Farmakologie*

As farmakoloog verbonde aan hierdie Universiteit sien ek my taak as tweeledig — eerstens om ’n bydrae te lewer tot die vorming van studente en behulpsaam te wees met die vergaring van kennis wat hulle later as aptekers nodig sal kry, en tweedens om te werk aan die uitbouing en voortgang van die wetenskap farmakologie. Dit is duidelik dat dit nie my bedoeling kan wees om voor so ’n gedifferensieerde gehoor soos u ’n sterk gespesialiseerde wetenskaplike betoog te hou nie. Vir vele van u is dit seker die eerste en enigste lesing wat u ooit sal hoor betreffende hierdie vertakking van die wetenskap. Daarom sal ek liefs ’n voordrag hou nie in nie, maar oor die farmakologie

A comparison of the effects of no radrenaline, adrenaline and some phenylephrine derivatives on alpha-, betal " and beta2- adrenergic receptors

The possibility of two types of beta-adrenergic receptors is supported by the results presented. It is shown that the phenylephrine group of compounds have more pronounced affinities towards the beta,-(cardiac) adrenergic receptors than towards the beta,-(bronchial) adrenergic receptors. The cardioselective action is the greatest in the case of ethylnorphenylephrine. It is postulated that the presence of a small substituent on the amino nitrogen and a (only one) meta-hydroxyl group may contribute towards cardioselectivity in the case of phenylethylam;ne derivatives. Ethylnorphenylephrine has a relatively low affinity towards the alpha-adrenergic receptors

Tricyclic antidepressives - A possible mode of action

No Abstract

Serotonin and its derivatives: a study on structure-activity relations

Contains fulltext : mmubn000001_221446338.pdf (publisher's version ) (Open Access)Promotor : E. Ariëns136 p