Voici le groupe du personnel du Messager [Article]

Undated article clipping from Le Messager identifying some of the staff of 1928: Elmyra Tremblay, Albert Bédard Philibert Buteau, Edmond Martin, Yvonne Blais, Dominique Dionne, F. X. Guay, Louis-Philippe Gagné. Valdor-L. Couture, Jean-Baptiste Couture, Faust Couture, Adélard Roy, Omer Gauvin, Liane Michaud (Mme. Gérard Marcotte), Fernand Martin, Irma Poirier (Mme. J.-Raoul Plante), Léonard Michaud, J.-E.-N. Bohémier, Mme. Henri F. Roy (Loretta Vachon), Eugène Gélinas, Delia DeBlois (Mme Flavius Dionne), and Joseph Girard.https://digitalcommons.usm.maine.edu/le-messager/1016/thumbnail.jp

Artificial (METALLO-) enzymes: Design and application

The catalytic efficiency and high selectivities achieved by natural metalloenzymes are a source of inspiration for the design of novel bio inspired catalysts. A powerful approach for creating artificial metalloenzymes involves incorporating a synthetic transition metal catalysts into a biomolecular scaffold such as a protein or DNA. We have developed a new concept for the design of artificial metalloenzymes that involves creation of a novel active site at the dimer interface of the transcription factor LmrR (Lactococcal multidrug resistance Regulator) [1]. LmrR was selected as the protein scaffold because it contains an unusual large hydrophobic pocket on the dimer interface. Here, two novel classes of LmrR-based artificial metalloenzymes will be presented, involving either supramolecular anchoring of the metal complex[2] or biosynthetic incorporation of an unnatural metal binding amino acid using expanded genetic code methodology [3]. These artificial metalloenzymes have been applied successfully in catalytic asymmetric C-C bond forming and hydration reactions. Finally, our recent insights into how to design the second coordination sphere will be discussed. 1. J. Bos, F. Fusetti, A.J.M. Driessen and G. Roelfes, Angew. Chem. Int. Ed., 2012, 51, 7472-7475. 2. J. Bos, W.R. Browne, A.J.M. Driessen and G. Roelfes, J. Am. Chem. Soc., 2015, 137, 9796–9799. 3. I. Drienovská, A. Rioz-Martínez, A. Draksharapu and G. Roelfes, Chem. Sci., 2015, 6, 770-776. 4. M. Bersellini and G. Roelfes, Org. Biomol. Chem., 2017, DOI: 10.1039/C7OB00390

Chandra Observation of an X-ray Flare at Saturn: Evidence for Direct Solar Control on Saturn's Disk X-ray Emissions

Saturn was observed by Chandra ACIS-S on 20 and 26-27 January 2004 for one full Saturn rotation (10.7 hr) at each epoch. We report here the first observation of an X-ray flare from Saturn's non-auroral (low-latitude) disk, which is seen in direct response to an M6-class flare emanating from a sunspot that was clearly visible from both Saturn and Earth. Saturn's disk X-ray emissions are found to be variable on time scales of hours to weeks to months, and correlated with solar F10.7 cm flux. Unlike Jupiter, X-rays from Saturn's polar (auroral) region have characteristics similar to those from its disk. This report, combined with earlier studies, establishes that disk X-ray emissions of the giant planets Saturn and Jupiter are directly regulated by processes happening on the Sun. We suggest that these emissions could be monitored to study X-ray flaring from solar active regions when they are on the far side and not visible to Near-Earth space weather satellites.Comment: Total 12 pages including 4 figure

Importants avenços en l'estudi de proteïnes transportadores de membrana

Investigadors de la Unitat de Biofísica del Departament de Bioquímica i de Biologia Molecular, membres del Centre d'Estudis en Biofísica de la UAB, han publicat tres importants articles sobre el funcionament de proteïnes transportadores de membrana. Els treballs, dirigits pel Dr. Esteve Padrós, s'han realitzat en col·laboració i s'han publicat a les prestigioses revistes Angew. Chem.; J. Amer. Chem. Soc.; Proc. Natl. Acad. Sci. USA.Investigadores de la Unidad de Biofísica del Departamento de Bioquímica y Biología Molecular, miembros del Centro de Estudios en Biofísica de la UAB, han publicado tres importantes artículos sobre el funcionamiento de proteínas transportadoras de membrana. Los trabajos, dirigidos por el Dr. Esteve Padrós, se han realizado en colaboración y se han publicado en las prestigiosas revistas Angew. Chem.; J. Amer. Chem. Soc.; y Proc. Natl. Acad. Sci. USA.Researchers at the Biophysics Unit of the Department of Biochemistry and Molecular Biology, members of the UAB Center for Biophysical Studies, have published three leading articles on the functioning of membrane transport proteins. The works, led by Dr. Esteve Padrós were carried out in collaboration and have been published in the prestigious journals Angew. Chem., J. Amer. Chem. Soc., and Proc. Natl. Acad. Sci. USA

Compte rendu de : A history of Nepal / J. Whelpton, Cambridge University Press, 2005

In : CNAS, vol.32, n°

“Little Soldiers with Big Guns”: The Language of Child-Soldiering in Africa

This project examines the language of child-soldiering in Africa, specifically in Sierra Leone, Rwanda, and Uganda, comparing its use between Western observers and the Africans who experienced the conflict first hand. It concludes that Westerners unilaterally display ethnocentric conceptions of the sanctity of childhood in their admonitions of child-soldiering, while former child-soldiers, perpetrators, victims and local aid workers exhibit more diverse perspectives that more accurately reflect the complexity of the conflicts. Furthermore, it concludes that the use of rhetorical, monolithic language regarding child-soldiering perpetuates stereotypes about African conflict and state-failure while diverting attention from underlying root causes of conflict, and overlooks government corruption and human rights abuses that have gone largely unchecked by Western nations despite their condemnation of the violence

The Rhetorical Algorithm: WikiLeaks and the Elliptical Secrets of Donald J. Trump

Algorithms were a generative force behind many of the leaks and secrets that dominated the 2016 election season. Taking the form of the identity-anonymizing Tor software that protected the identity of leakers, mathematical protocols occupied a prominent place in the secrets generated during the presidential campaign. This essay suggests that the rhetorical trope of ellipsis offers an equally crucial, algorithmic formula for explaining the public production of these secrets and leaks. It then describes the 2016 DNC leak and Donald Trump’s “I love Wikileaks” moment using the trope of ellipsis, which marks a discursive omission or gap in official executive discourse

Sound Icon, Inaugural Concert: Acoustic Spaces, March 26, 2011

This is the concert program of the Sound Icon, Inaugural Concert: Acoustic Spaces performance on Saturday, March 26, 2011 at 8:00 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts. Works performed were Fata Morgana by Davide Ianni, Receil de pierre de sable by Joshua Fineberg, and Les Espaces Acoustiques by Gérard Grisey. Digitization for Boston University Concert Programs was supported by the Boston University Center for the Humanities Library Endowed Fund

Hop and HipHop : Multitier Web Orchestration

Rich applications merge classical computing, client-server concurrency, web-based interfaces, and the complex time- and event-based reactive programming found in embedded systems. To handle them, we extend the Hop web programming platform by HipHop, a domain-specific language dedicated to event-based process orchestration. Borrowing the synchronous reactive model of Esterel, HipHop is based on synchronous concurrency and preemption primitives that are known to be key components for the modular design of complex reactive behaviors. HipHop departs from Esterel by its ability to handle the dynamicity of Web applications, thanks to the reflexivity of Hop. Using a music player example, we show how to modularly build a non-trivial Hop application using HipHop orchestration code.Comment: International Conference on Distributed Computing and Internet Technology (2014