93 research outputs found
Ecotoxicological effects of Dutch harbour sediments:The development of an effects-based assessment framework to regulate the disposal of dredged material in coastal waters of the Netherlands
HIRAX:A Probe of Dark Energy and Radio Transients
The Hydrogen Intensity and Real-time Analysis eXperiment (HIRAX) is a new
400-800MHz radio interferometer under development for deployment in South
Africa. HIRAX will comprise 1024 six meter parabolic dishes on a compact grid
and will map most of the southern sky over the course of four years. HIRAX has
two primary science goals: to constrain Dark Energy and measure structure at
high redshift, and to study radio transients and pulsars. HIRAX will observe
unresolved sources of neutral hydrogen via their redshifted 21-cm emission line
(`hydrogen intensity mapping'). The resulting maps of large-scale structure at
redshifts 0.8-2.5 will be used to measure Baryon Acoustic Oscillations (BAO).
HIRAX will improve upon current BAO measurements from galaxy surveys by
observing a larger cosmological volume (larger in both survey area and redshift
range) and by measuring BAO at higher redshift when the expansion of the
universe transitioned to Dark Energy domination. HIRAX will complement CHIME, a
hydrogen intensity mapping experiment in the Northern Hemisphere, by completing
the sky coverage in the same redshift range. HIRAX's location in the Southern
Hemisphere also allows a variety of cross-correlation measurements with
large-scale structure surveys at many wavelengths. Daily maps of a few thousand
square degrees of the Southern Hemisphere, encompassing much of the Milky Way
galaxy, will also open new opportunities for discovering and monitoring radio
transients. The HIRAX correlator will have the ability to rapidly and
eXperimentciently detect transient events. This new data will shed light on the
poorly understood nature of fast radio bursts (FRBs), enable pulsar monitoring
to enhance long-wavelength gravitational wave searches, and provide a rich data
set for new radio transient phenomena searches. This paper discusses the HIRAX
instrument, science goals, and current status.Comment: 11 pages, 5 figure
Oesterdam sand nourishment : Ecological and morphological development of a local sand nourishment
Relações interculturais na vida universitária: experiências de mobilidade internacional de docentes e discentes
Ecotoxicological effects of Dutch harbour sediments: The development of an effects-based assessment framework to regulate the disposal of dredged material in coastal waters of the Netherlands
Using the dioxin receptor-calux in vitro bioassay to screen marine harbor sediments for compounds with a dioxin-like mode of action
The presence of dioxin-like compounds in sediments from harbors and reference sites along the Dutch coast was investigated using the dioxin receptor–chemically activated luciferase gene expression (DR-CALUX) bioassay. The DR-CALUX response varied between 0.2 and 136 ng/kg dry weight expressed in units of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxic equivalency quotients (TEQ). The highest CALUX-TEQ values (>50 ng TEQ/kg dry wt) were found in sediments from the center of the Port of Rotterdam and from the North Sea canal near Amsterdam. The DR-CALUX activity of harbor sediments was classified by setting guideline values. None of the 257 harbor sediment samples investigated exceeded the maximum value of 1,000 ng TEQ/kg, while 94% of the samples fail the target value of 2 ng TEQ/kg. Threshold values (25 and 50 ng TEQ/kg) are intended as pass/fail criteria for offshore disposal of dredged material and were exceeded in 12 and 3% of the samples, respectively. DR-CALUX response did not always match with contamination of polychlorinated biphenyls (PCBs) as determined in bulk sediments (Σ7-PCB ranging from <1 to 456 μg/kg dry wt). Concentrations of planar PCBs, polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated-dibenzofuranes (PCDFs), polybrominated biphenyls (PBBs), and polybrominated-diphenylethers (PBDEs) were determined in 20 selected sediment extracts. On average, PCDD/Fs explained 50% of the DR-CALUX activity and planar PCBs 6%. Further research is needed to elucidate the unexplained part of the DR-CALUX response. The DR-CALUX is a highly sensitive and reproducible bioassay that can usefully complement standard PCB analysis, improving the hazard assessment of the disposal of dredged material in the North Sea
Metabolic Activation and Cytotoxicity of Labetalol Hydrochloride Mediated by Sulfotransferases
- …