Genetic Family and Stock Type Influence Simulated Loblolly Pine Yields from Wet Sites

Planting adapted families or a bulked seedlot of bare-root and container-grown-seedlings of loblolly pine (Pinus taeda L) were contrasted as cost effective alternatives for regenerating Arkansas\u27 wet sites. Survival data from two wet sites were used to simulate 15 years of growth. Containerized seedlings provided 17% greater survival than bare-root seedlings, but yielded a lower present net worth than bare-root seedlings. Planting families adapted to excessive moisture provided 7% greater survival and yielded a greater present net worth than planting a bulked seedlot consisting of adapted and poorly adapted families

Study of perturbed periodic systems of differential equations - The Stroboscopic method

Stroboscopic method for solving perturbed periodic systems of differential equation

A Comparison of Appalachian and Non-Appalachian Kentucky DUI Offenders

Background: Driving under the influence has been an overlooked consequence of the opioid epidemic. Although recent reports have highlighted the increased prevalence of DUI in rural communities and the extensive mental health problems and criminal and drug use histories among rural Appalachian DUI offenders, it is unclear how Appalachian DUI populations compare to DUI offenders in other regions. Purpose: To help fill this void in the literature, the current study uses a statewide sample to examine how Appalachian DUI offenders differ from non-Appalachian DUI offenders in a predominantly rural state. Methods: Assessment records were examined for 11,640 Kentucky DUI offenders who completed an intervention in 2017. Appalachian DUI offenders were compared to non-Appalachian metro and nonmetro DUI offenders. Demographic information, DUI violation details, DSM-5 substance-use disorder criteria, and referral information were compared using ANCOVAs and logistic regression models. Results: More than one fourth of the sample were convicted in an Appalachian county. Compared to non-Appalachian DUI offenders, Appalachian offenders were significantly older and more likely to have a prior DUI conviction, to meet DSM-5 criteria for a drug-use disorder, and to drive while drug-impaired. Referral and intervention compliance also varied across groups. Implications: Results suggest that Appalachian DUI offenders are more drug-involved and have increased risk of recidivism. Findings indicate a need for practitioners to consider the distinct needs of Appalachian DUI offenders during service delivery. Future research should explore alternative intervention methods for preventing continued impaired driving in Appalachia given limited treatment availability in the region

On Nichols algebras over PGL(2,q) and PSL(2,q)

We compute necessary conditions on Yetter-Drinfeld modules over the groups \mathbf{PGL}(2,q)=\mathbf{PGL}(2,\FF_q) and \mathbf{PSL}(2,q)=\mathbf{PSL}(2,\FF_q) to generate finite dimensional Nichols algebras. This is a first step towards a classification of pointed Hopf algebras with group of group-likes isomorphic to one of these groups. As a by-product of the techniques developed in this work, we prove that there is no non-trivial finite-dimensional pointed Hopf algebra over the Mathieu groups $M_{20}$ and $M_{21}=\mathbf{PSL}(3,4)$.Comment: Minor change

β-adrenergic-mediated dynamic augmentation of sarcolemmal CaV 1.2 clustering and co-operativity in ventricular myocytes.

Key pointsPrevailing dogma holds that activation of the β-adrenergic receptor/cAMP/protein kinase A signalling pathway leads to enhanced L-type CaV 1.2 channel activity, resulting in increased Ca2+ influx into ventricular myocytes and a positive inotropic response. However, the full mechanistic and molecular details underlying this phenomenon are incompletely understood. CaV 1.2 channel clusters decorate T-tubule sarcolemmas of ventricular myocytes. Within clusters, nanometer proximity between channels permits Ca2+ -dependent co-operative gating behaviour mediated by physical interactions between adjacent channel C-terminal tails. We report that stimulation of cardiomyocytes with isoproterenol, evokes dynamic, protein kinase A-dependent augmentation of CaV 1.2 channel abundance along cardiomyocyte T-tubules, resulting in the appearance of channel 'super-clusters', and enhanced channel co-operativity that amplifies Ca2+ influx. On the basis of these data, we suggest a new model in which a sub-sarcolemmal pool of pre-synthesized CaV 1.2 channels resides in cardiomyocytes and can be mobilized to the membrane in times of high haemodynamic or metabolic demand, to tune excitation-contraction coupling.AbstractVoltage-dependent L-type CaV 1.2 channels play an indispensable role in cardiac excitation-contraction coupling. Activation of the β-adrenergic receptor (βAR)/cAMP/protein kinase A (PKA) signalling pathway leads to enhanced CaV 1.2 activity, resulting in increased Ca2+ influx into ventricular myocytes and a positive inotropic response. CaV 1.2 channels exhibit a clustered distribution along the T-tubule sarcolemma of ventricular myocytes where nanometer proximity between channels permits Ca2+ -dependent co-operative gating behaviour mediated by dynamic, physical, allosteric interactions between adjacent channel C-terminal tails. This amplifies Ca2+ influx and augments myocyte Ca2+ transient and contraction amplitudes. We investigated whether βAR signalling could alter CaV 1.2 channel clustering to facilitate co-operative channel interactions and elevate Ca2+ influx in ventricular myocytes. Bimolecular fluorescence complementation experiments reveal that the βAR agonist, isoproterenol (ISO), promotes enhanced CaV 1.2-CaV 1.2 physical interactions. Super-resolution nanoscopy and dynamic channel tracking indicate that these interactions are expedited by enhanced spatial proximity between channels, resulting in the appearance of CaV 1.2 'super-clusters' along the z-lines of ISO-stimulated cardiomyocytes. The mechanism that leads to super-cluster formation involves rapid, dynamic augmentation of sarcolemmal CaV 1.2 channel abundance after ISO application. Optical and electrophysiological single channel recordings confirm that these newly inserted channels are functional and contribute to overt co-operative gating behaviour of CaV 1.2 channels in ISO stimulated myocytes. The results of the present study reveal a new facet of βAR-mediated regulation of CaV 1.2 channels in the heart and support the novel concept that a pre-synthesized pool of sub-sarcolemmal CaV 1.2 channel-containing vesicles/endosomes resides in cardiomyocytes and can be mobilized to the sarcolemma to tune excitation-contraction coupling to meet metabolic and/or haemodynamic demands

Dynamical Tide in Solar-Type Binaries

Circularization of late-type main-sequence binaries is usually attributed to turbulent convection, while that of early-type binaries is explained by resonant excitation of g modes. We show that the latter mechanism operates in solar-type stars also and is at least as effective as convection, despite inefficient damping of g modes in the radiative core. The maximum period at which this mechanism can circularize a binary composed of solar-type stars in 10 Gyr is as low as 3 days, if the modes are damped by radiative diffusion only and g-mode resonances are fixed; or as high as 6 days, if one allows for evolution of the resonances and for nonlinear damping near inner turning points. Even the larger theoretical period falls short of the observed transition period by a factor two.Comment: 17 pages, 2 postscript figures, uses aaspp4.sty. Submitted to Ap