Responding to Cross Border Child Trafficking in South Asia: An Analysis of the Feasibility of a Technologically Enabled Missing Child Alert System

This report examines the feasibility of a technologically enabled system to help respond to the phenomenon of cross-border child trafficking in South Asia, and makes recommendations on how to proceed with a pilot project in the selected areas of Bangladesh, Nepal and India. The study was commissioned by the Missing Child Alert (MCA) programme which is an initiative led by Plan. MCA is an initiative to address cross-border child trafficking in South Asia, led by Plan. The aim of the programme is to link existing institutions, mechanisms and resources in order to tackle the phenomenon from a regional perspective. To achieve this, Plan propose to implement a technologically equipped, institutionalised system of alert that can assist in the rescue, rehabilitation, repatriation and reintegration of children who are at risk of, or are victims of, cross-border trafficking

Enlargement of Cavernous Haemangioma associated with exogenous administration of oestrogens

A cavernous haemangioma of the liver which enlarged rapidly while the patient was receiving exogenous oestrogens is reported. A dramatic decrease in the size of the tumour was produced by Iigating the right hepatic artery and portal vein. The literature on large haemangiomas of the liver is reviewed.S. Afr. Med. J., 48, 695 (1974)

Finding Needles in the Right Haystack: Double Modals in Medical Consultations

In this paper we present a case study of a syntactic sociolinguistic variable that has resisted previous attempts at quantitative analysis of usage, the double modal construction of Southern United States English (e.g., You know what might could help that is losing some weight). While naturally-occurring double modals have been exceedingly rare in sociolinguistic interviews, our study represents the very first corpus investigation of double modals through a search of the right ‘haystack’: the nationwide Verilogue, Inc database of recorded and transcribed physician-patient interactions (~85 million words). As a vast source of potentially face-threatening negotiations, the Verilogue corpus provides the ideal speech situation in which to search for low frequency, non-standard syntactic features like the double modal. A quantitative analysis of the 76 tokens extracted from doctor-patient consultations in the US South revealed that double modals are favored by doctors, especially women and those with many decades of professional experience. Among patients, those not currently in employment use double modals more frequently than the employed. We interpreted these findings with reference to the literature on the pragmatics of physician-patient talk, arguing that the double modal is used to negotiate the imbalanced power dynamic of a doctor-patient consultation. In general, the greater use of double modals by doctors shows that the construction is an active part of a doctor’s repertoire for mitigating directives. Collectively, we present a complex socio-pragmatic picture of double modal use that could not be seen without a corpus of naturally-occurring speech in a potentially face-threatening speech situation

Enlargement of Cavernous Haemangioma Associated with Exogenous Administration of Oestrogens

A cavernous haemangioma of the liver which enlarged rapidly while the patient was receiving exogenous oestrogens is reported. A dramatic decrease in the size of the tumour was produced by ligating the right hepatic artery and portal vein. The literature on large haemangiomas of the liver is reviewed.S. Afr. Med. J., 48, 695 (1974)

Coexistence of glassy antiferromagnetism and giant magnetoresistance (GMR) in Fe/Cr multilayer structures

Using temperature-dependent magnetoresistance and magnetization measurements on Fe/Cr multilayers that exhibit pronounced giant magnetoresistance (GMR), we have found evidence for the presence of a glassy antiferromagnetic (GAF) phase. This phase reflects the influence of interlayer exchange coupling (IEC) at low temperature (T < 140K) and is characterized by a field-independent glassy transition temperature, Tg, together with irreversible behavior having logarithmic time dependence below a "de Almeida and Thouless" (AT) critical field line. At room temperature, where the GMR effect is still robust, IEC plays only a minor role, and it is the random potential variations acting on the magnetic domains that are responsible for the antiparallel interlayer domain alignment.Comment: 5 pages, 4 figure

Force-clamp analysis techniques reveal stretched exponential unfolding kinetics in ubiquitin

Force-clamp spectroscopy reveals the unfolding and disulfide bond rupture times of single protein molecules as a function of the stretching force, point mutations and solvent conditions. The statistics of these times reveal whether the protein domains are independent of one another, the mechanical hierarchy in the polyprotein chain, and the functional form of the probability distribution from which they originate. It is therefore important to use robust statistical tests to decipher the correct theoretical model underlying the process. Here we develop multiple techniques to compare the well-established experimental data set on ubiquitin with existing theoretical models as a case study. We show that robustness against filtering, agreement with a maximum likelihood function that takes into account experimental artifacts, the Kuiper statistic test and alignment with synthetic data all identify the Weibull or stretched exponential distribution as the best fitting model. Our results are inconsistent with recently proposed models of Gaussian disorder in the energy landscape or noise in the applied force as explanations for the observed non-exponential kinetics. Since the physical model in the fit affects the characteristic unfolding time, these results have important implications on our understanding of the biological function of proteins

Understanding the decarbonisation of housing: Wales as a case study

International targets requiring UK nations to reduce carbon emissions by at least 80% of 1990 levels by 2050 were made obsolete in 2019. The Climate Change Act now commits UK government to reducing greenhouse gas emissions by at least 100% of 1990 levels by 2050. This includes more stringent emissions targets for the devolved administrations. Welsh Government is responsible for the delivery of decarbonisation in Wales. The Welsh housing stock, among the oldest and least efficient in Europe, produces 21% of national carbon emissions. The CCC report recommends that Wales target no less than a 95% reduction in carbon emissions by 2050. This research explores how policy could deliver this scale of emissions reduction, by predicting the impact of established and emerging 'best practice' retrofit solutions on the existing housing stock. Fourteen recurring dwelling 'types' are identified within the Welsh housing stock (based on physical metrics, condition and tenure) using large data sets. Appropriate retrofit 'narratives' are established and then simulated for each of the fourteen dwelling types. Their impact is measured in terms of capital cost, primary energy use, fuel bills, and carbon emissions. By exploring the impact of a range of approaches to retrofit, and by considering different scenarios for clean energy supply, this research has informed the ongoing development of a route map for delivering decarbonisation targets in Wales