179 research outputs found
Near threshold eta meson production in the d+d->alpha+eta reaction
The d+d->alpha+eta reaction has been investigated near threshold using the
ANKE facility at COSY-Juelich. Both total and differential cross sections have
been measured at two excess energies, Q=2.6 MeV and 7.7 MeV, with a
subthreshold measurement being undertaken at Q=-2.6 MeV to study the physical
background. While consistent with isotropy at the lower energy, the angular
distribution reveals a pronounced anisotropy at the higher one, indicating the
presence of higher partial waves. Options for the decomposition into partial
amplitudes and their consequences for determination of the s-wave eta-alpha
scattering length are discussed.Comment: 8pp, fig.3 added, normalisation in eq.4.1 correcte
Deuteron-deuteron collision at 160 MeV
The experiment was carried out using BINA detector at KVI in Groningen. For
the first time an extensive data analysis of the data collected in back part of
the detector is presented, where a clusterization method is utilized for
angular and energy information. We also present differential cross-sections for
the (dddpn) breakup reaction within \textit{dp} quasi-free
scattering limit and their comparison with first calculations based on Single
Scattering Approximation (SSA) approach.Comment: 6 pages, 4 figures, presented at Jagiellonian Symposium 2015 in
Krakow, PhD wor
Leadership training to improve adenoma detection rate in screening colonoscopy: A randomised trial
Objective Suboptimal adenoma detection rate (ADR) at colonoscopy is associated with increased risk of interval colorectal cancer. It is uncertain how ADR might be improved. We compared t
Investigating A Dose Response Relationship between High Fat Diet Consumption and the Contractile Performance of Isolated Mouse Soleus, EDL and Diaphragm Muscles
The influence of CYP2D6 and CYP2C19 genetic variation on diabetes mellitus risk in people taking antidepressants and antipsychotics
CYP2D6 and CYP2C19 enzymes are essential in the metabolism of antidepressants and antipsychotics. Genetic variation in these genes may increase risk of adverse drug reactions. Antidepressants and antipsychotics have previously been associated with risk of diabetes. We examined whether individual genetic differences in CYP2D6 and CYP2C19 contribute to these effects. We identified 31,579 individuals taking antidepressants and 2699 taking antipsychotics within UK Biobank. Participants were classified as poor, intermediate, or normal metabolizers of CYP2D6, and as poor, intermediate, normal, rapid, or ultra-rapid metabolizers of CYP2C19. Risk of diabetes mellitus represented by HbA1c level was examined in relation to the metabolic phenotypes. CYP2D6 poor metabolizers taking paroxetine had higher Hb1Ac than normal metabolizers (mean difference: 2.29 mmol/mol; p < 0.001). Among participants with diabetes who were taking venlafaxine, CYP2D6 poor metabolizers had higher HbA1c levels compared to normal metabolizers (mean differences: 10.15 mmol/mol; p < 0.001. Among participants with diabetes who were taking fluoxetine, CYP2D6 intermediate metabolizers and decreased HbA1c, compared to normal metabolizers (mean difference −7.74 mmol/mol; p = 0.017). We did not observe any relationship between CYP2D6 or CYP2C19 metabolic status and HbA1c levels in participants taking antipsychotic medication. Our results indicate that the impact of genetic variation in CYP2D6 differs depending on diabetes status. Although our findings support existing clinical guidelines, further research is essential to inform pharmacogenetic testing for people taking antidepressants and antipsychotics
Search for eta-mesic 4He in the dd->3He n pi0 and dd->3He p pi- reactions with the WASA-at-COSY facility
The search for 4He-eta bound states was performed with the WASA-at-COSY
facility via the measurement of the excitation function for the dd->3He n pi0
and dd->3He p pi- processes. The beam momentum was varied continuously between
2.127 GeV/c and 2.422 GeV/c, corresponding to the excess energy for the dd->4He
eta reaction ranging from Q=-70 MeV to Q=30 MeV. The luminosity was determined
based on the dd->3He n reaction and quasi-free proton-proton scattering via
dd->pp n_spectator n_spectator reactions. The excitation functions determined
independently for the measured reactions do not reveal a structure which could
be interpreted as a narrow mesic nucleus. Therefore, the upper limits of the
total cross sections for the bound state production and decay in
dd->(4He-eta)_bound->3He n pi0 and dd->(4He-eta)_bound->3He p pi- processes
were determined taking into account the isospin relation between both the
channels considered. The results of the analysis depend on the assumptions of
the N* momentum distribution in the anticipated mesic-4He. Assuming as in the
previous works, that this is identical with the distribution of nucleons bound
with 20 MeV in 4He, we determined that (for the mesic bound state width in the
range from 5 MeV to 50 MeV) the upper limits at 90% confidence level are about
3 nb and about 6 nb for npi0 and ppi- channels, respectively. However, based on
the recent theoretical findings of the N*(1535) momentum distribution in the
N*-3He nucleus bound by 3.6 MeV, we find that the WASA-at-COSY detector
acceptance decreases and hence the corresponding upper limits are 5 nb and 10
nb for npi0 and ppi- channels respectively.Comment: This article will be submitted to JHE
Cross section ratio and angular distributions of the reaction p + d -> 3He + eta at 48.8 MeV and 59.8 MeV excess energy
We present new data for angular distributions and on the cross section ratio
of the p + d -> 3He + eta reaction at excess energies of Q = 48.8 MeV and Q =
59.8 MeV. The data have been obtained at the WASA-at-COSY experiment
(Forschungszentrum J\"ulich) using a proton beam and a deuterium pellet target.
While the shape of obtained angular distributions show only a slow variation
with the energy, the new results indicate a distinct and unexpected total cross
section fluctuation between Q = 20 MeV and Q = 60 MeV, which might indicate the
variation of the production mechanism within this energy interval.Comment: 9 pages, 9 figure
Search for the eta-mesic 4He with WASA-at-COSY detector
An exclusive measurement of the excitation function for the dd->3Heppi-
reaction was performed at the Cooler Synchrotron COSY-Juelich with the
WASA-at-COSY detection system. The data were taken during a slow acceleration
of the beam from 2.185 GeV/c to 2.400 GeV/c crossing the kinematic threshold
for the eta meson production in the dd->4He-eta reaction at 2.336 GeV/c. The
corresponding excess energy with respect to the 4He-eta system varied from
-51.4MeV to 22MeV. The integrated luminosity in the experiment was determined
using the dd->3Hen reaction. The shape of the excitation function for the
dd->3Heppi- was examined. No signal of the 4He-eta bound state was observed. An
upper limit for the cross-section for the bound state formation and decay in
the process dd->(4He-eta)bound->3Heppi- was determined on the 90% confidence
level and it varies from 20nb to 27nb for the bound state width ranging from
5MeV to 35MeV, respectively.Comment: 8 pages, 9 figure
- …