Multi-wavelength observations of afterglow of GRB 080319B and the modeling constraints

We present observations of the afterglow of GRB 080319B at optical, mm and radio frequencies from a few hours to 67 days after the burst. Present observations along with other published multi-wavelength data have been used to study the light-curves and spectral energy distributions of the burst afterglow. The nature of this brightest cosmic explosion has been explored based on the observed properties and it's comparison with the afterglow models. Our results show that the observed features of the afterglow fits equally good with the Inter Stellar Matter and the Stellar Wind density profiles of the circum-burst medium. In case of both density profiles, location of the maximum synchrotron frequency $\nu_m$ is below optical and the value of cooling break frequency $\nu_c$ is below $X-$rays, $\sim 10^{4}$s after the burst. Also, the derived value of the Lorentz factor at the time of naked eye brightness is $\sim 300$ with the corresponding blast wave size of $\sim 10^{18}$ cm. The numerical fit to the multi-wavelength afterglow data constraints the values of physical parameters and the emission mechanism of the burst.Comment: 8 Pages, 3 Figures, Accepted for publication to Astronomy and Astrophysics on 02/04/200

Religious Values, Practices and Pregnancy Outcomes: A Comparison of the Impact of Sect and Mainstream Christian Affiliation

In this report 6566 women enrolled in the Mater-University of Queensland Study of Pregnancy (MUSP) were separated into three groups; members of religious sects, Christians who attend church frequently and Christians who are infrequent attenders. These three groups, respectively labelled Christian sects, Christian attenders and lukewarm Christians were compared on a number of social background, lifestyle and pregnancy outcome variables. The sect members appeared to have the most favourable health, lifestyles and healthy babies at delivery, though this latter finding appears attributable to specific characteristics of the mother and her lifestyle. On most measures the children of lukewarm Christians appear to manifest the worst health while Christian attenders form a group whose children's health is between that of sect members and lukewarm Christians

Spontaneous development of Epstein-Barr Virus associated human lymphomas in a prostate cancer xenograft program

Prostate cancer research is hampered by the lack of in vivo preclinical models that accurately reflect patient tumour biology and the clinical heterogeneity of human prostate cancer. To overcome these limitations we propagated and characterised a new collection of patient-derived prostate cancer xenografts. Tumour fragments from 147 unsupervised, surgical prostate samples were implanted subcutaneously into immunodeficient Rag2-/-γC-/- mice within 24 hours of surgery. Histologic and molecular characterisation of xenografts was compared with patient characteristics, including androgen-deprivation therapy, and exome sequencing. Xenografts were established from 47 of 147 (32%) implanted primary prostate cancers. Only 14% passaged successfully resulting in 20 stable lines; derived from 20 independent patient samples. Surprisingly, only three of the 20 lines (15%) were confirmed as prostate cancer; one line comprised of mouse stroma, and 16 were verified as human donor-derived lymphoid neoplasms. PCR for Epstein-Barr Virus (EBV) nuclear antigen, together with exome sequencing revealed that the lymphomas were exclusively EBV-associated. Genomic analysis determined that 14 of the 16 EBV+ lines had unique monoclonal or oligoclonal immunoglobulin heavy chain gene rearrangements, confirming their B-cell origin. We conclude that the generation of xenografts from tumour fragments can commonly result in B-cell lymphoma from patients carrying latent EBV. We recommend routine screening, of primary outgrowths, for latent EBV to avoid this phenomenon

Community Inquiry Labs as Effective Community Informatics Tools

Meeting these challenges is crucial as we work to address community aspirations, capabilities, and problems. We are contributing to this effort through our current research and development on Community Inquiry Labs (CILs). A CIL is most importantly a concept, although we are developing webbased tools that are freely available to anyone wishing to support community inquiry online (http://inquiry.uiuc.edu/cil). Our ultimate aim is to empower communities by supporting the development of the next generation of creative ICT ideas, people, tools, and designs.unpublishedis peer reviewe

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Not AvailableBiological synthesis of nanoparticles has emerged as rapidly developing research area in nanotechnology across the globe with various biological entities being employed in production of nanoparticles constantly forming an impute alternative for conventional methods. Simple prokaryotes to complex eukaryotic organisms including higher plants are used for the fabrication of nanoparticles. Techniques such as Dynamic Light Scattering (DLS), Electron Microscopy (TEM, SEM), Atomic Force Microscopy (AFM), X-Ray Photoelectron Spectroscopy (XPS), Powder X-Ray Diffraction (XRD), Energy Dispersive X Ray Spectroscopy (EDS) and Fourier Transform Infrared Spectroscopy (FTIR) are used to elucidate the morphology, elemental composition and crystal structure of biosynthesized nanoparticles.Not Availabl

Letter to Editor - Cryptococcal Lymphadenitis Diagnosed by FNAC in a HIV Positive Individual

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Gear Up for the Action Replay: Leveraging Lensing for Enhanced Gravitational-wave Early Warning

Premerger gravitational-wave (GW) sky localization of binary neutron star (BNS) and neutron star–black hole (NSBH) coalescence events would enable telescopes to capture precursors and electromagnetic (EM) emissions around the time of the merger. We propose an astrophysical scenario that could provide early-warning times of hours to days before coalescence with subarcsecond localization, provided that these events are gravitationally lensed. The key idea is that if the BNS/NSBH is lensed, then so is the host galaxy identified via the EM counterpart. From the angular separation of the lensed host galaxy images, as well as its redshift and the (foreground) lens redshift, we demonstrate that, for galaxy-scale lenses, we can predict the time delays/arrival time differences assuming a standard lens model. We further assess the feasibility and benefits of lensing as a tool for early warning in various GW observing runs of the LIGO–Virgo–Kagra network, including Voyager and the third-generation network. To that end, we study the effect of the limited angular resolution of the telescopes on our ability to predict the time delays. We find that with an angular resolution of 0.05″ we can predict time delays of >1 day with 1 σ error bar of ${ \mathcal O }$ (hours) at best. We also construct realistic time delay distributions of detectable lensed BNSs/NSBHs to forecast the early-warning times we might expect in the observing scenarios we consider

Supporting Community Inquiry with Digital Resources

Today there are a number of fields that address the need to develop better means of employing information and communication technologies (ICTs) to help communities achieve their goals. Digital infrastructure and repositories are widely created to support the activities of educational, workplace, and scientific communities, as well as virtual communities of interest that may center on topics as diverse as entertainment, crisis management, and health. However, the research and development of ICTs faces numerous challenges. Community inquiry theory can help address some of these challenges. The Inquiry Page project supports a set of ICTs that have been developed by a community of inquiry in order to support communities of inquiry. The paper presents the theory of community inquiry and illustrates how inquiry theory can influence the research and development of ICTs and their adoption and use within real communities