1,261 research outputs found
Detection of Optical Synchrotron Emission from the Radio Jet of 3C279
We report the detection of optical and ultraviolet emission from the
kiloparsec scale jet of the well-known quasar 3C~279. A bright knot, discovered
in archival V and U band {\it Hubble Space Telescope} Faint Object Camera
images, is coincident with a peak in the radio jet \sim0.6\arcsec from the
nucleus. The detection was also confirmed in Wide Field Planetary Camera-2
images. Archival Very Large Array and MERLIN radio data are also analyzed which
help to show that the high-energy optical/UV continuum, and spectrum, are
consistent with a synchrotron origin from the same population of relativistic
electrons responsible for the radio emission.Comment: 6 pages, 3 figs. accepted for publication in ApJL with minor
revision
De Hoge Born verbindt: kwaliteiten en effecten van zorgboerderij De Hoge Born
De Hoge Born blijkt voor zorgvragers een plek te zijn 'waar je mag zijn wie je bent', waar 'je jezelf met je problemen leert accepteren' en 'zelfvertrouwen en eigenwaarde ontwikkelt'. Dit legt een basis voor hun verdere ontwikkeling. Bij de meeste zorgvragers die langere tijd zijn gevolgd met het monitoringsinstrument werden betrouwbare positieve veranderingen vastgestel
Citrus/Cydonia Comp. Can Restore the Immunological Balance in Seasonal Allergic Rhinitis-Related Immunological Parameters In Vitro
In two in vitro studies, we examined the immunological (pathways of the) effects of Citrus/Cydonia comp. from, respectively, a healthy and an allergic donor; peripheral blood mononuclear cells (PBMCs) were isolated out of peripheral blood and analyzed in vitro after polyclonal stimulation of T-cells. The differentiation capacity and the influence with regard to Th1 (IFN-Îł) and Th2 (IL-5) cells were examined. Citrus/Cydonia comp. has a selective effect on the differentiation of T-cells by producing relatively more IL-10 than IL-12. By that, it also seems to have an effect on the induction of regulatory (IL-10 producing) T-cell subsets. It is in vitro capable of neutralizing (to some extent) the changes, characteristic to allergic rhinitis, with regard to the maturation, differentiation, and activity of the immune system. Thus, Citrus/Cydonia comp. can potentially restore the disturbed immune state of rhinitis patients, which essentially could be sufficient to make allergic symptoms disappear permanently
Radio Emission from the Intermediate-mass Black Hole in the Globular Cluster G1
We have used the Very Large Array (VLA) to search for radio emission from the
globular cluster G1 (Mayall-II) in M31. G1 has been reported by Gebhardt et al.
to contain an intermediate-mass black hole (IMBH) with a mass of ~2 x 10^4
solar masses. Radio emission was detected within an arcsecond of the cluster
center with an 8.4 GHz power of 2 x 10^{15} W/Hz. The radio/X-ray ratio of G1
is a few hundred times higher than that expected for a high-mass X-ray binary
in the cluster center, but is consistent with the expected value for accretion
onto an IMBH with the reported mass. A pulsar wind nebula is also a possible
candidate for the radio and X-ray emission from G1; future high-sensitivity
VLBI observations might distinguish between this possibility and an IMBH. If
the radio source is an IMBH, and similar accretion and outflow processes occur
for hypothesized ~ 1000-solar-mass black holes in Milky Way globular clusters,
they are within reach of the current VLA and should be detectable easily by the
Expanded VLA when it comes on line in 2010.Comment: ApJ Letters, accepted, 11 pages, 1 figur
The Evolution of Cas A at Low Radio Frequencies
We have used archival 74 MHz VLA data spanning the last 15 years in
combination with new data from the Long Wavelength Demonstrator Array (LWDA)
and data from the literature covering the last 50 years to explore the
evolution of Cas A at low radio frequencies. We find that the secular decrease
of the flux density of Cas A at ~80 MHz is rather stable over five decades of
time, decreasing at a rate of 0.7-0.8% yr^-1. This is entirely consistent with
previous estimates at frequencies as low as 38 MHz, indicating that the secular
decrease is roughly the same at low frequencies, at least between 38 and 80
MHz. We also find strong evidence for as many as four modes of flux density
oscillation about the slower secular decrease with periods of 3.10+/-0.02$ yr,
5.1+/-0.3 yr, 9.0+/-0.2 yr, and 24+/-2 yr. These are also consistent with
fluctuations seen previously to occur on scales of a few years. These results
provide compelling motivation for a thorough low frequency monitoring campaign
of Cas A to constrain the nature and physical origins of these fluctuations,
and to be able to better predict the flux density of Cas A at any given epoch
so that it may be used as a reliable low frequency calibrator.Comment: accepted for publication in A
L1CAM binds ErbB receptors through Ig-like domains coupling cell adhesion and neuregulin signalling.
During nervous system development different cell-to-cell communication mechanisms operate in parallel guiding migrating neurons and growing axons to generate complex arrays of neural circuits. How such a system works in coordination is not well understood. Cross-regulatory interactions between different signalling pathways and redundancy between them can increase precision and fidelity of guidance systems. Immunoglobulin superfamily proteins of the NCAM and L1 families couple specific substrate recognition and cell adhesion with the activation of receptor tyrosine kinases. Thus it has been shown that L1CAM-mediated cell adhesion promotes the activation of the EGFR (erbB1) from Drosophila to humans. Here we explore the specificity of the molecular interaction between L1CAM and the erbB receptor family. We show that L1CAM binds physically erbB receptors in both heterologous systems and the mammalian developing brain. Different Ig-like domains located in the extracellular part of L1CAM can support this interaction. Interestingly, binding of L1CAM to erbB enhances its response to neuregulins. During development this may synergize with the activation of erbB receptors through L1CAM homophilic interactions, conferring diffusible neuregulins specificity for cells or axons that interact with the substrate through L1CAM
Time-Frequency Analysis of Rocket Nozzle Wall Pressures During Start-up Transients
Surveys of the fluctuating wall pressure were conducted on a sub-scale, thrust- optimized parabolic nozzle in order to develop a physical intuition for its Fourier-azimuthal mode behavior during fixed and transient start-up conditions. These unsteady signatures are driven by shock wave turbulent boundary layer interactions which depend on the nozzle pressure ratio and nozzle geometry. The focus however, is on the degree of similarity between the spectral footprints of these modes obtained from transient start-ups as opposed to a sequence of fixed nozzle pressure ratio conditions. For the latter, statistically converged spectra are computed using conventional Fourier analyses techniques, whereas the former are investigated by way of time-frequency analysis. The findings suggest that at low nozzle pressure ratios -- where the flow resides in a Free Shock Separation state -- strong spectral similarities occur between fixed and transient conditions. Conversely, at higher nozzle pressure ratios -- where the flow resides in Restricted Shock Separation -- stark differences are observed between the fixed and transient conditions and depends greatly on the ramping rate of the transient period. And so, it appears that an understanding of the dynamics during transient start-up conditions cannot be furnished by a way of fixed flow analysis
A Compact Extreme Scattering Event Cloud Towards AO 0235+164
We present observations of a rare, rapid, high amplitude Extreme Scattering
Event toward the compact BL-Lac AO 0235+164 at 6.65 GHz. The ESE cloud is
compact; we estimate its diameter between 0.09 and 0.9 AU, and is at a distance
of less than 3.6 kpc. Limits on the angular extent of the ESE cloud imply a
minimum cloud electron density of ~ 4 x 10^3 cm^-3. Based on the amplitude and
timescale of the ESE observed here, we suggest that at least one of the
transients reported by Bower et al. (2007) may be attributed to ESEs.Comment: 11 pages, 2 figure
A Search for Active Galactic Nuclei in Sc Galaxies with H II Spectra
(Abridged) We have searched for nuclear radio emission from a statistically
complete sample of 40 Sc galaxies within 30 Mpc that are optically classified
as star-forming objects, in order to determine whether weak AGNs might be
present. Only three nuclear radio sources were detected, in NGC 864, NGC 4123,
and NGC 4535. These galaxies have peak 6-cm radio powers of 10^{20} W/Hz at
arcsecond resolution, while upper limits of the non-detected galaxies typically
range from 10^{18.4} to 10^{20} W/Hz. The three nuclear radio sources all are
resolved and appear to have diffuse morphologies, with linear sizes of ~300 pc.
This strongly indicates that circumnuclear star formation has been detected in
these three H II galaxies. Comparison with previous 20-cm VLA results for the
detected galaxies shows that the extended nuclear radio emission has a flat
spectrum in two objects, and almost certainly is generated by thermal emission
from gas ionized by young stars in the centers of those galaxies. The 6-cm
radio powers are comparable to predictions for thermal emission that are based
on the nuclear H-alpha luminosities, and imply nuclear star formation rates of
0.08-0.8 solar masses/yr, while the low-resolution NRAO VLA Sky Survey implies
galaxy-wide star formation rates of 0.3-1.0 solar masses/yr in stars above 5
solar masses. Although the presence of active nuclei powered by massive black
holes cannot be definitively ruled out, the present results suggest that they
are likely to be rare in these late-type galaxies with H II spectra.Comment: To appear in ApJ. 7 page
Cicrumnuclear Supernova Remnants and HII Regions in NGC 253
Archival VLA data has been used to produce arcsecond-resolution 6- and 20-cm
images of the region surrounding the nuclear 200-pc (~15") starburst in NGC
253. Twenty-two discrete sources stronger than 0.4 mJy have been detected
within ~2 kpc (~3') of the galaxy nucleus; almost all these sources must be
associated with the galaxy. None of the radio sources coincides with a detected
X-ray binary, so they appear to be due to supernova remnants and H II regions.
The region outside the central starburst has a derived radio supernova rate of
<~0.1/yr, and may account for at least 20% of the recent star formation in NGC
253. Most of the newly identified sources have steep, nonthermal radio spectra,
but several relatively strong thermal sources also exist, containing the
equivalent of tens of O5 stars. These stars are spread over tens of parsecs,
and are embedded in regions having average ionized gas densities of
20-200/cm^3, much lower than in the most active nuclear star-forming regions in
NGC 253 or in the super star clusters seen in other galaxies. The strongest
region of thermal emission coincides with a highly reddened area seen at
near-infrared wavelengths, possibly containing optically obscured H II regions.Comment: 17 pages, 3 postscript figures, AASTeX format, in press for
Astronomical Journal, July 200
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