2,322 research outputs found
Mesoscale modeling of the rheology of pressure sensitive adhesives through inclusion of transient forces
For optimal application, pressure-sensitive adhesives must have rheological
properties in between those of a viscoplastic solid and those of a viscoelastic
liquid. Such adhesives can be produced by emulsion polymerisation, resulting in
latex particles which are dispersed in water and contain long-chain acrylic
polymers. When the emulsion is dried, the latex particles coalesce and an
adhesive film is formed. The rheological properties of the dried samples are
believed to be dominated by the interface regions between the original latex
particles, but the relation between rheology and latex particle properties is
poorly understood. In this paper we show that it is possible to describe the
bulk rheology of a pressure-sensitive adhesive by means of a mesoscale
simulation model. To reach experimental time and length scales, each latex
particle is represented by just one simulated particle. The model is subjected
to oscillatory shear flow and extensional flow. Simple order of magnitude
estimates of the model parameters already lead to semi-quantitative agreement
with experimental results. We show that inclusion of transient forces in the
model, i.e. forces with memory of previous configurations, is essential to
correctly predict the linear and nonlinear properties.Comment: 29 pages, 8 figure
A 16-channel Digital TDC Chip with internal buffering and selective readout for the DIRC Cherenkov counter of the BABAR experiment
A 16-channel digital TDC chip has been built for the DIRC Cherenkov counter
of the BaBar experiment at the SLAC B-factory (Stanford, USA). The binning is
0.5 ns, the conversion time 32 ns and the full-scale 32 mus. The data driven
architecture integrates channel buffering and selective readout of data falling
within a programmable time window. The time measuring scale is constantly
locked to the phase of the (external) clock. The linearity is better than 80 ps
rms. The dead time loss is less than 0.1% for incoherent random input at a rate
of 100 khz on each channel. At such a rate the power dissipation is less than
100 mw. The die size is 36 mm2.Comment: Latex, 18 pages, 13 figures (14 .eps files), submitted to NIM
Analyzing powers in inclusive pion production at high energy and the nucleon spin structure
Analyzing powers in inclusive pion production in high energy transversely
polarized proton-proton collisions are studied theoretically in the framework
of the quark recombination model. Calculations by assuming the SU(6)
spin-flavor symmetry for the nucleon structure disagree with the experiments.
We solve this difficulty by taking into account the %We overcome this
difficulty by taking into account the realistic spin distribution functions of
the nucleon, which differs from the SU(6) expectation at large , %but
coincides with a perturbative QCD constraint on the ratio of the unpolarized
valence distributions, as . We also discuss the kaon spin
asymmetry and find in the polarized proton-proton
collisions at large .Comment: 13 pages, 4 figures, late
Numerical Modeling of the Propagation of Infrasonic Acoustic Waves Through the Turbulent Field Generated by the Breaking of Mountain Gravity Waves
The nonlinear propagation of low-frequency acoustic waves through the turbulent fluctuations induced by breaking mountain gravity waves is investigated via 2-D numerical simulations of the Navier-Stokes equations, to understand the effects of atmospheric dynamics on ground-based infrasound measurements. Emphasis is placed on acoustic signals of frequency around 0.1 Hz, traveling through tens-of-kilometers-scale gravity waves and subkilometer-scale turbulence. The sensitivity of the infrasonic phases to small-scale fluctuations is found to depend on the altitudes through which they are refracted toward the Earth. For the considered cases, the dynamics in the stratosphere impact the refracting acoustic waves to a greater extent than those in the thermosphere. This work clearly demonstrates the need for accurate descriptions of the effects of atmospheric dynamics on acoustic propagation, such as here captured by the full set of fluid dynamic equations, as well as of the subsequent effects on measured signals
Clinical update: Heparin-induced thrombocytopenia: An update for the COVID-19 era
The increased use of heparin during the current COVID-19 pandemic has highlighted the risk of a rare but potentially serious complication of heparin therapy, viz. heparin-induced thrombocytopenia (HIT). This is a short review on the pharmacology of heparin and its derivatives, and the pathophysiology of HIT. Guidance on laboratory testing for and clinical management of HIT is presented in accordance with international guidelines. There are important similarities and differences between HIT and the new entity of vaccine-induced immune thrombotic thrombocytopenia, also known as thrombosis with thrombocytopenia syndrome, which clinicians need to be aware of
Analytic curves in algebraic varieties over number fields
We establish algebraicity criteria for formal germs of curves in algebraic
varieties over number fields and apply them to derive a rationality criterion
for formal germs of functions, which extends the classical rationality theorems
of Borel-Dwork and P\'olya-Bertrandias valid over the projective line to
arbitrary algebraic curves over a number field.
The formulation and the proof of these criteria involve some basic notions in
Arakelov geometry, combined with complex and rigid analytic geometry (notably,
potential theory over complex and -adic curves). We also discuss geometric
analogues, pertaining to the algebraic geometry of projective surfaces, of
these arithmetic criteria.Comment: 55 pages. To appear in "Algebra, Arithmetic, and Geometry: In Honor
of Y.i. Manin", Y. Tschinkel & Yu. Manin editors, Birkh\"auser, 200
Ranking ligand affinity for the DNA minor groove by experiment and simulation
The structural and thermodynamic basis for the strength and selectivity of the interactions of minor-groove binders (MGBs) with DNA is not fully understood. In 2003 we reported the first example of a thiazole containing MGB that bound in a phase shifted pattern that spanned 6 base-pairs rather than the usual 4 (for tricyclic distamycin-like compounds). Since then, using DNA footprinting, nuclear magnetic resonance spectroscopy, isothermal titration calorimetry and molecular dynamics, we have established that the flanking bases around the central 4 being read by the ligand have subtle effects on recognition. We have investigated the effect of these flanking sequences on binding and the reasons for the differences and established a computational method to rank ligand affinity against varying DNA sequences
Randomness Increases Order in Biological Evolution
n this text, we revisit part of the analysis of anti-entropy in Bailly and Longo (2009} and develop further theoretical reflections. In particular, we analyze how randomness, an essential component of biological variability, is associated to the growth of biological organization, both in ontogenesis and in evolution. This approach, in particular, focuses on the role of global entropy production and provides a tool for a mathematical understanding of some fundamental observations by Gould on the increasing phenotypic complexity along evolution. Lastly, we analyze the situation in terms of theoretical symmetries, in order to further specify the biological meaning of anti-entropy as well as its strong link with randomness
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