1,160 research outputs found
Effects of heavy modes on vacuum stability in supersymmetric theories
We study the effects induced by heavy fields on the masses of light fields in
supersymmetric theories, under the assumption that the heavy mass scale is much
higher than the supersymmetry breaking scale. We show that the square-masses of
light scalar fields can get two different types of significant corrections when
a heavy multiplet is integrated out. The first is an indirect level-repulsion
effect, which may arise from heavy chiral multiplets and is always negative.
The second is a direct coupling contribution, which may arise from heavy vector
multiplets and can have any sign. We then apply these results to the sGoldstino
mass and study the implications for the vacuum metastability condition. We find
that the correction from heavy chiral multiplets is always negative and tends
to compromise vacuum metastability, whereas the contribution from heavy vector
multiplets is always positive and tends on the contrary to reinforce it. These
two effects are controlled respectively by Yukawa couplings and gauge charges,
which mix one heavy and two light fields respectively in the superpotential and
the Kahler potential. Finally we also comment on similar effects induced in
soft scalar masses when the heavy multiplets couple both to the visible and the
hidden sector.Comment: LaTex, 24 pages, no figures; v2 some comments and references adde
Diaphragmatic paralysis, respiratory function, and postoperative pain after interscalene brachial plexus block with a reduced dose of 10 ml levobupivacaine 0.25% versus a 20 ml dose in patients undergoing arthroscopic shoulder surgery: study protocol for the randomized controlled double-blind Redole
Background: Arthroscopic shoulder surgery causes severe postoperative pain. An interscalene brachial plexus block provides adequate analgesia, but unintended spread of the local anesthetic administered may result in a phrenic nerve block, usually associated with a nonnegligible incidence of acute hemidiaphragmatic paralysis. The main purpose of this trial will be to analyze the incidence of hemidiaphragmatic paralysis ensuing after interscalene brachial plexus block in patients undergoing arthroscopic shoulder surgery administered a standard volume (20 ml) vs. a low volume (10 ml) of levobupivacaine 0.25%. Methods: This will be a prospective double-blind randomized controlled single-center two-arm comparative trial. Forty-eight patients will be included. The primary goal will be to ultrasonographically determine the incidence of hemidiaphragmatic paralysis by calculating the diaphragmatic thickness ratio in each group. The secondary goals will be to compare the two arms in terms of (1) decrease in forced vital capacity and (2) in forced expiratory volume at 1 s by spirometry; (3) decrease in diaphragmatic excursion by ultrasound; (4) 24-h total intravenous morphine consumption; (5) time to first opioid request of a patient-controlled analgesia pump; and (6) postoperative complications. Discussion: This trial will demonstrate that a low-volume interscalene brachial plexus block decreases hemidiaphragmatic paralysis following arthroscopic shoulder surgery according to spirometry and ultrasound measurements and does not provide inferior postoperative analgesia to the standard volume, as measured by opioid requirements. Trial registration: EudraCT and Spanish Trial Register (REec) registration number: 2019-003855-12 (registered on 7 January 2020). ClinicalTrials.gov identification number: NCT04385966 (retrospectively registered on 8 May 2020). Ethics Committee approval: EC19/093 (18 December 2019)
Simultaneous circulation of genotypes I and III of dengue virus 3 in Colombia
<p>Abstract</p> <p>Background</p> <p>Dengue is a major health problem in tropical and subtropical regions. In Colombia, dengue viruses (DENV) cause about 50,000 cases annually, 10% of which involve Dengue Haemorrhagic Fever/Dengue Shock Syndrome. The picture is similar in other surrounding countries in the Americas, with recent outbreaks of severe disease, mostly associated with DENV serotype 3, strains of the Indian genotype, introduced into the Americas in 1994.</p> <p>Results</p> <p>The analysis of the 3'end (224 bp) of the envelope gene from 32 DENV-3 strains recently recovered in Colombia confirms the circulation of the Indian genotype, and surprisingly the co-circulation of an Asian-Pacific genotype only recently described in the Americas.</p> <p>Conclusion</p> <p>These results have important implications for epidemiology and surveillance of DENV infection in Central and South America. Molecular surveillance of the DENV genotypes infecting humans could be a very valuable tool for controlling/mitigating the impact of the DENV infection.</p
Inflation with racetrack superpotential and matter field
Several models of inflation with the racetrack superpotential for the volume
modulus coupled to a matter field are investigated. In particular, it is shown
that two classes of racetrack inflation models, saddle point and inflection
point ones, can be constructed in a fully supersymmetric framework with the
matter field F-term as a source of supersymmetry breaking and uplifting. Two
models of F-term supersymmetry breaking are considered: the Polonyi model and
the quantum corrected O'Raifeartaigh model. In the former case, both classes of
racetrack inflation models differ significantly from the corresponding models
with non-supersymmetric uplifting. The main difference is a quite strong
dominance of the inflaton by the matter field. In addition, fine-tuning of the
parameters is relaxed as compared to the original racetrack models. In the case
of the racetrack inflation models coupled to the O'Raifeartaigh model, the
matter field is approximately decoupled from the inflationary dynamics. In all
of the above models the gravitino mass is larger than the Hubble scale during
inflation. The possibility of having the gravitino much lighter than the Hubble
scale is also investigated. It is very hard to construct models with light
gravitino in which the volume modulus dominates inflation. On the other hand,
models in which the inflationary dynamics is dominated by the matter field are
relatively simple and seem to be more natural.Comment: 40 pages, 13 figures, references added, typos corrected, version to
be publishe
Gauge vs. Gravity mediation in models with anomalous U(1)'s
In an attempt to implement gauge mediation in string theory, we study string
effective supergravity models of supersymmetry breaking, containing anomalous
gauge factors. We discuss subtleties related to gauge invariance and the
stabilization of the Green-Schwarz moduli, which set non-trivial constraints on
the transmission of supersymmetry breaking to MSSM via gauge interactions.
Given those constraints, it is difficult to obtain the dominance of gauge
mediation over gravity mediation. Furthermore, generically the gauge
contributions to soft terms contain additional non-standard terms coming from
D-term contributions. Motivated by this, we study the phenomenology of recently
proposed hybrid models, where gravity and gauge mediations compete at the GUT
scale, and show that such a scenario can respect WMAP constraints and would be
easily testable at LHC.Comment: 40 pages, 5 figure
- …