Locally advanced adenocarcinoma of the rectum presenting with necrotising fasciitis of the perineum: successful management with early aggressive surgery and multimodal therapy

Colorectal cancer is a common malignant neoplasm and its treatment usually involves surgery associated, in some cases, depending on the staging, with chemoradiotherapy. Necrotising fasciitis of the perineum is a highly lethal infection of the perineum, perirectal tissues and genitals, requiring emergency surgical debridement, broad-spectrum antibiotics and control of sepsis. We present the case of a 59-year-old man with necrotising fasciitis of the perineum as the first clinical manifestation of locally advanced adenocarcinoma of the rectum, in which successful management consisted of early and aggressive surgical debridement, followed by multimodal therapy with curative intent. 2 years and 6 months after surgery the patient is well, with no evidence of local or systemic relapse.info:eu-repo/semantics/publishedVersio

Mortars with incorporation of PCM based in different binders: mechanical and thermal behavior

Currently we are witnessing a huge concern of society with the parameters of comfort of the buildings and the energetic consumptions. It is known that there is a huge consumption of non-renewable sources of energy. Thus, it is urgent to develop and explore ways to take advantage of renewable sources of energy by improving the energy efficiency of buildings. The mortars with incorporation of phase change materials (PCM) have the ability to regulate the temperature inside buildings, contributing to the thermal comfort and reduction of the use of heating and cooling equipment, using only the energy supplied by the sun. However, the incorporation of phase change materials in mortars modifies its characteristics. The main purpose of this study was mechanical and thermal characterization of mortars with incorporation of PCM in mortars based in different binders. The binders studied were aerial lime, hydraulic lime, gypsum and cement. For each type of binder a reference composition (0% PCM) and a composition with incorporation of 40% of PCM were developed. It was possible to observe that the incorporation of PCM in mortars caused differences in properties such as workability, compressive strength, flexural strength and adhesion, however leads to an improvement of thermal behavior.Foundation for Science and Technology(FCT

Sustainable mortars with incorporation of microencapsulated phase change materials

The construction industry is responsible for high energy and raw materials consumption. Thus, it is important to minimize the high energy consumption by taking advantage of renewable energy sources and reusing industrial waste, decreasing the extraction of natural materials. The mortars with incorporation of phase change materials (PCM) have the ability to regulate the temperature inside buildings, contributing to the thermal comfort and reduction of the use of heating and cooling equipment, using only the energy supplied by the sun. The simultaneous incorporation of PCM and fly ash (FA) can reduce the energy consumption and the amount of materials landfilled. However, the addition of these materials in mortars modifies its characteristics. The main purpose of this study was the production and characterization in the fresh and hardened state of mortars with incorporation of different contents of PCM and FA. The binders studied were aerial lime, hydraulic lime, gypsum and cement. The proportion of PCM studied was 0%, 20%, 40% and 60% of the mass of the sand. The content of fly ash added to the mortars was 0%, 20%, 40% and 60% of the mass of the binder. It was possible to observe that the incorporation of PCM and fly ash in mortars caused differences in properties such as workability, microstructure, water absorption, compressive strength, flexural strength and adhesion

Precision agriculture trends in fruit growing from 2016 to 2020.

Brazilian fruit culture has a great influence on the social and economic sector in the most diverse regions of the country, generating employment and income in the exercise of its activities. As it is an activity carried out most often in a manual and conventional manner, fruit culture has a great potential for technological growth, especially when adopting the concepts applied by precision agriculture on the crops of grains, fibers and energy, creating a new segment, Precision Fruit Farming. The present work aims to carry out a bibliographic review on the main trends that have emerged in the last five years on Precision Fruit growing, highlighting its future perspectives and the history of technological evolution. 83 articles were analyzed, classified in different perennial cultures and applications, such as machine learning, remote sensing, robotics, using UAV to obtain different vegetation indexes, among others. Index Terms: Machine Learning; Vegetation Indexes; Robotics; Tendências da agricultura de precisão em fruticultura no período de 2016 A 2020 Resumo - A fruticultura brasileira exerce grande influência sobre o setor social e econômico nas mais diversas regiões do País, gerando emprego e renda no exercício de suas atividades. Por se tratar de uma atividade realizada, na maioria das vezes, de forma manual e convencional, a fruticultura possui grande potencial de crescimento tecnológico, principalmente ao adotar os conceitos aplicados pela agricultura de precisão sobre as culturas de grãos, fibras e energia, criando um novo segmento, a Fruticultura de Precisão. O presente estudo objetivou realizar uma revisão bibliográfica sobre as principais tendências que surgiram nos últimos cinco anos sobre a Fruticultura de Precisão, destacando suas perspectivas futuras e o histórico de evolução tecnológica. Foram analisados 83 artigos, classificados em diferentes culturas perenes e aplicações, como machine learning (aprendizado de máquinas), sensoriamento remoto, robótica, utilização de VANT para obtenção de diferentes índices de vegetação, entre outras. Termos para indexação: Aprendizagem de Máquina; Índices de Vegetação; Robótica; Sensoriamento Remoto; VANT

Chemical characterization and evaluation of the microbiological quality of juçaí pulp (Euterpe edulis) native to the state of Rio de Janeiro.

The juçara palm (Euterpe edulis), endemic to the Atlantic forest region, is known for producing a palm heart known for producing an excellent quality of palm heart and its extractive exploitation led to the exhaustion of the species in the natural reserves. Its fruit, juçaí, has an organoleptic, nutritional and commercial potential similar to the açaí (Euterpe oleracea), native to the Amazon region, besides representing a sustainable alternative of preservation of the species.SLACA, 12. De 4 a 7 de Novembro de 2017. Ref. 71796

sensitivity analysis

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Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas

Germinal mutations in the base excision repair (BER) gene MUTYH (MYH) have recently been described in association with predisposition to multiple colorectal adenomas and cancer. In contrast to the classic dominant condition of familial adenomatous polyposis (FAP) due to germinal mutations in the APC gene, the MYH polyposis is an autosomal recessive disease. The identification of individuals affected by MYH polyposis brings new and important implications for the diagnostic, screening, genetic counseling, follow up and therapeutic options in these patients. In this study, screening for germinal mutations in the MYH gene was performed in 53 Portuguese individuals with multiple colorectal adenomas or classic adenomatous polyposis, in whom no mutation had been identified in the APC gene. The results revealed the presence of biallelic germline MYH mutations in 21 patients. In addition, we here report 3 mutations (c.340T>C [p.Y114H]; c.503G>A [p.R168H]; and c.1186_1187insGG [p.E396fsX437]) which, to our knowledge, have not been previously describe

State of the Art and Future Challenges in Multiple Sclerosis Research and Medical Management: An Insight into the 5th International Porto Congress of Multiple Sclerosis

The 5th International Porto Congress of Multiple Sclerosis took place between the 14th and 16th of February 2019 in Porto, Portugal. Its intensive programme covered a wide-range of themes—including many of the hot topics, challenges, pitfalls and yet unmet needs in the field of multiple sclerosis (MS)—led by a number of well-acknowledged world experts. This meeting review summarizes the talks that took place during the congress, which focussed on issues in MS as diverse as the development and challenges of progressive MS, epidemiology, differential diagnosis, medical management, molecular research and imaging tools