Molecular gas freeze-out in the pre-stellar core L1689B

C17O (J=2-1) observations have been carried out towards the pre-stellar core L1689B. By comparing the relative strengths of the hyperfine components of this line, the emission is shown to be optically thin. This allows accurate CO column densities to be determined and, for reference, this calculation is described in detail. The hydrogen column densities that these measurements imply are substantially smaller than those calculated from SCUBA dust emission data. Furthermore, the C17O column densities are approximately constant across L1689B whereas the SCUBA column densities are peaked towards the centre. The most likely explanation is that CO is depleted from the central regions of L1689B. Simple models of pre-stellar cores with an inner depleted region are compared with the results. This enables the magnitude of the CO depletion to be quantified and also allows the spatial extent of the freeze-out to be firmly established. We estimate that within about 5000 AU of the centre of L1689B, over 90% of the CO has frozen onto grains. This level of depletion can only be achieved after a duration that is at least comparable to the free-fall timescale.Comment: MNRAS letters. 5 pages, 5 figure

Surface electrical properties experiment, part 1

The work is reported which was performed on the Surface Electrical Properties Experiment Data Acquisition System. Areas discussed include: data handling and processing, installation and external signal application, operation of the equipment, and digital output. Detailed circuit descriptions are included

Prediction of unsteady aerodynamic loadings caused by leading edge and trailing edge control surface motions in subsonic compressible flow: Analysis and results

A theoretical analysis and computer program was developed for the prediction of unsteady lifting surface loadings caused by motions of leading edge and trailing edge control surfaces having sealed gaps. The final form of the downwash integral equation was formulated by isolating the singularities from the nonsingular terms and using a preferred solution process to remove and evaluate the downwash discontinuities in a systematic manner. Comparisons of theoretical and experimental pressure data are made for several control surface configurations. The comparisons indicate that reasonably accurate theoretical pressure distributions and generalized forces may be obtained for a wide variety of control surface configurations. Spanwise symmetry or antisymmetry of motion, and up to six control surfaces on each half span can be accommodated

Deep Halpha imagery of the Eridanus shells

A deep \ha image of interlocking filamentary arcs of nebulosity has been obtained with a wide-field ($\approx$ 30\degree diameter) narrow-band filter camera combined with a CCD as a detector. The resultant mosaic of images, extending to a galactic latitude of 65$^{o}$, has been corrected for field distortions and had galactic coordinates superimposed on it to permit accurate correlations with the most recent H{\sc i} (21 cm), X-ray (0.75 kev) and FIR (IRAS 100 $\mu$m) maps. Furthermore, an upper limit of 0.13 arcsec/yr to the expansion proper motion of the primary 25\degree long nebulous arc has been obtained by comparing a recent \ha image obtained with the San Pedro Martir telescope of its filamentary edge with that on a POSS E plate obtained in 1951. It is concluded that these filamentary arcs are the superimposed images of separate shells (driven by supernova explosions and/or stellar winds) rather than the edges of a single `superbubble' stretching from Barnard's Arc (and the Orion Nebula) to these high galactic latitudes. The proper motion measurement argues against the primary \ha emitting arc being associated with the giant radio loop (Loop 2) except in extraordinary circumstances.Comment: 9 pages, 5 figures, accepted for MNRAS publicatio

Yellow Perch Population Assessment in Southwestern Lake Michigan July 1, 2013 – June 30, 2014

Reports on progress and results of the following study objectives: monitor the adult yellow perch population on a seasonal basis; determine the age composition of angler-caught yellow perch; sample demersal age-0 yellow perch and their food resources in nearshore waters; sample juvenile (age-0 through age-3) yellow perch in nearshore waters; survey nearshore substrate with a focus on historical yellow perch spawning grounds; data analysis and report preparation.Illinois Department of Natural Resources Division of Fisheries F-123-R-20unpublishednot peer reviewedOpe

Yellow Perch Population Assessment in Southwestern Lake Michigan July 1, 2011 – June 30, 2012

Reports on progress and results for the following project objectives: Improve annual assessments of the yellow perch spawning population, spring spawning assessment; Improve annual assessments of the yellow perch spawning population, fall assessment; Develop angler-caught age and sex distribution; Sample pelagic age-0 yellow perch and their food resources in offshore waters; Sample demersal age-0 yellow perch and their food resources in nearshore waters; Sample juvenile (age-0 through age-2) yellow perch in nearshore waters; Data analysis and report preparation.Illinois Department of Natural Resources, Division of Fisheries F-123-R-18unpublishednot peer reviewedOpe

The Immunomodulatory Role of Syncytiotrophoblast Microvesicles

Immune adaptation is a critical component of successful pregnancy. Of primary importance is the modification of cytokine production upon immune activation. With the discovery that normal pregnancy itself is a pro-inflammatory state, it was recognised that the classical Th1/Th2 cytokine paradigm, with a shift towards ‘type 2’ cytokine production (important for antibody production), and away from ‘type 1’ immunity (associated with cell mediated immunity and graft rejection), is too simplistic. It is now generally agreed that both arms of cytokine immunity are activated, but with a bias towards ‘type 2’ immunity. Many factors are released from the placenta that can influence the maternal cytokine balance. Here we focus on syncytiotrophoblast microvesicles (STBM) which are shed from the placenta into the maternal circulation. We show that STBM can bind to monocytes and B cells and induce cytokine release (TNFα, MIP-1α, IL-1α, IL-1β, IL-6, IL-8). Other cytokines are down-modulated, such as IP-10 which is associated with ‘type 1’ immunity. Therefore STBM may aid the ‘type 2’ skewed nature of normal pregnancy. We also observed that PBMC from third trimester normal pregnant women produce more TNFα and IL-6 in response to STBM than PBMC from non-pregnant women, confirming that maternal immune cells are primed by pregnancy, possibly through their interaction with STBM