Effects of electrode configuration and geometry on fiber preference in spinal cord stimulation

In contrast to the widespread assumption that dorsal column fibers are the primary targets of spinal cord stimulation by a dorsal epidural electrode, it appears that dorsal root fibers are recruited as well, and even preferentially under various conditions. This will, however, limit the coverage of the painful body areas with paresthesia, a prerequisite for the management of chronic pain. In order to favor the preferential stimulation of dorsal column fibers, advantage was taken of the different positions and orientations of fibers in the dorsal columns and dorsal roots. Using an SCS computer model, electrode configurations have been designed for the selective stimulation of the human dorsal column

John W. Reed

A tribute to John W. Ree

The Cowan Adolescent Adjustment Analyzer Used As An Instrument For The Evaluation of Academic Functional Efficiency.

The development of The Cowan Adolescent Adjustment Analyzer, an Instrument of Clinical Psychology, was the product of more than twenty-five years of study by its original author, the late Dr. Edwina Abbott Cowan. This study is a further contribution to needed research to enhance an already accepted instrument of clinic al psychology. The area of major emphasis in the present study is academic functional efficiency. To this has been added, however, some significant data relating to the comparison of the Analyzer s cores to I. Q. scores and a comparison of the score s of students in early adolescence with those in middle or late adolescence

Alien Registration- Dumont, Wilbert J. (Island Falls, Aroostook County)

https://digitalmaine.com/alien_docs/34880/thumbnail.jp

Real Springer fibers and odd arc algebras

We give a topological description of the two-row Springer fiber over the real numbers. We show its cohomology ring coincides with the oddification of the cohomology ring of the complex Springer fiber introduced by Lauda-Russell. We also realize Ozsv\'ath-Rasmussen-Szab\'o odd TQFT from pullbacks and exceptional pushforwards along inclusion and projection maps between hypertori. Using these results, we construct the odd arc algebra as a convolution algebra over components of the real Springer fiber, giving an odd analogue of a construction of Stroppel-Webster

The Effect of the Pendency of Claims for Compensation Upon Behavior Indicative of Pain

Recent theories endeavoring to explain manifestations of pain in humans have increasingly recognized the effect of sociological and psychological processes on pain.This article reports findings made in a research project based on the hypothesis that the pendency of a claim for compensation has the effect of causing greater, more intense, and more persistent pain than would otherwise be experienced if persons had not sought compensation. The study assumed that pain can most accurately be measured by observing behavior indicative of pain and focused on data reflecting such behavior. The lawyer-author of this article thought the study might demonstrate that current compensation practices are a significant cause of pain behavior, and anticipated that such a finding could lead to revision of claims procedures or even changes in methods of compensation. The project revealed, however, no significant effects of either litigation or representation by attorneys upon the pain behavior of persons having workmen\u27s compensation claims with the Department of Labor and Industries of the State of Washington

Identification of a Chitin-Binding Protein Secreted by Pseudomonas aeruginosa

One of the major proteins secreted by Pseudomonas aeruginosa is a 43-kDa protein, which is cleaved by elastase into smaller fragments, including a 30-kDa and a 23-kDa fragment. The N-terminal 23-kDa fragment was previously suggested as corresponding to a staphylolytic protease and was designated LasD (S. Park and D. R. Galloway, Mol. Microbiol. 16:263-270, 1995). However, the sequence of the gene encoding this 43-kDa protein revealed that the N-terminal half of the protein is homologous to the chitin-binding proteins CHB1 of Streptomyces olivaceoviridis and CBP21 of Serratia marcescens and to the cellulose-binding protein p40 of Streptomyces halstedii. Furthermore, a short C-terminal fragment shows homology to a part of chitinase A of Vibrio harveyi. The full-length 43-kDa protein could bind chitin and was thereby protected against the proteolytic activity of elastase, whereas the degradation products did not bind chitin. The purified 43-kDa chitin-binding protein had no staphylolytic activity, and comparison of the enzymatic activities in the extracellular medium of a wild-type strain and a chitin-binding protein-deficient mutant indicated that the 43-kDa protein supports neither chitinolytic nor staphylolytic activity. We conclude that the 43-kDa protein, which was found to be produced by many clinical isolates of P. aeruginosa, is a chitin-binding protein, and we propose to name it CbpD (chitin-binding protein D)

Cognitive skills and their transfer: Discussion

Transfer is involved in all learning, remembering, problem solving and cognitive activities. Thus we need to think of dimensions and extent of transfer rather than simply consider transfer versus non-transfer. Moreover, we should consider transfer of motivation as well as transfer of learned cognitions if we are to understand transfer of learning in educational situations and be helpful to educators. Metacognitive, as well as cognitive, strategies are useful in facilitating transfer in many situations even though they may overload or interfere with transfer in situations where automatized responses are appropriate. We need research to determine when metacognition should be called into play. Research is also needed on the interaction of cognitive and motivational variables affecting transfer.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/26983/1/0000550.pd

Effects of unregulated international fishing on recovery potential of the sandbar shark within the southeast United States

Coastal sharks are challenging to manage in the United States due to their slow life history, limited data availability, history of overexploitation, and competing stakeholder interests. Furthermore, species like the sandbar shark are subjected to international exploitation unmanaged by the U.S. We conducted a management strategy evaluation using Stock Synthesis on the sandbar shark to test the performance of various configurations of a threshold harvest control rule. In addition to uncertainties addressed in the operating model, we built multiple implementation models to address uncertainties related to future levels of a partially unmanaged source of removals, the combined Mexican and U.S. recreational (MexRec) fleet. We found that the presence of unregulated removals had the potential to significantly influence the success of the various management procedures tested. Notably, if MexRec catches continue to increase with total stock abundance following historical trends, the rate of MexRec removals will be too large to allow the sandbar shark to recover across operating models. We present trade-offs between performance metrics across a range of 24 management procedures and three implementation models