The economic impact of sanctions on the Russian economy

This paper assesses the impact of the EU and NATO sanctions on the Russian economy. An examination of the data revealed that the sanctions have directly impacted on various sectors of the Russian economy. Notable among them were the financial sector which includes the banks, major publicly owned companies in the fuel/energy sector as well as the military and technological equipment. These sanctions severely constrained these sectors as they struggled with lack of funding and investment. The economy also witnessed huge capital flight or outflow at an estimated value of $7.8bn, which was further compounded by gross negative capital inflow in the form of FDI’s (foreign direct investments). In addition to that, the embargo on food imports as well as trade sanctions led to a rise in inflation which further resulted to a rise in commodity prices and by extension loss of confidence in the falling Ruble. The sanctions also led to erratic trade flows and loss of market share. On the contrary, despite the sanctions the Russian economy moved to 45th place in the global competitiveness report. Besides the Russian government continuously offer support to its financial institutions in the form of low interest loans which led to their buoyancy

Political stability and innovation in Africa

This paper examines the role of institutional factors, primarily, political stability, in shaping the dynamics of innovation activity in today’s modern society. Using panel data consisting of 26 African countries from the period between 1996 and 2016 as well as employing the negative binomial estimate, we model the impact of those factors on the number of applications for patents per resident. GDP per capita, education and also other institutional factors including the rule of law and financial freedom. The results reveal a strong positive effect of the rule of law on patenting activity. © Foundation of International Studies, 2020 © CSR, 2020.Deutscher Akademischer Austauschdienst, DAADMinistry of Education and Science of the Russian Federation, MinobrnaukaMinisterstwo Nauki i Szkolnictwa Wyższego, MNiSWThe authors are thankful to the Russian Ministry of Education and Science, DAAD, The Ministry of Science and Higher Education in Poland for financial support to carry out this research. Thanks (IOS, Regensburg) for hosting James Okrah for the period of his research internship with them, with special thanks to Dr Alexander Nepp (Supervisor), Dr. Olga Popova (IOS, Regensburg), Prof. Richard Frensch (IOS, Regensburg) and Dr Stefan Huber for their support

Оценка влияния конкуренции фирм на инновации в России

Инновации - важный фактор выживания компании в конкурентном мире бизнеса. Фирмы, действующие как на свободных, так и на конкурентных рынках, вынуждены внедрять более эффективные методы производства, чтобы предоставить потребителям новые улуч山енные продукты. В данной статье рассматривается влияние конкуренции на инновации на свободных и конкурентных рынках, исходя из цели российского правительства увеличить производительность малых и средних предприятий до 32% ВВП. Для анализа данных исследования предприятий Всемирного банка была применена логит-модель. Полученные выводы свидетельствуют о существенном негативном влиянии жесткой конкуренции на инновации. В частности, конкуренция отрицательно влияет на такие показатели, как инновации в продуктах, процессах и новых продуктах, приводя к их снижению на 5%, 3% и 3,5% соответственно. Модель пошаговых инноваций показывает, что конкуренция стимулирует инновации в фирмах на состязательных рынках. Кроме того, более высокий уровень конкуренции негативно влияет на создание новых инновационных продуктов. Согласно результатам анализа, острая конкуренция может снижать способность фирм к инновациям, особенно в области разработки продуктов, улучшения процессов и внедрения новых продуктов. Однако выступая в качестве движущей силы, конкуренция заставляет компании вводить нов山ества, чтобы поддерживать свою конкурентоспособность на рынке. Следовательно, усиление конкуренции может привести к отвлечению ресурсов организаций на исследования и разработки (НИОКР), потенциально ограничивая возможность внедрения новых продуктов.Innovation is an essential component of a company’s survival in this competitive world of business. Firms in free and competitive marketplaces are compelled to adopt more efficient production techniques and provide customers with new and improved products. This research examines the impact of competition on innovation in free and competitive marketplaces.The study is motivated by the Russian government’s goal of increasing productivity of small and medium-sixed enterprises (SMEs) to 32% of gross domestic product. The study employed the Logit model to analyse the data from the World Bank Enterprise Survey.The findings reveal that fierce competition has a significant negative effect on innovation. Specifically, competition reduces product, process, and new product innovation by 5%, 3%, and 3.5% respectively.The step-by-step innovation model indicates that competition stimulates innovation in firms operating in contestable markets. Additionally, higher levels of competition negatively affect new product innovation. These results suggest that intense competition may impede firms’ ability to innovate, particularly in the areas of product development, process improvement, and introducing new products. However, competition acts as a driving force that compels firms to innovate in order to maintain their competitiveness in the market. Consequently, increased competition may lead to a diversion of resources towards research and development (R&D), potentially limiting firms’ capacity to introduce new products.Автор выражает глубокую признательность Екатерине Цыганковой за поддержку и оказанную помощь в проведении исследования, её бесценный опыт и знания в области российского права. Также автор выражает искреннюю благодарность анонимным рецензентам и редактору за их вклад, ценные замечания и предложения, повлиявшие на качество статьи. Их преданность делу и стремление к совершенству достойны похвалы.I would like to express my deepest gratitude to Ekaterina Tsygankova for her unwavering support and invaluable expertise in Russian law. Her immense knowledge has been instrumental in shaping and refining this work. I would also like to extend my sincere thanks to the anonymous reviewers and the editor for their contributions. Their insightful comments and suggestions have played a crucial role in the development and improvement of this script. Their dedication and commitment to excellence are truly commendable

The expression of SLAMF7 levels in malignant B cells: a novel therapeutic pathway for patients with CLL

Signalling lymphocyte activation molecule (SLAM) F7 is found on the surface of some immune cells including B-lymphocytes. Its activation leads to the proliferation or differentiation of immune cells. The objectives of the study were to measure SLAMF7 expression levels on B-CLL cells, and to upregulate the expression of SLAMF7 with phorbol myristate acetate (PMA) and Bryostatin. The levels of expression of SLAMF7 receptors of B-CLL cells from patients were measured; using immunofluorescence, flow cytometry, confocal microscopy and reverse transcriptase polymerase chain reaction (RT-PCR). The effects of treatments with PMA and Bryostatin were determined from different patients. Different levels of SLAMF7 expression were found to be associated with B-CLL cells from different patients. PMA treatment of B-CLL cells showed more positive SLAMF7 staining with the majority of the extracted B-CLL cell cases, while less positive results were associated with Bryostatin treatment. The study has shown that both PMA and Bryostatin could upregulate SLAMF7. Successful modulation of SLAMF7 expression may provide a novel target for the treatment of patients with CLL.Keywords: SLAMF7, RT PCR, Elotuzumab, Bryostatin, PM

Trends in Weekly Reported Net use by Children During and after Rainy Season in Central Tanzania.

The use of long-lasting insecticidal nets (LLINs) is one of the principal interventions to prevent malaria in young children, reducing episodes of malaria by 50% and child deaths by one fifth. Prioritizing young children for net use is important to achieve mortality reductions, particularly during transmission seasons. Households were followed up weekly from January through June 2009 to track net use among children under seven under as well as caretakers. Net use rates for children and caretakers in net-owning households were calculated by dividing the number of person-weeks of net use by the number of person-weeks of follow-up. Use was stratified by age of the child or caretaker status. Determinants of ownership and of use were assessed using multivariate models. Overall, 60.1% of the households reported owning a bed net at least once during the study period. Among net owners, use rates remained high during and after the rainy season. Rates of use per person-week decreased as the age of the child rose from 0 to six years old; at ages 0-23 months and 24-35 months use rates per person-week were 0.93 and 0.92 respectively during the study period, while for children ages 3 and 4 use rates per person-week were 0.86 and 0.80. For children ages 5-6 person-week ratios dropped to 0.55. This represents an incidence rate ratio of 1.67 for children ages 0-23 months compared to children aged 5-6. Caretakers had use rates similar to those of children age 0-35 months. Having fewer children under age seven in the household also appeared to positively impact net use rates for individual children. In this area of Tanzania, net use is very high among net-owning households, with no variability either at the beginning or end of the rainy season high transmission period. The youngest children are prioritized for sleeping under the net and caretakers also have high rates of use. Given the high use rates, increasing the number of nets available in the household is likely to boost use rates by older children

Efficacious, effective, and embedded interventions: Implementation research in infectious disease control

Background: Research in infectious disease control is heavily skewed towards high end technology; development of new drugs, vaccines and clinical interventions. Oft ignored, is the evidence to inform the best strategies that ensure the embedding of interventions into health systems and amongst populations. In this paper we undertake an analysis of the challenge in the development of research for the sustainable implementation of disease control interventions. Results: We highlight the fundamental differences between the research paradigms associated with the development of technologies and interventions for disease control on the one hand and the research paradigms required for enhancing the sustainable uptake of those very same interventions within the communities on the other. We provide a definition for implementation research in an attempt to underscore its critical role and explore the multidisciplinary science needed to address the challenges in disease control. Conclusion: The greatest value for money in health research lies in the sustainable and effective implementation of already proven, efficacious solutions. The development of implementation research that can help provide some solutions on how this can be achieved is sorely needed

Malaria and anemia prevention in pregnant women of rural Burkina Faso

BACKGROUND: Pregnant women are a major risk group for malaria in endemic areas. Only little information exists on the compliance of pregnant women with malaria and anaemia preventive drug regimens in the rural areas of sub-Saharan Africa (SSA). In this study, we collected information on malaria and anaemia prevention behaviour in pregnant women of rural Burkina Faso. METHODS: Cross-sectional qualitative and quantitative survey among 225 women of eight villages in rural northwestern Burkina Faso. Four of the villages had a health centre offering antenatal care (ANC) services while the other four were more than five kilometers away from a health centre. RESULTS: Overall ANC coverage (at least one visit) was 71% (95% in health centre villages vs 50% in remote villages). Malaria and anaemia were considered as the biggest problems during pregnancy in this community. ANC using women were quite satisfied with the quality of services, and compliance with malaria and anaemia prevention regimens (chloroquine and iron/folic acid) was high in this population. Knowledge on the benefit of bed nets and good nutrition was less prominent. Distance, lack of money and ignorance were the main reasons for women to not attend ANC services. CONCLUSIONS: There is an urgent need to improve access of rural SSA women to ANC services, either through increasing the number of rural health centres or establishing functioning outreach services. Moreover, alternative malaria and anaemia prevention programmes such as intermittent preventive treatment with effective antimalarials and the distribution of insecticide-treated bed nets need to become implemented on a large scale

Determinants of bed net use in children under five and household bed net ownership on Bioko Island, Equatorial Guinea

BACKGROUND: As part of comprehensive malaria control strategies, the Bioko Island Malaria Control Project (BIMCP) distributed 110,000 long-lasting insecticide-treated nets (LLIN) in late 2007 with the aim of providing one net for each sleeping area. Despite attaining initially very high levels of net coverage and net use, many children under five years of age did not sleep under a net by 2009, according to annual malaria indicator surveys. The aim of this study was to assess the determinants of bed net use in children under five and bed net ownership of the households in which they live. METHODS: Using data from annual cross-sectional household surveys of 2008 and 2009, we investigated factors associated with sleeping under a mosquito net the night prior to the survey, and a households owning at least one net, in all households which had at least one child under five years. Amongst others, caregiver's knowledge of malaria and household characteristics including a socio-economic score (SES), based on ownership of household assets, were analysed for their effect on net ownership and use. RESULTS: There was a decline of around 32% in the proportion of households that owned at least one net between 2008 and 2009. Higher household bed net ownership was associated with knowing how malaria was prevented and transmitted, having the house sprayed in the previous 12 months, having fewer children under five in the household, and children being sick at some point in the previous 14 days. Higher bed net use in children < 5 was associated with being sick at some point in the last 14 days prior to the survey, living in an urban area, more years of education of the head of the household, household ownership of at least one ITN (as opposed to an untreated net) and the year in which the survey took place. CONCLUSIONS: The big fall in bed net use from 2008 to 2009 was attributable to the striking decline in ownership. Although ownership was similar in rural and urban areas, rural households were less likely to protect their children with bed nets. Knowledge about malaria was an important determinant of bed net ownership. Further research is needed to elucidate the decline in bed net ownership between 2008 and 2009

Bed net use and associated factors in a rice farming community in Central Kenya

<p>Abstract</p> <p>Background</p> <p>Use of insecticide-treated nets (ITNs) continues to offer potential strategy for malaria prevention in endemic areas. However their effectiveness, sustainability and massive scale up remain a factor of socio-economic and cultural variables of the local community which are indispensable during design and implementation stages.</p> <p>Methods</p> <p>An ethnographic household survey was conducted in four study villages which were purposefully selected to represent socio-economic and geographical diversity. In total, 400 households were randomly selected from the four study villages. Quantitative and qualitative information of the respondents were collected by use of semi-structured questionnaires and focus group discussions.</p> <p>Results</p> <p>Malaria was reported the most frequently occurring disease in the area (93%) and its aetiology was attributed to other non-biomedical causes like stagnant water (16%), and long rains (13%). Factors which significantly caused variation in bed net use were occupant relationship to household head (χ²= 105.705; df 14; P = 0.000), Age (χ²= 74.483; df 14; P = 0.000), village (χ²= 150.325; df 6; P = 0.000), occupation (χ²= 7.955; df 3; P = 0.047), gender (χ²= 4.254; df 1; P = 0.039) and education levels of the household head or spouse (χ²= 33.622; df 6; P = 0.000). The same variables determined access and conditions of bed nets at household level. Protection against mosquito bite (95%) was the main reason cited for using bed nets in most households while protection against malaria came second (54%). Colour, shape and affordability were some of the key potential factors which determined choice, use and acceptance of bed nets in the study area.</p> <p>Conclusion</p> <p>The study highlights potential social and economic variables important for effective and sustainable implementation of bed nets-related programmes in Sub-Saharan Africa.</p