Vibrational dynamics of a two-dimensional microgranular crystal

We study the dynamics of an ordered hexagonal monolayer of polystyrene microspheres adhered to a glass substrate coated with a thin aluminum layer. A laser-induced transient grating technique is employed to generate and detect three types of acoustic modes across the entire Brillouin zone in the Γ−K direction: low-frequency contact-based modes of the granular monolayer, high-frequency modes originating from spheroidal vibrations of the microspheres, and surface Rayleigh waves. The dispersion relation of contact-based and spheroidal modes indicates that they are collective modes of the microgranular crystal controlled by particle-particle contacts. We observe a spheroidal resonance splitting caused by the symmetry breaking due to the substrate, as well as an avoided crossing between the Rayleigh and spheroidal modes. The measurements are found to be in agreement with our analytical model.United States. Department of Energy (Grant DE-FG02-00ER15087)National Science Foundation (U.S.) (Grant CHE-1111557

On the stability of the exact solutions of the dual-phase lagging model of heat conduction

The dual-phase lagging (DPL) model has been considered as one of the most promising theoretical approaches to generalize the classical Fourier law for heat conduction involving short time and space scales. Its applicability, potential, equivalences, and possible drawbacks have been discussed in the current literature. In this study, the implications of solving the exact DPL model of heat conduction in a three-dimensional bounded domain solution are explored. Based on the principle of causality, it is shown that the temperature gradient must be always the cause and the heat flux must be the effect in the process of heat transfer under the dual-phase model. This fact establishes explicitly that the single- and DPL models with different physical origins are mathematically equivalent. In addition, taking into account the properties of the Lambert W function and by requiring that the temperature remains stable, in such a way that it does not go to infinity when the time increases, it is shown that the DPL model in its exact form cannot provide a general description of the heat conduction phenomena

Multiple Sclerosis and Its Relationship with Oxidative Stress, Glutathione Redox System, ATPase System, and Membrane Fluidity

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) with a focus on inflammation, demyelination, and damage to axons leading to neurological deficits. MS pathology is associated with excessive reactive oxygen species (ROS) and generation of reactive nitrogen species (RNS), causing oxidative/nitrosative stress. Deregulation of glutathione homeostasis and alterations in glutathione‐dependent enzymes are implicated in MS. Reactive oxygen species enhance both monocyte adhesion and migration across brain endothelial cells. In addition, ROS can activate the expression of the nuclear transcription factor‐kappa, which upregulates the expression of many genes involved in MS, such as tumor necrosis factor‐α and nitric oxide synthase, among others, leading to mitochondrial dysfunction and energy deficits that result in mitochondrial and cellular calcium overload. Loss of mitochondrial membrane potential can increase the release of cytochrome c, one pathway that leads to neuronal apoptosis. Clinical studies suggest that omega‐3 long‐chain polyunsaturated fatty acids (PUFAs) including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have anti‐inflammatory, antioxidant, and neuroprotective effects in MS and animal models of MS. Here, we review the relationship of oxidative stress, the glutathione redox system, the ATPase system, and membrane fluidity with the development of MS. In addition, we describe the main findings of a clinical trial conducted with relapsing‐remitting MS patients who received a diet supplemented with 4 g/day of fish oil or olive oil. The effects of PUFAs supplementation on the parameters indicated above are analyzed in this work

Efecto del 2,4 Diclorofenoxiacético en la inducción de callos a partir de limbos foliares de Ipomoea batatas (L.) Lam. “camote”

Ipomoea batatas (L.) Lam. “camote”, es un cultivo rústico, de importancia nacional por su valor energético y la presencia de antocianinas ycarotenos. Su manejo agronómico implica su propagación asexual mediante esquejes, siendo la biotecnología vegetal una buena alternativapara la multiplicación masiva, conservación in vitro y/o mejoramiento del cultivo, para ello se hacen uso de reguladores de crecimientovegetal. Uno de ellos es el 2,4 Diclorofenoxiacético (2,4-D), el cual a bajas concentraciones se comporta como una auxina inductora en lageneración de callos. Ante la necesidad de conocimiento en esta área, se propuso como objetivo de investigación determinar el efecto del2,4 Diclorofenoxiacético en la inducción de callos a partir de limbos foliares de I. batatas “camote”. En laboratorio se cultivaron explantes apartir de limbos foliares previamente desinfectados de hojas jóvenes de I. batatas de la variedad amarilla, en medio de cultivo MS,suplementado con ácido 2,4-Diclorofenoxiacético (2,4-D), a las concentraciones de 0 μM; 9,48 μM; 11, 3 μM y 13, 56 μM, empleándose undiseño completamente aleatorizado. A los 50 días de evaluación no se encontró diferencias estadísticamente significativas, sin embargo, enla concentración de 9,48 μM μM de 2,4-D se observó la presencia de un 100 % de callos. Se concluye que el ácido 2,4-Diclorofenoxiacéticoa la concentración de 9,48 μM es favorable en la inducción de callos a partir de limbos foliares de I. batatas (L.) Lam. “camote”. Palabras clave: Embriones somáticos, limbo, camote, 2,4 Diclorofenoxiacético. Abstract Ipomoea batatas (L.) Lam. “camote”, is a rustic crop, of national importance for its energy value and the presence of anthocyanins andcarotenes. Its agronomic management implies its asexual propagation through cuttings, being plant biotechnology a good alternative formassive multiplication, in vitro conservation and/or crop improvement, for this, plant growth regulators are used. One of them is 2.4-Dichlorophenoxyacetic (2.4-D), which at low concentrations behaves as an inducer auxin in the generation of calluses. Given the need forknowledge in this area, it was proposed as a research objective to determine the effect of 2.4-Dichlorophenoxyacetic acid on the inductionof calluses from leaf blades of I. batatas. In the laboratory, explants were grown from previously disinfected leaf blades of young leaves of I.batatas of the yellow variety, in the MS culture medium, supplemented with 2.4-Dichlorophenoxyacetic acid (2.4-D), at the concentrationsof 0 μM; 9.48 μM; 11.3 μM y 13.56 μM, using a completely randomized design. At 50 days of evaluation, no statistically significant differenceswere found, however, at the 9.48 μM concentration of 2.4-D the presence of 100% calluses was observed. It is concluded that 2.4-Dichlorophenoxyacetic acid at a concentration of 9.48 μM is favorable in the induction of calluses from leaf blades of I. batatas (L.) Lam."sweet potato". Keywords: Somatic embryos, limbus, sweet potato, 2,4 Dichlorophenoxyacetic. *Autor para correspondencia: [email protected] DOI: http://dx.doi.org/10.17268/rebiol.2021.41.01.1

Small molecule sensitization to TRAIL is mediated via nuclear localization, phosphorylation and inhibition of chaperone activity of Hsp27

10.1038/cddis.2013.413Cell Death and Disease410

Fungal planet description sheets: 951–1041

Novel species of fungi described in this study include those from various countries as follows: Antarctica , Apenidiella antarctica from permafrost, Cladosporium fildesense fromanunidentifiedmarinesponge. Argentina , Geastrum wrightii onhumusinmixedforest. Australia , Golovinomyces glandulariae on Glandularia aristigera, Neoanungitea eucalyptorum on leaves of Eucalyptus grandis, Teratosphaeria corymbiicola on leaves of Corymbia ficifolia, Xylaria eucalypti on leaves of Eucalyptus radiata. Brazil, Bovista psammophila on soil, Fusarium awaxy on rotten stalks of Zea mays, Geastrum lanuginosum on leaf litter covered soil, Hermetothecium mikaniae-micranthae (incl. Hermetothecium gen. nov.)on Mikania micrantha, Penicillium reconvexovelosoi in soil, Stagonosporopsis vannaccii from pod of Glycine max. British Virgin Isles , Lactifluus guanensis onsoil. Canada , Sorocybe oblongispora on resin of Picea rubens. Chile, Colletotrichum roseum on leaves of Lapageria rosea. China, Setophoma caverna fromcarbonatiteinKarstcave. Colombia , Lareunionomyces eucalypticola on leaves of Eucalyptus grandis. Costa Rica, Psathyrella pivae onwood. Cyprus , Clavulina iris oncalcareoussubstrate. France , Chromosera ambigua and Clavulina iris var. occidentalis onsoil. French West Indies , Helminthosphaeria hispidissima ondeadwood. Guatemala , Talaromyces guatemalensis insoil. Malaysia , Neotracylla pini (incl. Tracyllales ord. nov. and Neotra- cylla gen. nov.)and Vermiculariopsiella pini on needles of Pinus tecunumanii. New Zealand, Neoconiothyrium viticola on stems of Vitis vinifera, Parafenestella pittospori on Pittosporum tenuifolium, Pilidium novae-zelandiae on Phoenix sp. Pakistan , Russula quercus-floribundae onforestfloor. Portugal , Trichoderma aestuarinum from salinewater. Russia , Pluteus liliputianus on fallen branch of deciduous tree, Pluteus spurius on decaying deciduouswoodorsoil. South Africa , Alloconiothyrium encephalarti, Phyllosticta encephalarticola and Neothyrostroma encephalarti (incl. Neothyrostroma gen. nov.)onleavesof Encephalartos sp., Chalara eucalypticola on leaf spots of Eucalyptus grandis × urophylla, Clypeosphaeria oleae on leaves of Olea capensis, Cylindrocladiella postalofficium on leaf litter of Sideroxylon inerme , Cylindromonium eugeniicola (incl. Cylindromonium gen. nov.)onleaflitterof Eugenia capensis , Cyphellophora goniomatis on leaves of Gonioma kamassi , Nothodactylaria nephrolepidis (incl. Nothodactylaria gen. nov. and Nothodactylariaceae fam. nov.)onleavesof Nephrolepis exaltata , Falcocladium eucalypti and Gyrothrix eucalypti on leaves of Eucalyptus sp., Gyrothrix oleae on leaves of Olea capensis subsp. macrocarpa , Harzia metro sideri on leaf litter of Metrosideros sp., Hippopotamyces phragmitis (incl. Hippopota- myces gen. nov.)onleavesof Phragmites australis , Lectera philenopterae on Philenoptera violacea , Leptosillia mayteni on leaves of Maytenus heterophylla , Lithohypha aloicola and Neoplatysporoides aloes on leaves of Aloe sp., Millesimomyces rhoicissi (incl. Millesimomyces gen. nov.) on leaves of Rhoicissus digitata , Neodevriesia strelitziicola on leaf litter of Strelitzia nicolai , Neokirramyces syzygii (incl. Neokirramyces gen. nov.)onleafspots o

Fingerprints as Predictors of Schizophrenia: A Deep Learning Study

Background and hypothesis: The existing developmental bond between fingerprint generation and growth of the central nervous system points to a potential use of fingerprints as risk markers in schizophrenia. However, the high complexity of fingerprints geometrical patterns may require flexible algorithms capable of characterizing such complexity. Study design: Based on an initial sample of scanned fingerprints from 612 patients with a diagnosis of non-affective psychosis and 844 healthy subjects, we have built deep learning classification algorithms based on convolutional neural networks. Previously, the general architecture of the network was chosen from exploratory fittings carried out with an independent fingerprint dataset from the National Institute of Standards and Technology. The network architecture was then applied for building classification algorithms (patients vs controls) based on single fingers and multi-input models. Unbiased estimates of classification accuracy were obtained by applying a 5-fold cross-validation scheme. Study results: The highest level of accuracy from networks based on single fingers was achieved by the right thumb network (weighted validation accuracy = 68%), while the highest accuracy from the multi-input models was attained by the model that simultaneously used images from the left thumb, index and middle fingers (weighted validation accuracy = 70%). Conclusion: Although fitted models were based on data from patients with a well established diagnosis, since fingerprints remain lifelong stable after birth, our results imply that fingerprints may be applied as early predictors of psychosis. Specially, if they are used in high prevalence subpopulations such as those of individuals at high risk for psychosis.This work was supported by several grants funded by the Instituto de Salud Carlos III and the Spanish Ministry of Science and Innovation (co-funded by the European Regional Development Fund/European Social Fund “Investing in your future”): Miguel Servet Research Contract (CPII13/00018 to RS, CPII16/00018 to EP-C, CP20/00072 to MF-V), PFIS Contract (FI19/0352 to MG-R). Research Mobility programme (MV18/00054 to EP-C), Research Projects (PI18/00877 and PI21/00525 to RS). It has also been supported by the Centro de Investigación Biomédica en Red de Salud Mental and the Generalitat de Catalunya: 2014SGR1573 and 2017SGR1365 to EP-C and SLT008/18/00206 to IF-R from the Departament de Salut. The authors have declared that there are no conflicts of interest in relation to the subject of this study.S

Global transpiration data from sap flow measurements: the SAPFLUXNET database

Plant transpiration links physiological responses of vegetation to water supply and demand with hydrological, energy, and carbon budgets at the land?atmosphere interface. However, despite being the main land evaporative flux at the global scale, transpiration and its response to environmental drivers are currently not well constrained by observations. Here we introduce the first global compilation of whole-plant transpiration data from sap flow measurements (SAPFLUXNET, https://sapfluxnet.creaf.cat/, last access: 8 June 2021). We harmonized and quality-controlled individual datasets supplied by contributors worldwide in a semi-automatic data workflow implemented in the R programming language. Datasets include sub-daily time series of sap flow and hydrometeorological drivers for one or more growing seasons, as well as metadata on the stand characteristics, plant attributes, and technical details of the measurements. SAPFLUXNET contains 202 globally distributed datasets with sap flow time series for 2714 plants, mostly trees, of 174 species. SAPFLUXNET has a broad bioclimatic coverage, with woodland/shrubland and temperate forest biomes especially well represented (80 % of the datasets). The measurements cover a wide variety of stand structural characteristics and plant sizes. The datasets encompass the period between 1995 and 2018, with 50 % of the datasets being at least 3 years long. Accompanying radiation and vapour pressure deficit data are available for most of the datasets,while on-site soil water content is available for 56 % of the datasets. Many datasets contain data for species that make up 90 % or more of the total stand basal area, allowing the estimation of stand transpiration in diverse ecological settings. SAPFLUXNET adds to existing plant trait datasets, ecosystem flux networks, and remote sensing products to help increase our understanding of plant water use, plant responses to drought, and ecohydrological processes.Fil: Poyatos, Rafael. Universitat Autònoma de Barcelona; EspañaFil: Granda, Víctor. Universitat Autònoma de Barcelona; EspañaFil: Flo, Víctor. Universitat Autònoma de Barcelona; EspañaFil: Adams, Mark A.. Swinburne University of Technology; Australia. University of Sydney; AustraliaFil: Adorján, Balázs. University of Debrecen; HungríaFil: Aguadé, David. Universitat Autònoma de Barcelona; EspañaFil: Aidar, Marcos P. M.. Institute of Botany; BrasilFil: Allen, Scott. University of Nevada; Estados UnidosFil: Alvarado Barrientos, M. Susana. Instituto de Ecología A.C.; MéxicoFil: Anderson Teixeira, Kristina J.. Smithsonian Tropical Research Institute; PanamáFil: Aparecido, Luiza Maria. Arizona State University; Estados Unidos. Texas A&M University; Estados UnidosFil: Arain, M. Altaf. McMaster University; CanadáFil: Aranda, Ismael. National Institute for Agricultural and Food Research and Technology; EspañaFil: Asbjornsen, Heidi. University of New Hampshire; Estados UnidosFil: Robert Baxter. Durham University; Reino UnidoFil: Beamesderfer, Eric. McMaster University; Canadá. Northern Arizona University; Estados UnidosFil: Carter Berry, Z.. Chapman University; Estados UnidosFil: Berveiller, Daniel. Université Paris Saclay; Francia. Centre National de la Recherche Scientifique; FranciaFil: Blakely, Bethany. University of Illinois at Urbana-Champaign; Estados UnidosFil: Boggs, Johnny. United States Forest Service; Estados UnidosFil: Gil Bohrer. Ohio State University; Estados UnidosFil: Bolstad, Paul V.. University of Minnesota; Estados UnidosFil: Bonal, Damien. Université de Lorraine; FranciaFil: Bracho, Rosvel. University of Florida; Estados UnidosFil: Brito, Patricia. Universidad de La Laguna; EspañaFil: Brodeur, Jason. McMaster University; CanadáFil: Casanoves, Fernando. Centro Agronómico Tropical de Investigación y Enseñanza; Costa RicaFil: Chave, Jérôme. Université Paul Sabatier; FranciaFil: Chen, Hui. Xiamen University; ChinaFil: Peri, Pablo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Santa Cruz. Universidad Tecnológica Nacional. Facultad Regional Santa Cruz. Centro de Investigaciones y Transferencia de Santa Cruz. Universidad Nacional de la Patagonia Austral. Centro de Investigaciones y Transferencia de Santa Cruz; Argentin