Injerto autólogo cubital como complemento a una mandibulectomía parcial para el tratamiento de un tumor de células escamosas

Se presenta un caso clínico de un tumor de células escamosas en la cavidad oral del perro, resuelto mediante mandibulectomía parcial combinada con la implantación de un injerto óseo autólogo. En la evolución tras 30 meses no ha presentado recidivas ni metástasis

Pliocene sigmodontine rodents (Mammalia: Cricetidae) in northernmost South America: test of biogeographic hypotheses and revised evolutionary scenarios

We document the first occurrence of Sigmodontinae (Mammalia, Rodentia, Cricetidae) from the Pliocene of northern South America, from the San Gregorio Formation of northwestern Venezuela. The recovered isolated molars are identified as Oligoryzomys sp. and Zygodontomys sp., two currently widespread sigmodontines in South America. These records constitute the oldest representatives of these genera, potentially new species, and the first Pliocene occurrence for Oryzomyini and the whole subfamily outside Argentina. Hypotheses on the historical biogeography of sigmodontines have been constructed almost exclusively using genetic data and the fossils we report provide a new kind of evidence. The occurrence of Oligoryzomys sp. and Zygodontomys sp. in Venezuela provides novel information for the diversification models suggested for Oligoryzomys, by supporting a potential eastern corridor of open environments from northern to southern South America. The presence of sigmodontines from the locality home of the new reports, Norte Casa Chiguaje, is consistent with the palaeoenvironmental conditions originally proposed for it based on mammals and botanical records, being characterized as mixed open grassland/forest areas surrounding permanent freshwater systems. The new sigmodontine evidence is used to discuss the putative scenarios of the ancient evolution of the subfamily in South America, favouring a model in which open areas (savannahs) to the east of the Andes played crucial role aiding or obstructing Late Miocene-Pliocene sigmodontine dispersion southwards

Sources of Cosmic Dust in the Earth's Atmosphere

There are four known sources of dust in the inner solar system: Jupiter Family comets, Asteroids, Halley Type comets, and Oort Cloud comets. Here we combine the mass, velocity and radiant distributions of these cosmic dust populations from an astronomical model with a chemical ablation model to estimate the injection rates of Na and Fe into the Earth's upper atmosphere, as well as the flux of cosmic spherules to the surface. Comparing these parameters to lidar observations of the vertical Na and Fe fluxes above 87.5 km, and the measured cosmic spherule accretion rate at South Pole, shows that Jupiter Family Comets contribute (80 ± 17) % of the total input mass (43 ± 14 t d¯¹), in good accord with COBE and Planck observations of the Zodiacal Cloud

Crocodylian diversity peak and extinction in the late Cenozoic of the northern Neotropics

Northern South America and South East Asia are today’s hotspots of crocodylian diversity with up to six (mainly alligatorid) and four (mainly crocodylid) living species respectively, of which usually no more than two or three occur sympatrically. In contrast, during the late Miocene, 14 species existed in South America. Here we show a diversity peak in sympatric occurrence of at least seven species, based on detailed stratigraphic sequence sampling and correlation, involving four geological formations from the middle Miocene to the Pliocene, and on the discovery of two new species and a new occurrence. This degree of crocodylian sympatry is unique in the world and shows that at least several members of Alligatoroidea and Gavialoidea coexisted. By the Pliocene, all these species became extinct, and their extinction was probably related to hydrographic changes linked to the Andean uplift. The extant fauna is first recorded with the oldest Crocodylus species from South America.Facultad de Ciencias Naturales y Muse

Association of Motivational Climate With Addictive Behaviors Depending on Type of Sport in University Students: Structural Equation Analysis

This research study aims at contrasting a structural model of the associations between the alcohol consumption, tobacco dependence, and the problematic use of video games with motivational climate toward sport depending on the category of sports practiced in a sample of Physical Education university students. The sample consisted of 775 university students from the Autonomous Community of Andalusia (Spain), aged between 21 and 35 (22.22 ± 3.76) years. The instruments used were the Perceived Motivational Climate in Sport Questionnaire (PMCSQ-2), the Alcohol Use Disorders Identification Test (AUDIT), the Fagerström Test for Nicotine Dependence (FTND), and the Questionnaire of Experiences Related to Video Games (QERV) questionnaires. A path model that fitted properly in the multigroup analysis for both categories of sports was used, χ2 = 19.843; gl = 8; p = .011; comparative fit index (CFI) = 0.911; normed fit index (NFI) = 0.903; incremental fit index (IFI) = 0.912; root mean square error approximation (RMSEA) = 0.085. An inverse association was shown between task climate and tobacco consumption in individual sports, being weaker in collective sports. This association is not significant for collective sports, but it is for individual sports for ego climate. However, a positive association was found between ego climate and the use of video games in individual sports, not being significant in the case of collective sports. The importance of promoting motivational climates oriented toward tasks that are based on the practice of collective sports is established, because they could act as protective factors against the development of addictive behavior in university students.This research study has been supported by the Education Innovation Project PID 16-45, named “Implementation of digital resources in the classroom for the development of psychosocial and motivational factors in students of the degree in Primary Education with the speciality in Physical Education,” funded by the University of Granada. Education Innovation Project PIBD Advanced 470, named “Program of teaching intervention in students of the degree in primary education and early childhood education through the use of new technologies for the improvement of the psychosocial factors of the students,” funded by the University of Granada. Project I+D+I “DISPERSA,” with code number TIN2015-67149-C3-R, named “Design of Pervasive Games Based on Learning Experiences Sensitive to Context” funded by the Ministry of Economy and Competitiveness. Precompetitive Research Projects for Young Researchers (PPJI_B-05); Self-plan Research of the University of Granada

Effectiveness of individualized inhaler technique training on low adherence (LowAd) in ambulatory patients with COPD and asthma

© 2022. This document is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by /4.0/ This document is the published version of a published work that appeared in final form in npj primary care respiratory medicineTo analyze whether there is improvement in adherence to inhaled treatment in patients with COPD and asthma after an educational intervention based on the teach-to-goal method. This is a prospective, non-randomized, single-group study, with intervention and before-after evaluation. The study population included 120 patients (67 females and 53 males) diagnosed with asthma (70.8%) and COPD (29.1%). The level of adherence (low and optimal) and the noncompliance behavior pattern (erratic, deliberate and unwitting) were determined by the Test of the adherence to Inhalers (TAI). This questionnaire allows you to determine the level of adherence and the types of noncompliance. Low Adherence (LowAd) was defined as a score less than 49 points. All patients received individualized educational inhaler technique intervention (IEITI). Before the IEITI, 67.5% of the patients had LowAd. Following IEITI, on week 24, LowAd was 55% (p = 0.024). Each patient can present one or more types of noncompliance. The most frequent type was forgetting to use the inhaler (erratic), 65.8%. The other types were deliberate: 43.3%, and unwitting: 57.5%. All of them had decreased on the final visit: 51.7% (p = 0.009), 25.8% (p = 0.002), 39.2% (p = 0.002). There were no significant differences in adherence between asthma and COPD patients at the start of the study. The only predicting factor of LowAd was the female gender. An individualized educational intervention, in ambulatory patients with COPD and asthma, in real-world clinical practice conditions, improves adherence to the inhaled treatment

Novel Experimental Simulations of the Atmospheric Injection of Meteoric Metals

A newly developed laboratory, Meteoric Ablation Simulator (MASI), is used to test model predictions of the atmospheric ablation of interplanetary dust particles (IDPs) with experimental Na, Fe, and Ca vaporization profiles. MASI is the first laboratory setup capable of performing time-resolved atmospheric ablation simulations, by means of precision resistive heating and atomic laser-induced fluorescence detection. Experiments using meteoritic IDP analogues show that at least three mineral phases (Na-rich plagioclase, metal sulfide, and Mg-rich silicate) are required to explain the observed appearance temperatures of the vaporized elements. Low melting temperatures of Na-rich plagioclase and metal sulfide, compared to silicate grains, preclude equilibration of all the elemental constituents in a single melt. The phase-change process of distinct mineral components determines the way in which Na and Fe evaporate. Ca evaporation is dependent on particle size and on the initial composition of the molten silicate. Measured vaporized fractions of Na, Fe, and Ca as a function of particle size and speed confirm differential ablation (i.e., the most volatile elements such as Na ablate first, followed by the main constituents Fe, Mg, and Si, and finally the most refractory elements such as Ca). The Chemical Ablation Model (CABMOD) provides a reasonable approximation to this effect based on chemical fractionation of a molten silicate in thermodynamic equilibrium, even though the compositional and geometric description of IDPs is simplistic. Improvements in the model are required in order to better reproduce the specific shape of the elemental ablation profiles

Selective Disparity of Ordinary Chondritic Precursors in Micrometeorite Flux

All known extraterrestrial dust (micrometeoroids) entering the Earth's atmosphere is anticipated to have a significant contribution from ordinary chondritic precursors, as seen in meteorites, but this is an apparent contradiction that needs to be addressed. Ordinary chondrites represent a minor contribution to the overall meteor influx compared to carbonaceous chondrites, which are largely dominated by CI and/or CM chondrites. However, the near-Earth asteroid population presents a scenario with sufficient scope for generation of dust-sized debris from ordinary chondritic sources. The bulk chemical composition of 3255 micrometeorites (MMs) collected from Antarctica and deep-sea sediments has shown Mg/Si largely dominated by carbonaceous chondrites, and less than 10% having ordinary chondritic precursors. The chemical ablation model is combined with different initial chondritic compositions (CI, CV, L, LL, H), and the results clearly indicate that high-density (≥2.8 g cm⁻³) precursors, such as CV and ordinary chondrites in the size range 100–700 μm and zenith angle 0°–70°, ablate at much faster rates and lose their identity even before reaching the Earth's surface and hence are under-represented in our collections. Moreover, their ability to survive as MMs remains grim for high-velocity micrometeoroids (>16 km s⁻¹). The elemental ratio for CV and ordinary chondrites are also similar to each other irrespective of the difference in the initial chemical composition. In conclusion, MMs belonging to ordinary chondritic precursors' concentrations may not be insignificant in thermosphere, as they are found on Earth's surface

On the size and velocity distribution of cosmic dust particles entering the atmosphere

The size and velocity distribution of cosmic dust particles entering the Earth's atmosphere is uncertain. Here we show that the relative concentrations of metal atoms in the upper mesosphere, and the surface accretion rate of cosmic spherules, provide sensitive probes of this distribution. Three cosmic dust models are selected as case studies: two are astronomical models, the first constrained by infrared observations of the Zodiacal Dust Cloud and the second by radar observations of meteor head echoes; the third model is based on measurements made with a spaceborne dust detector. For each model, a Monte Carlo sampling method combined with a chemical ablation model is used to predict the ablation rates of Na, K, Fe, Mg, and Ca above 60 km and cosmic spherule production rate. It appears that a significant fraction of the cosmic dust consists of small (<5 µg) and slow (<15 km s−1) particles