37 research outputs found

    Separation of multiple time delays using new spectral estimation schemes

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    Includes bibliographical references.The problem of estimating multiple time delays in presence of colored noise is considered in this paper. This problem is first converted to a high-resolution frequency estimation problem. Then, the sample lagged covariance matrices of the resulting signal are computed and studied in terms of their eigenstructure. These matrices are shown to be as effective in extracting bases for the signal and noise subspaces as the standard autocorrelation matrix, which is normally used in MUSIC and the pencil-based methods. Frequency estimators are then derived using these subspaces. The effectiveness of the method is demonstrated on two examples: a standard frequency estimation problem in presence of colored noise and a real-world problem that involves separation of multiple specular components from the acoustic backscattered from an underwater target.This work was supported by the Office of Naval Research (ONR 321TS). The Technical Agent was Coastal Systems Station, Panama City, FL

    Underwater target detection using multichannel subband adaptive filtering and high-order correlation schemes

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    Includes bibliographical references.In this paper, new pre- and post-processing schemes are developed to process shallow-water sonar data to improve the accuracy of target detection. A multichannel subband adaptive filtering is applied to preprocess the data in order to isolate the potential target returns from the acoustic backscattered signals and improve the signal-to-reverberation ratio. This is done by estimating the time delays associated with the reflections in different subbands. The preprocessed results are then beamformed to generate an image for each ping of the sonar. The testing results on both the simulated and real data revealed the efficiency of this scheme in time-delay estimation and its capability in removing most of the competing reverberations and noise. To improve detection rate while significantly minimizing the incident of false detections, a high-order correlation (HOC) method for postprocessing the beamformed images is then developed. This method determines the consistency in occurrence of the target returns in several consecutive pings. The application of the HOC process to the real beamformed sonar data showed the ability of this method for removing the clutter and at the same time boosting the target returns in several consecutive pings. The algorithm is simple, fast, and easy to implement.This work was supported by the Office of Naval Research (ONR 321TS) under Contract N61331-94-K-0018

    Looking for leakage or monitoring for public assurance?

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    Monitoring is a regulatory requirement for all carbon dioxide capture and geological storage (CCS) projects to verify containment of injected carbon dioxide (CO2) within a licensed geological storage complex. Carbon markets require CO2 storage to be verified. The public wants assurances CCS projects will not cause any harm to themselves, the environment or other natural resources. In the unlikely event that CO2 leaks from a storage complex, and into groundwater, to the surface, atmosphere or ocean, then monitoring methods will be required to locate, assess and quantify the leak, and to inform the community about the risks and impacts on health, safety and the environment. This paper considers strategies to improve the efficiency of monitoring the large surface area overlying onshore storage complexes. We provide a synthesis of findings from monitoring for CO2 leakage at geological storage sites both natural and engineered, and from monitoring controlled releases of CO2 at four shallow release facilities – ZERT (USA), Ginninderra (Australia), Ressacada (Brazil) and CO2 field lab (Norway)

    Targeted p120-Catenin Ablation Disrupts Dental Enamel Development

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    Dental enamel development occurs in stages. The ameloblast cell layer is adjacent to, and is responsible for, enamel formation. When rodent pre-ameloblasts become tall columnar secretory-stage ameloblasts, they secrete enamel matrix proteins, and the ameloblasts start moving in rows that slide by one another. This movement is necessary to form the characteristic decussating enamel prism pattern. Thus, a dynamic system of intercellular interactions is required for proper enamel development. Cadherins are components of the adherens junction (AJ), and they span the cell membrane to mediate attachment to adjacent cells. p120 stabilizes cadherins by preventing their internalization and degradation. So, we asked if p120-mediated cadherin stability is important for dental enamel formation. Targeted p120 ablation in the mouse enamel organ had a striking effect. Secretory stage ameloblasts detached from surrounding tissues, lost polarity, flattened, and ameloblast E- and N-cadherin expression became undetectable by immunostaining. The enamel itself was poorly mineralized and appeared to be composed of a thin layer of merged spheres that abraded from the tooth. Significantly, p120 mosaic mouse teeth were capable of forming normal enamel demonstrating that the enamel defects were not a secondary effect of p120 ablation. Surprisingly, blood-filled sinusoids developed in random locations around the developing teeth. This has not been observed in other p120-ablated tissues and may be due to altered p120-mediated cell signaling. These data reveal a critical role for p120 in tooth and dental enamel development and are consistent with p120 directing the attachment and detachment of the secretory stage ameloblasts as they move in rows
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