Experimental investigation of a coherent quantum measurement of the degree of polarization of a single mode light beam

A novel method for the direct measurement of the degree of polarization is described. It is one of the first practical implementations of a coherent quantum measurement, the projection on the singlet state. Our first results demonstrate the successful operation of the method. However, due to the nonlinear crystals used presently, its application is limited to spectral widths larger than ~8nm.Comment: 23 pages, 9 figures, submitted to Journal of Modern Optic

Quantum key distribution with "dual detectors"

To improve the performance of a quantum key distribution (QKD) system, high speed, low dark count single photon detectors (or low noise homodyne detectors) are required. However, in practice, a fast detector is usually noisy. Here, we propose a "dual detectors" method to improve the performance of a practical QKD system with realistic detectors: the legitimate receiver randomly uses either a fast (but noisy) detector or a quiet (but slow) detector to measure the incoming quantum signals. The measurement results from the quiet detector can be used to bound eavesdropper's information, while the measurement results from the fast detector are used to generate secure key. We apply this idea to various QKD protocols. Simulation results demonstrate significant improvements in both BB84 protocol with ideal single photon source and Gaussian-modulated coherent states (GMCS) protocol; while for decoy-state BB84 protocol with weak coherent source, the improvement is moderate. We also discuss various practical issues in implementing the "dual detectors" scheme.Comment: 22 pages, 9 figure

Experimental quantum tossing of a single coin

The cryptographic protocol of coin tossing consists of two parties, Alice and Bob, that do not trust each other, but want to generate a random bit. If the parties use a classical communication channel and have unlimited computational resources, one of them can always cheat perfectly. Here we analyze in detail how the performance of a quantum coin tossing experiment should be compared to classical protocols, taking into account the inevitable experimental imperfections. We then report an all-optical fiber experiment in which a single coin is tossed whose randomness is higher than achievable by any classical protocol and present some easily realisable cheating strategies by Alice and Bob.Comment: 13 page

Demonstration of In Silico docking at a large scale on grid infrastructure

présenté par N. Jac

Grid enabled virtual screening against malaria

34 pages, 5 figures, 3 tables, to appear in Journal of Grid Computing - PCSV, à paraître dans Journal of Grid ComputingWISDOM is an international initiative to enable a virtual screening pipeline on a grid infrastructure. Its first attempt was to deploy large scale in silico docking on a public grid infrastructure. Protein-ligand docking is about computing the binding energy of a protein target to a library of potential drugs using a scoring algorithm. Previous deployments were either limited to one cluster, to grids of clusters in the tightly protected environment of a pharmaceutical laboratory or to pervasive grids. The first large scale docking experiment ran on the EGEE grid production service from 11 July 2005 to 19 August 2005 against targets relevant to research on malaria and saw over 41 million compounds docked for the equivalent of 80 years of CPU time. Up to 1,700 computers were simultaneously used in 15 countries around the world. Issues related to the deployment and the monitoring of the in silico docking experiment as well as experience with grid operation and services are reported in the paper. The main problem encountered for such a large scale deployment was the grid infrastructure stability. Although the overall success rate was above 80%, a lot of monitoring and supervision was still required at the application level to resubmit the jobs that failed. But the experiment demonstrated how grid infrastructures have a tremendous capacity to mobilize very large CPU resources for well targeted goals during a significant period of time. This success leads to a second computing challenge targeting Avian Flu neuraminidase N1

g-INFO portal: a solution to monitor Influenza A on the Grid for non-grid users

International audienceIn this paper, we introduce a portal for monitoring Influenza A on a grid-based system. Influenza A keeps on being a major threat to public health worldwide; especially if one virus can mutate itself so that it acquires the capacity for human to human transmission of H1N1 as well as the high death rate of H5N1. The existing g-INFO (Grid-based Information Network for Flu Observation) project provides a complete system for monitoring flu virus on the Grid. We present here a portal that operates on top of the g-INFO system as a solution for non-grid users to utilize grid services for analyzing molecular biology data of Influenza A

HOPE, an open platform for medical data management on the grid

International audienc

Illusory movements prevent cortical disruption caused by immobilization

International audienceEnforced limb disuse strongly disrupts the cortical networks that are involved in sensorimotor activities. This disruption causes a cortical reorganization that may be functionally maladaptive. In this study, we used functional magnetic resonance imaging (fMRI) to investigate whether it is possible to prevent this reorganization by compensating for the lack of actual kinesthetic perception with illusory movements induced by ``neuromimetic'' proprio-tactile feedback that is artificially delivered during immobilization. Sixteen healthy volunteers were equipped for five days with full-hand ortheses that prevented them from performing finger and hand movements but allowed for kinesthetic and tactile sensations. Eight participants received a twice-daily proprio-tactile treatment consisting of the perception of kinesthetic sensations resembling those felt during actual movements generated by miniature vibrators set in the ortheses at the finger and wrist levels. Eight untreated participants received no stimulation. The effects of hand immobilization and treatment were assessed by fMRI during a calibrated voluntary hand movement task and hand tactile stimulation before cast placement and immediately after cast removal. We found that the sensorimotor network was preserved in subjects who underwent this treatment during hand immobilization, while the sensorimotor network of untreated subjects was significantly altered. These findings suggest that sensory feedback and associated movement perception may counteract disuse-induced cortical plastic changes through recruitment of a large part of the cortical network used for actual performed movement. The possibility of guiding cortical plasticity with proprioceptive augmented feedback is potentially relevant for rehabilitation efforts. (C) 2012 Elsevier Inc. All rights reserved