743 research outputs found

    The Fermi edge singularity of spin polarized electrons

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    We study the absorption spectrum of a two-dimensional electron gas (2DEG) in a magnetic field. We find that that at low temperatures, when the 2DEG is spin polarized, the absorption spectra, which correspond to the creation of spin up or spin down electron, differ in magnitude, linewidth and filling factor dependence. We show that these differences can be explained as resulting from creation of a Mahan exciton in one case, and of a power law Fermi edge singularity in the other.Comment: 4 pages, 4 figures, published in Phys. Rev. Let

    Trial frequency effects in human temporal bisection : implications for theories of timing.

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    To contrast the classic version of the Scalar Expectancy Theory (SET) with the Behavioral Economic Model (BEM), we examined the effects of trial frequency on human temporal judgments. Mathematical analysis showed that, in a temporal bisection task, SET predicts that participants should show almost exclusive preference for the response associated with the most frequent duration, whereas BEM predicts that, even though participants will be biased, they will still display temporal control. Participants learned to emit one response (R[S]) after a 1.0-s stimulus and another (R[L]) after a 1.5-s stimulus. Then the effects of varying the frequencies of the 1.0-s and 1.5-s stimuli were assessed. Results were more consistent with BEM than with SET. Overall, this research illustrates how the impact of non-temporal factors on temporal discrimination may help us to contrast associative models such as BEM with cognitive models such as SET. Deciding between these two classes of models has important implications regarding the relations between associative learning and timing. This article is part of a Special Issue entitled: Associative and Temporal Learning.This research was supported by NIH grant MH033881. Jeremie Jozefowiez and Armando Machado acknowledge support from the Fundacao para a Ciencia e a Tecnologia as well as from the European project COST ISCH Action TD0904 "Time in Mental activity" (www.timely-cost.eu). We would like to thank Sean Gannon and Sarah Sterling for help running parts of the experiments, Mario Laborda, Bridget McConnell, Gonzalo Miguez, and James Witnauer for comments on an earlier version of this manuscript. Correspondence concerning this article should be addressed to Jeremie Jozefowiez, laboratoire URECA, Universite Lille Nord de France, Campus de Lille3, Domaine Universitaire du Pont de Bois, BP 60149, 58653 Villeneuve d'Ascq Cedex, France. jeremie.jozefowiez@univ-lille3fr

    Does Cataract Surgery Alleviate Poverty? Evidence from a Multi-Centre Intervention Study Conducted in Kenya, the Philippines and Bangladesh

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    BACKGROUND: Poverty and blindness are believed to be intimately linked, but empirical data supporting this purported relationship are sparse. The objective of this study is to assess whether there is a reduction in poverty after cataract surgery among visually impaired cases. METHODOLOGY/PRINCIPAL FINDINGS: A multi-centre intervention study was conducted in three countries (Kenya, Philippines, Bangladesh). Poverty data (household per capita expenditure--PCE, asset ownership and self-rated wealth) were collected from cases aged ≥50 years who were visually impaired due to cataract (visual acuity<6/24 in the better eye) and age-sex matched controls with normal vision. Cases were offered free/subsidised cataract surgery. Approximately one year later participants were re-interviewed about poverty. 466 cases and 436 controls were examined at both baseline and follow-up (Follow up rate: 78% for cases, 81% for controls), of which 263 cases had undergone cataract surgery ("operated cases"). At baseline, operated cases were poorer compared to controls in terms of PCE (Kenya: 22versus£35p=0.02,Bangladesh:22 versus £35 p = 0.02, Bangladesh: 16 vs 24p=0.004,Philippines:24 p = 0.004, Philippines: 24 vs 32 p = 0.0007), assets and self-rated wealth. By follow-up PCE had increased significantly among operated cases in each of the three settings to the level of controls (Kenya: 30versus£36p=0.49,Bangladesh:30 versus £36 p = 0.49, Bangladesh: 23 vs 23p=0.20,Philippines:23 p = 0.20, Philippines: 45 vs $36 p = 0.68). There were smaller increases in self-rated wealth and no changes in assets. Changes in PCE were apparent in different socio-demographic and ocular groups. The largest PCE increases were apparent among the cases that were poorest at baseline. CONCLUSIONS/SIGNIFICANCE: This study showed that cataract surgery can contribute to poverty alleviation, particularly among the most vulnerable members of society. This study highlights the need for increased provision of cataract surgery to poor people and shows that a focus on blindness may help to alleviate poverty and achieve the Millennium Development Goals

    Absorption in the fractional quantum Hall regime: trion dichroism and spin polarization

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    We present measurements of optical interband absorption in the fractional quantum Hall regime in a GaAs quantum well in the range 0 < nu < 1. We investigate the mechanism of singlet trion absorption, and show that its circular dichroism can be used as a probe of the spin polarization of the ground state of the two-dimensional electron system (2DES). We find that at nu = 1/3 the 2DES is fully spin-polarized. Increasing the filling factor results in a gradual depolarization, with a sharp minimum in the dichroism near nu = 2/3. We find that in the range 0.5 < nu < 0.85 the 2DES remains partially polarized for the broad range of magnetic fields from 2.75 to 11 Tesla. This is consistent with the presence of a mixture of polarized and depolarized regions.Comment: 4 pages, 4 figures (Fig 4 is in color

    Bio-Inspired Load Balancing In Large-Scale WSNs Using Pheromone Signalling

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    Wireless sensor networks (WSNs) consist of multiple, distributed nodes each with limited resources. With their strict resource constraints and application-specific characteristics, WSNs contain many challenging tradeoffs. This paper proposes a bioinspired load balancing approach, based on pheromone signalling mechanisms, to solve the tradeoff between service availability and energy consumption. We explore the performance consequences of the pheromone-based load balancing approach using (1) a system-level simulator, (2) deployment of real sensor testbeds to provide a competitive analysis of these evaluation methodologies. The effectiveness of the proposed algorithm is evaluated with different scenario parameters and the required performance evaluation techniques are investigated on case studies based on sound sensors

    Vaccination of Rhesus Macaques with a Recombinant Measles Virus Expressing Interleukin-12 Alters Humoral and Cellular Immune Responses

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    Lack of a vaccine for infants and immunosuppression after infection are problems associated with measles virus (MV). Because interleukin (IL)-12 has been used successfully as a vaccine adjuvant and because inhibition of IL-12 expression has been associated with immunosuppression during measles, the addition of IL-12 may enhance the immune response to MV. To determine the effect of IL-12 supplementation, rhesus macaques were vaccinated with a recombinant MV expressing IL-12; these macaques had increased interferon-γ production by CD4+ T cells, decreased production of IL-4, and lower levels of MV-specific immunoglobulin G4 and neutralizing antibody. Lymphoproliferative responses to mitogen were not improved. IL-12 supplementation altered the T helper type 2 bias of the immune response after MV vaccination, had a detrimental effect on the protective neutralizing antibody response, and did not improve other manifestations of immunosuppression. Reduced IL-12 levels are not the sole factor in MV-induced immunosuppressio

    Challenges of assessing community mortality due to respiratory viruses in children aged less than 5 years

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    Background: Estimating the real impact of respiratory syncytial virus (RSV) disease is key for the development of vaccines and treatments. Ascertaining the burden of community mortality due to RSV is challenging due to the lack of primary data. Therefore, conducting observational studies to determine the factors associated with community mortality due to the virus in developing countries is important.Objective: Our aim in this study was to describe the obstacles, gaps, and challenges that investigators face in low-income, vulnerable regions in 4 developing countries on 3 continents.Results: The main obstacles and challenges of ascertaining community mortality due to RSV were defining strategies to consent families for testing before burial, sampling individuals at the household level, supporting bereaved parents with different cultural and religious backgrounds, establishing tailored strategies for studies in challenging settings, and integrating RSV mortality data from nasopharyngeal samples.Conclusion: Detailed logistical planning based on population sociodemographic information, grief counseling, staff training, and a multidisciplinary approach with adequate laboratory infrastructure is critical to successful observational community-based RSV studies
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