COSMIC: Combustion Synthesis under Microgravity Conditions

The results of experiments conducted to study combustion synthesis under given microgravity conditions are presented. Self-propagating combustion synthesis processes involve several stages that are significantly affected by gravity: melting of reactants and products, and densification of liquid products. The results show that the addition of inert reactants leads to heat substraction and to a decrease in combustion temperature. Combustion front quenching experiments revealed that the extinction of the combustion wave occurred earlier in microgravity

The Use of Ion Mobility Mass Spectrometry for Isomer Composition Determination Extracted from Se-Rich Yeast

peer reviewedThe isomer ratio determination of a selenium-containing metabolite produced by Se-rich yeast was performed. Electrospray Ionization and Ion Mobility Mass Spectrometry (IM-MS) were unsuccessfully used in order to resolve the isomers according to their Collisional Cross Section (CCS) difference. The isomer ratio determination of 2,3-dihydroxypropionylselenocystathionine was performed after multidimensional liquid chromatography preconcentration from a water extract of Se-rich yeast using preparative size exclusion, anion exchange and capillary reverse phase columns coupled to IM-MS. 4’-nitrobenzo-15-crown-5 ether, a Selective Shift Reagent (SSR), was added after the last chromatographic dimension in order to specifically increase the CCS of one of the isomers by the formation of a stable host-guest system with the crown-ether . Both isomers were consequently fully resolved by IM-MS and the relative ratio of the isomers was determined: 11-13% and 87-89%. The present data compared favorably with literature to support the analytical strategy despite the lack of authentic standard for method validation. In addition, computational chemistry methods were successfully applied to design the SSR and to support the experimental data