable model atmospheres and synthetic spectra for hot subdwarf O stars computed, for comparative purposes, in LTE, NLTE, with and without metals. For the moment, we use our grids to perform fits on our spectrum of SDSS J160043.6+074802.9 (J1600+0748 for short), this unique pulsating sdO star. Our best fit is currently obtained with NLTE model atmospheres including carbon, nitrogen and oxygen in solar abundances, which leads to the following parameters for SDSS J1600+0748 : Teff = 69 060 +/- 2080 K, log g = 6.00 +/- 0.09 and log N(He)/N(H) = -0.61 +/- 0.06. Improvements are needed, however, particularly for fitting the available He II lines. It is hoped that the inclusion of Fe will help remedy the situation.Comment: 4 pages, 4 figures, accepted in Astrophysics and Space Science (24/02/2010), Special issue Hot sudbwarf star

On a Conjecture of Rapoport and Zink

In their book Rapoport and Zink constructed rigid analytic period spaces $F^{wa}$ for Fontaine's filtered isocrystals, and period morphisms from PEL moduli spaces of $p$-divisible groups to some of these period spaces. They conjectured the existence of an \'etale bijective morphism $F^a \to F^{wa}$ of rigid analytic spaces and of a universal local system of $Q_p$-vector spaces on $F^a$. For Hodge-Tate weights $n-1$ and $n$ we construct in this article an intrinsic Berkovich open subspace $F^0$ of $F^{wa}$ and the universal local system on $F^0$. We conjecture that the rigid-analytic space associated with $F^0$ is the maximal possible $F^a$, and that $F^0$ is connected. We give evidence for these conjectures and we show that for those period spaces possessing PEL period morphisms, $F^0$ equals the image of the period morphism. Then our local system is the rational Tate module of the universal $p$-divisible group and enjoys additional functoriality properties. We show that only in exceptional cases $F^0$ equals all of $F^{wa}$ and when the Shimura group is $GL_n$ we determine all these cases.Comment: v2: 48 pages; many new results added, v3: final version that will appear in Inventiones Mathematica

Just how hot are the ω\omega Centauri extreme horizontal branch pulsators?

Past studies based on optical spectroscopy suggest that the five $\omega$ Cen pulsators form a rather homogeneous group of hydrogen-rich subdwarf O stars with effective temperatures of around 50 000 K. This places the stars below the red edge of the theoretical instability strip in the log $g$ $-$ Teff diagram, where no pulsation modes are predicted to be excited. Our goal is to determine whether this temperature discrepancy is real, or whether the stars' effective temperatures were simply underestimated. We present a spectral analysis of two rapidly pulsating extreme horizontal branch (EHB) stars found in $\omega$ Cen. We obtained Hubble Space Telescope/COS UV spectra of two $\omega$ Cen pulsators, V1 and V5, and used the ionisation equilibrium of UV metallic lines to better constrain their effective temperatures. As a by-product we also obtained FUV lightcurves of the two pulsators. Using the relative strength of the N IV and N V lines as a temperature indicator yields Teff values close to 60 000 K, significantly hotter than the temperatures previously derived. From the FUV light curves we were able to confirm the main pulsation periods known from optical data. With the UV spectra indicating higher effective temperatures than previously assumed, the sdO stars would now be found within the predicted instability strip. Such higher temperatures also provide consistent spectroscopic masses for both the cool and hot EHB stars of our previously studied sample.Comment: 9 pages, accepted for publication in Astronomy and Astrophysic

Kepler detection of a new extreme planetary system orbiting the subdwarf-B pulsator KIC10001893

KIC10001893 is one out of 19 subdwarf-B (sdB) pulsators observed by the Kepler spacecraft in its primary mission. In addition to tens of pulsation frequencies in the g-mode domain, its Fourier spectrum shows three weak peaks at very low frequencies, which is too low to be explained in terms of g modes. The most convincing explanation is that we are seeing the orbital modulation of three Earth-size planets (or planetary remnants) in very tight orbits, which are illuminated by the strong stellar radiation. The orbital periods are P1=5.273, P2=7.807, and P3=19.48 hours, and the period ratios P2/P1=1.481 and P3/P2=2.495 are very close to the 3:2 and 5:2 resonances, respectively. One of the main pulsation modes of the star at 210.68 {\mu}Hz corresponds to the third harmonic of the orbital frequency of the inner planet, suggesting that we see, for the first time in an sdB star, g-mode pulsations tidally excited by a planetary companion. The extreme planetary system that emerges from the Kepler data is very similar to the recent discovery of two Earth-size planets orbiting the sdB pulsator KIC05807616 (Charpinet et al. 2011a).Comment: 6 pages, 5 figures, accepted for publication in Astronomy and Astrophysic