Long Range Hydration Effects in Electrolytic Free Suspended Black Films

The force law within free suspended black films made of negatively charged Aerosol-OT (AOT) with added LiCl or CsCl is studied accurately using X-ray reflectivity (ca. 1{\AA}). We find an electrolyte concentration threshold above which a substantial additional repulsion is detected in the LiCl films, up to distances of 100 {\AA}. We interpret this phenomenon as an augmentation of the Debye screening length, due to the local screening of the condensed hydrophilic counterions by the primary hydration shell.Comment: 4 pages, 4 figures, to be published Phys. Rev. Let

MESURE DES GRADIENTS DE DENSITÉ DANS L'INTERACTION LASER-PLASMA

Nous étudions la densité électronique et son gradient dans l'interaction d'un laser à CO2 avec une cible plane de polyéthylène, pour un flux laser de 1012 W/cm2. L'étude par interférométrie Jamin des profils de densité et la mesure strioscopique de son gradient, couplées à l'étude de l'image en rayons X du plasma conduisent à une valeur de 220 ± 80 µm de la longueur du gradient de densité. Ceci est confirmé par des mesures indirectes obtenues à partir du bilan optique de l'interaction et du seuil de génération de l'harmonique 3/2 ω0 du laser à CO2. Les conséquences de ces résultats sur les conditions de l'interaction sont discutées

Observation of the Smectic C -- Smectic I Critical Point

We report the first observation of the smectic C--smectic I (C--I) critical point by Xray diffraction studies on a binary system. This is in confirmity with the theoretical idea of Nelson and Halperin that coupling to the molecular tilt should induce hexatic order even in the C phase and as such both C and I (a tilted hexatic phase) should have the same symmetry. The results provide evidence in support of the recent theory of Defontaines and Prost proposing a new universality class for critical points in layered systems.Comment: 9 pages Latex and 5 postscript figures available from [email protected] on request, Phys.Rev.Lett. (in press

Parametric timed model checking for guaranteeing timed opacity

Information leakage can have dramatic consequences on systems security. Among harmful information leaks, the timing information leakage is the ability for an attacker to deduce internal information depending on the system execution time. We address the following problem: given a timed system, synthesize the execution times for which one cannot deduce whether the system performed some secret behavior. We solve this problem in the setting of timed automata (TAs). We first provide a general solution, and then extend the problem to parametric TAs, by synthesizing internal timings making the TA secure. We study decidability, devise algorithms, and show that our method can also apply to program analysis.Comment: This is the author (and extended) version of the manuscript of the same name published in the proceedings of ATVA 2019. This work is partially supported by the ANR national research program PACS (ANR-14-CE28-0002), the ANR-NRF research program (ProMiS) and by ERATO HASUO Metamathematics for Systems Design Project (No. JPMJER1603), JS

Population pharmacokinetics of colistin and the relation to survival in critically ill patients infected with colistin susceptible and carbapenem-resistant bacteria

Objectives: The aim was to analyse the population pharmacokinetics of colistin and to explore the relationship between colistin exposure and time to death. Methods: Patients included in the AIDA randomized controlled trial were treated with colistin for severe infections caused by carbapenem-resistant Gram-negative bacteria. All subjects received a 9 million units (MU) loading dose, followed by a 4.5 MU twice daily maintenance dose, with dose reduction if creatinine clearance (CrCL) 2 mg/L in 94% (195/208) and 44% (38/87) of patients with CrCL ≤120 mL/min, and >120 mL/min, respectively. Colistin methanesulfonate sodium (CMS) and colistin clearances were strongly dependent on CrCL. High colistin exposure to MIC ratio was associated with increased hazard of death in the multivariate analysis (adjusted hazard ratio (95% CI): 1.07 (1.03–1.12)). Other significant predictors included SOFA score at baseline (HR 1.24 (1.19–1.30) per score increase), age and Acinetobacter or Pseudomonas as index pathogen. Discussion: The population pharmacokinetic model predicted that >90% of the patients had colistin concentrations

Magnetic reconnection driven by electron dynamics

Magnetic reconnections play essential roles in space, astrophysical, and laboratory plasmas, where the anti-parallel magnetic field components re-connect and the magnetic energy is converted to the plasma energy as Alfvénic out flows. Although the electron dynamics is considered to be essential, it is highly challenging to observe electron scale reconnections. Here we show the experimental results on an electron scale reconnection driven by the electron dynamics in laser-produced plasmas. We apply a weak-external magnetic field in the direction perpendicular to the plasma propagation, where the magnetic field is directly coupled with only the electrons but not for the ions. Since the kinetic pressure of plasma is much larger than the magnetic pressure, the magnetic field is distorted and locally anti-parallel. We observe plasma collimations, cusp and plasmoid like features with optical diagnostics. The plasmoid propagates at the electron Alfvén velocity, indicating a reconnection driven by the electron dynamics

X-Ray Reflectivity Study of the Liquid-Expanded Liquid-Condensed Phase Transition

International audienceMonolayers of amphiphilic molecules spread at the air-water interface have been intensively studied using x-ray reflectivity in both the liquid-expanded and the liquid-condensed phase, below and above the triple-point temperature. The phase diagrams of hexadecanoic acid and of the phospholipid L-α DPPC have been investigated. Evidence for the transition is given by an abrupt increase of the aliphatic medium thickness. The results are discussed through recent experimental data and calculations

Phase transitions, elasticity and capillary waves in langmuir monolayers on water: An X-ray optical study

International audienceIn this paper we investigate, by means of X-ray reflectivity at glancing angles, the phase transitions of Langmuir monolayers on water in different compounds (fatty acids and DPPC). We show that the determination of the profile of the electron density normal to the film provide two separate types of information: thicknesses and roughnesses. The thickness of the layer is directly related to the structure of the aliphatic medium and the roughness is due to thermally excited capillary waves. Our study clearly demonstrates that the transition between the so-called liquid-expanded to liquid-condensed phases is characterized by a significant discontinuity of the thickness of the aliphatic medium, whereas at the liquid-condensed to solid transition a strong decrease in the roughness is observed. This striking feature is attributed to the appearance of a rigidity constant of the monolayer in the solid phase