Renormalization effects on neutrino masses and mixing in a string-inspired SU(4) X SU(2)_L X SU(2)_R X U(1)_X model

We discuss renormalization effects on neutrino masses and mixing angles in a supersymmetric string-inspired SU(4) X SU(2)_L X SU(2)_R X U(1)_X model, with matter in fundamental and antisymmetric tensor representations and singlet Higgs fields charged under the anomalous U(1)_X family symmetry. The quark, lepton and neutrino Yukawa matrices are distinguished by different Clebsch-Gordan coefficients. The presence of a second U(1)_X breaking singlet with fractional charge allows a more realistic, hierarchical light neutrino mass spectrum with bi-large mixing. By numerical investigation we find a region in the model parameter space where the neutrino mass-squared differences and mixing angles at low energy are consistent with experimental data.Comment: 9 pages, 7 figures; references adde

secCl is a cys-loop ion channel necessary for the chloride conductance that mediates hormone-induced fluid secretion in Drosophila

Organisms use circulating diuretic hormones to control water balance (osmolarity), thereby avoiding dehydration and managing excretion of waste products. The hormones act through G-protein-coupled receptors to activate second messenger systems that in turn control the permeability of secretory epithelia to ions like chloride. In insects, the chloride channel mediating the effects of diuretic hormones was unknown. Surprisingly, we find a pentameric, cys-loop chloride channel, a type of channel normally associated with neurotransmission, mediating hormone-induced transepithelial chloride conductance. This discovery is important because: 1) it describes an unexpected role for pentameric receptors in the membrane permeability of secretory epithelial cells, and 2) it suggests that neurotransmitter-gated ion channels may have evolved from channels involved in secretion

Comparing Segmentation by Time and by Motion in Visual Search: An fMRI Investigation

Abstract Brain activity was recorded while participants engaged in a difficult visual search task for a target defined by the spatial configuration of its component elements. The search displays were segmented by time (a preview then a search display), by motion, or were unsegmented. A preparatory network showed activity to the preview display, in the time but not in the motion segmentation condition. A region of the precuneus showed (i) higher activation when displays were segmented by time or by motion, and (ii) correlated activity with larger segmentation benefits behaviorally, regardless of the cue. Additionally, the results revealed that success in temporal segmentation was correlated with reduced activation in early visual areas, including V1. The results depict partially overlapping brain networks for segmentation in search by time and motion, with both cue-independent and cue-specific mechanisms.</jats:p

Primordial nucleosynthesis as a probe of fundamental physics parameters

We analyze the effect of variation of fundamental couplings and mass scales on primordial nucleosynthesis in a systematic way. The first step establishes the response of primordial element abundances to the variation of a large number of nuclear physics parameters, including nuclear binding energies. We find a strong influence of the n-p mass difference (for the 4He abundance), of the nucleon mass (for deuterium) and of A=3,4,7 binding energies (for 3He, 6Li and 7Li). A second step relates the nuclear parameters to the parameters of the Standard Model of particle physics. The deuterium, and, above all, 7Li abundances depend strongly on the average light quark mass hat{m} \equiv (m_u+m_d)/2. We calculate the behaviour of abundances when variations of fundamental parameters obey relations arising from grand unification. We also discuss the possibility of a substantial shift in the lithium abundance while the deuterium and 4He abundances are only weakly affected.Comment: v2: 34 pages, 2 figures, typo in last GUT scenario corrected, added discussion and graph of nonlinear behaviour in GUT scenarios, added short section discussing binding of dineutron and 8Be, refs added, conclusions unaltered. Accepted for publication, Phys. Rev.

Big bang nucleosynthesis as a probe of fundamental "constants"

Big Bang nucleosynthesis (BBN) is the earliest sensitive probe of the values of many fundamental particle physics parameters. We have found the leading linear dependences of primordial abundances on all relevant parameters of the standard BBN code, including binding energies and nuclear reaction rates. This enables us to set limits on possible variations of fundamental parameters. We find that 7Li is expected to be significantly more sensitive than other species to many fundamental parameters, a result which also holds for variations of coupling strengths in grand unified (GUT) models. Our work also indicates which areas of nuclear theory need further development if the values of ``constants'' are to be more accurately probed.Comment: Refereed article to be published in Nuclear Physics in Astrophysics III Proceedings, J. Phys. G. Special Issue. Based on work in collaboration with C. Wetterich (Heidelberg). 6 page

Fundamental constants and tests of general relativity - Theoretical and cosmological considerations

The tests of the constancy of the fundamental constants are tests of the local position invariance and thus of the equivalence principle. We summarize the various constraints that have been obtained and then describe the connection between varying constants and extensions of general relativity. To finish, we discuss the link with cosmology, and more particularly with the acceleration of the Universe. We take the opportunity to summarize various possibilities to test general relativity (but also the Copernican principle) on cosmological scales.Comment: Proceedings of the workshop ``The nature of gravity, confronting theory and experiment in space'', ISSI, Bern, october 200

Herschel evidence for disk flattening or gas depletion in transitional disks

Transitional disks are protoplanetary disks characterized by reduced near- and mid-infrared emission with respect to full disks. This characteristic spectral energy distribution indicates the presence of an optically thin inner cavity within the dust disk believed to mark the disappearance of the primordial massive disk. We present new Herschel Space Observatory PACS spectra of [OI] 63 micron for 21 transitional disks. Our survey complements the larger Herschel GASPS program "Gas in Protoplanetary Systems" (Dent et al. 2013) by quadrupling the number of transitional disks observed with PACS at this wavelength. [OI] 63 micron traces material in the outer regions of the disk, beyond the inner cavity of most transitional disks. We find that transitional disks have [OI] 63 micron line luminosities two times fainter than their full disk counterparts. We self consistently determine various stellar properties (e.g. bolometric luminosity, FUV excess, etc.) and disk properties (e.g. disk dust mass, etc.) that could influence the [OI] 63 micron line luminosity and we find no correlations that can explain the lower [OI] 63 micron line luminosities in transitional disks. Using a grid of thermo-chemical protoplanetary disk models, we conclude that either transitional disks are less flared than full disks or they possess lower gas-to-dust ratios due to a depletion of gas mass. This result suggests that transitional disks are more evolved than their full disk counterparts, possibly even at large radii.Comment: Accepted for publication in ApJ; 52 pages, 16 figures, 8 table

Eotvos bounds on couplings of fundamental parameters to gravity

The possible dependence of fundamental couplings and mass ratios on the gravitational potential has been bounded by comparing atomic clock frequencies over Earth's elliptical orbit. Here we evaluate bounds on such dependence from E"otv"os-type experiments that test the Weak Equivalence Principle, including previously neglected contributions from nuclear binding energy. We find that variations of fundamental parameters correlated with the gravitational potential are bounded at 10^-8--10^-9, an improvement of 2--3 orders of magnitude over atomic clock bounds.Comment: To be published (Phys.Rev.Lett.), minor changes and corrections, equivalent to journal versio

Processing and electromechanical properties of lanthanum-doped Pb(Zr,Ti)O3 extruded piezoelectric fibres

This article describes the processing and characterisation of lanthanum-doped lead zirconate titanate (PLZT)-based ferroelectric fibres for composite transducer applications. X-ray diffraction of the extruded and sintered fibres indicated some lead loss during sintering; however, the fibres exhibited low porosity (1.54%), high maximum piezoelectric strain (4041ppm) and relatively low coercive field (0.77kV/mm). The low coercive field of the lanthanum-doped fibres may be advantageous in terms of facilitating polarization of the fibres in composite architecture