Aircraft control system

An aircraft control system is described which is particularly suited to rotary wing aircraft. Longitudinal acceleration and course rate commands are derived from a manual control stick to control translational velocity of the aircraft along a flight path. In the collective channel the manual controls provide vertical velocity commands. In the yaw channel the manual controls provide sideslip or heading rate commands at high or low airspeeds, respectively. The control system permits pilots to fly along prescribed flight paths in a precise manner with relatively low work load

Fixed-base simulation evaluation of various low-visibility landing systems for helicopters

Fixed base simulation evaluation of one fully automatic and six manual low visibility landing systems for helicopter

TCTP in Development and Cancer

The translationally controlled tumor protein (TCTP) is highly conserved among animal species. It is widely expressed in many different tissues. It is involved in regulating many fundamental processes, such as cell proliferation and growth, apoptosis, pluripotency, and the cell cycle. Hence, it is not surprising that it is essential for normal development and, if misregulated, can lead to cancer. Provided herein is an overview of the diverse functions of TCTP, with a focus on development. Furthermore, we discuss possible ways by which TCTP misregulation or mutation could result in cancer

Quantum phases of hardcore bosons with repulsive dipolar density-density interactions on two-dimensional lattices

We analyse the ground-state quantum phase diagram of hardcore Bosons interacting with repulsive dipolar potentials. The bosons dynamics is described by the extended-Bose-Hubbard Hamiltonian on a two-dimensional lattice. The ground state results from the interplay between the lattice geometry and the long-range interactions, which we account for by means of a classical spin mean-field approach limited by the size of the considered unit cells. This extended classical spin mean-field theory accounts for the long-range density-density interaction without truncation. We consider three different lattice geometries: square, honeycomb, and triangular. In the limit of zero hopping the ground state is always a devil's staircase of solid (gapped) phases. Such crystalline phases with broken translational symmetry are robust with respect to finite hopping amplitudes. At intermediate hopping amplitudes, these gapped phases melt, giving rise to various lattice supersolid phases, which can have exotic features with multiple sublattice densities. At sufficiently large hoppings the ground state is a superfluid. The stability of phases predicted by our approach is gauged by comparison to the known quantum phase diagrams of the Bose-Hubbard model with nearest-neighbour interactions as well as quantum Monte Carlo simulations for the dipolar case on the square lattice. Our results are of immediate relevance for experimental realisations of self-organised crystalline ordering patterns in analogue quantum simulators, e.g., with ultracold dipolar atoms in an optical lattice.Comment: 31 pages, 9 figure

Systematic Analysis of Crystalline Phases in Bosonic Lattice Models with Algebraically Decaying Density-Density Interactions

We propose a general approach to analyse diagonal ordering patterns in bosonic lattice models with algebraically decaying density-density interactions on arbitrary lattices. The key idea is a systematic search for the energetically best order on all unit cells of the lattice up to a given extent. Using resummed couplings we evaluate the energy of the ordering patterns in the thermodynamic limit using finite unit cells. We apply the proposed approach to the atomic limit of the extended Bose-Hubbard model on the triangular lattice at fillings $f=1/2$ and $f=1$. We investigate the ground-state properties of the antiferromagnetic long-range Ising model on the triangular lattice and determine a six-fold degenerate plain-stripe phase to be the ground state for finite decay exponents. We also probe the classical limit of the Fendley-Sengupta-Sachdev model describing Rydberg atom arrays. We focus on arrangements where the atoms are placed on the sites or links of the Kagome lattice. \changed{Our method provides a general framework to treat cristalline structures resulting from long-range interactions.Comment: 35 pages, 11 figure

Characteristics and homogeneity of N6-methylation in human genomes.

A novel DNA modification, N-6 methylated deoxyadenosine (m6dA), has recently been discovered in eukaryotic genomes. Despite its low abundance in eukaryotes, m6dA is implicated in human diseases such as cancer. It is therefore important to precisely identify and characterize m6dA in the human genome. Here, we identify m6dA sites at nucleotide level, in different human cells, genome wide. We compare m6dA features between distinct human cells and identify m6dA characteristics in human genomes. Our data demonstrates for the first time that despite low m6dA abundance, the m6dA mark does often occur consistently at the same genomic location within a given human cell type, demonstrating m6dA homogeneity. We further show, for the first time, higher levels of m6dA homogeneity within one chromosome. Most m6dA are found on a single chromosome from a diploid sample, suggesting inheritance. Our transcriptome analysis not only indicates that human genes with m6dA are associated with higher RNA transcript levels but identifies allele-specific gene transcripts showing haplotype-specific m6dA methylation, which are implicated in different biological functions. Our analyses demonstrate the precision and consistency by which the m6dA mark occurs within the human genome, suggesting that m6dA marks are precisely inherited in humans

What Does an Exemplary Middle School Mathematics Teacher Look Like? The Use of a Professional Development Rubric

A School University Research Network (SURN) committee composed of current mathematics teachers, central office math supervisors, building administrators, mathematicians, and mathematics educators researched numerous sources regarding best practices in mathematics instruction. The resulting professional development rubric synthesizes their findings and can serve a professional development role by providing teachers and administrators with a tool to develop clarity and consensus on best mathematics instructional practices, and how these practices are implemented in the classroom. It is also being used as a tool for cooperating teachers in their supervision of student teachers and as a reflective method for self-evaluation

Creating More Integrated Schools in a Segregated System: A Window of Opportunity

The city of Richmond is changing. Over the past decade, an influx of young, white professionals and families has fueled population growth. And increases in the residential population of white families have very slowly translated into increases in the enrollment of white students in Richmond Public Schools (RPS). These shifts come on the heels of decades of intentional division of and disinvestment in majority black urban communities, offering renewed opportunities for neighborhood and school integration, along with a stronger tax base and increases in school funding. But changing demographics also bring challenges. Both the opportunities and challenges have been on full display during the school rezoning process in RPS. This research brief offers important context and content to inform policy decisions that leverage our city’s growing diversity for increased equity and inclusion. In the sections that follow, we share the robust body of research on the benefits of diverse schools, the current state of integration and relevant historical background influencing the need for action, comparable contemporary experiences, common voluntary integration methods--including best and promising practices and lessons learned--and policy and implementation recommendations informed by this information