3,258 research outputs found
Operation Moshtarak and the manufacture of credible, âheroicâ warfare
Richard Lance Keeble argues that Fleet Streetâs coverage of the Afghan conflict has served largely to promote the interests of the military/industrial/media complex â and marginalise the views of the public who have consistently appealed in polls for the troops to be brought back hom
Calcium supplements and cancer risk : a meta-analysis of randomised controlled trials
Peer reviewedPublisher PD
Effect of calcium supplements on risk of myocardial infarction and cardiovascular events : meta-analysis
Peer reviewedPublisher PD
Evolution and function of the epithelial cell-specific ER stress sensor IRE1ÎČ
Barrier epithelial cells lining the mucosal surfaces of the gastrointestinal and respiratory tracts interface directly with the environment. As such, these tissues are continuously challenged to maintain a healthy equilibrium between immunity and tolerance against environmental toxins, food components, and microbes. An extracellular mucus barrier, produced and secreted by the underlying epithelium plays a central role in this host defense response. Several dedicated molecules with a unique tissue-specific expression in mucosal epithelia govern mucosal homeostasis. Here, we review the biology of Inositol-requiring enzyme 1ÎČ (IRE1ÎČ), an ER-resident endonuclease and paralogue of the most evolutionarily conserved ER stress sensor IRE1α. IRE1ÎČ arose through gene duplication in early vertebrates and adopted functions unique from IRE1α which appear to underlie the basic development and physiology of mucosal tissues
STM induced hydrogen desorption via a hole resonance
We report STM-induced desorption of H from Si(100)-H(2) at negative
sample bias. The desorption rate exhibits a power-law dependence on current and
a maximum desorption rate at -7 V. The desorption is explained by vibrational
heating of H due to inelastic scattering of tunneling holes with the Si-H
5 hole resonance. The dependence of desorption rate on current and bias
is analyzed using a novel approach for calculating inelastic scattering, which
includes the effect of the electric field between tip and sample. We show that
the maximum desorption rate at -7 V is due to a maximum fraction of
inelastically scattered electrons at the onset of the field emission regime.Comment: 4 pages, 4 figures. To appear in Phys. Rev. Let
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