A gain-coefficient switched Alexandrite laser

We report on a gain-coefficient switched Alexandrite laser. An electro-optic modulator is used to switch between high and low gain states by making use of the polarization dependent gain of Alexandrite. In gain-coefficient switched mode, the laser produces 85 ns pulses with a pulse energy of 240 mJ at a repetition rate of 5 Hz.Comment: 8 pages, 5 figure

Mapping individual electromagnetic field components inside a photonic crystal

We present a method to map the absolute electromagnetic field strength inside photonic crystals. We apply the method to map the electric field component Ez of a two-dimensional photonic crystal slab at microwave frequencies. The slab is placed between two mirrors to select Bloch standing waves and a subwavelength spherical scatterer is scanned inside the resulting resonator. The resonant Bloch frequencies shift depending on the electric field at the position of the scatterer. To map the electric field component Ez we measure the frequency shift in the reflection and transmission spectrum of the slab versus the scatterer position. Very good agreement is found between measurements and calculations without any adjustable parameters.Comment: 12 pages, 7 figure

Robust zero-energy modes in an electronic higher-order topological insulator: the dimerized Kagome lattice

Quantum simulators are an essential tool for understanding complex quantum materials. Platforms based on ultracold atoms in optical lattices and photonic devices led the field so far, but electronic quantum simulators are proving to be equally relevant. Simulating topological states of matter is one of the holy grails in the field. Here, we experimentally realize a higher-order electronic topological insulator (HOTI). Specifically, we create a dimerized Kagome lattice by manipulating carbon-monoxide (CO) molecules on a Cu(111) surface using a scanning tunneling microscope (STM). We engineer alternating weak and strong bonds to show that a topological state emerges at the corner of the non-trivial configuration, while it is absent in the trivial one. Contrarily to conventional topological insulators (TIs), the topological state has two dimensions less than the bulk, denoting a HOTI. The corner mode is protected by a generalized chiral symmetry, which leads to a particular robustness against perturbations. Our versatile approach to quantum simulation with artificial lattices holds promises of revealing unexpected quantum phases of matter

[An implant-supported overdenture in an edentulous upper jaw].

An implant-supported overdenture is a good alternative treatment to a conventional denture for patients with complaints about the retention and stability of their removable complete denture. These complaints more often have to do with the mandibular than the maxillary denture. Implant-supported overdentures offer better results in the mandible than in the maxilla. In cases of insujficient bone volume in the maxilla for inserting implants, maxillary sinus floor elevation using an autogenous bone graft from the oral cavity or the iliac crest may be carried out. Treatment of the edentulous maxilla by inserting 6 implants followed by manufacturing a bar-clip mesostructure and an implant-supported overdenture is the most successful, followed closely by the treatment option of inserting 4 implants and fabricating a similar mesostructure and overdenture. Aftercare by routine preventive examinations is required.</p

Vesicular Tubular Clusters between the ER and Golgi Mediate Concentration of Soluble Secretory Proteins by Exclusion from COPI-Coated Vesicles

AbstractWe have determined the concentrations of the secretory proteins amylase and chymotrypsinogen and the membrane proteins KDELr and rBet1 in COPII- and COPI-coated pre-Golgi compartments of pancreatic cells by quantitative immunoelectron microscopy. COPII was confined to ER membrane buds and adjacent vesicles. COPI occurred on vesicular tubular clusters (VTCs), Golgi cisternae, the trans-Golgi network, and immature secretory granules. Both secretory proteins exhibited a first, significant concentration step in noncoated segments of VTC tubules and were excluded from COPI-coated tips. By contrast, KDELr and rBet1 showed a first, significant concentration in COPII-coated ER buds and vesicles and were prominently present in COPI-coated tips of VTC tubules. These data suggest an important role of VTCs in soluble cargo concentration by exclusion from COPI-coated domains

Prosthetic dilemmas. Choice of superstructure for the edentulous maxilla

Patients with an edentulous maxilla can experience problems with a full upper denture. The most common problems are a lack of retention and the stability of the denture, but also other factors, such as an extreme gagging reflex, influence satisfaction. Attachment of a prosthesis on dental implants is a reliable solution to solve or diminish the above mentioned problems. The choice of the kind of superstructure, a removable overdenture or a fixed prosthesis, depends on a variety of factors, such as degree of resorption of the maxilla, cleaning possibilities, patients'wishes and financial possibilities</p

Prosthetic dilemmas. Choice of superstructure for the edentulous maxilla

Patients with an edentulous maxilla can experience problems with a full upper denture. The most common problems are a lack of retention and the stability of the denture, but also other factors, such as an extreme gagging reflex, influence satisfaction. Attachment of a prosthesis on dental implants is a reliable solution to solve or diminish the above mentioned problems. The choice of the kind of superstructure, a removable overdenture or a fixed prosthesis, depends on a variety of factors, such as degree of resorption of the maxilla, cleaning possibilities, patients'wishes and financial possibilities</p