SAT: A Software for Assessing the Risk of Desertification in Spain

Desertification is a major global environmental issue exacerbated by climate change. Strategies to combat desertification include prevention which seeks to reverse the process before the system reaches the stable desertified state. One of these initiatives is to implement early warning tools. This paper presents SAT (the Spanish acronym for Early Warning System), a decision support system (DSS), for assessing the risk of desertification in Spain, where 20% of the land has already been desertified and 1% is in active degradation. SAT relies on three versions of a Generic Desertification Model (GDM) that integrates economics and ecology under the predator-prey paradigm. The models have been programmed using Vensim, a type of software used to build and simulate System Dynamics (SD) models. Through Visual Basic programming, these models are operated from the Excel environment. In addition to the basic simulation exercises, specially designed tools have been coupled to assess the risk of desertification and determine the ranking of the most influential factors of the process. The users targeted by SAT are government land-use planners as well as desertification experts. SAT tool is implemented for five case studies, each one of them representing a desertification syndrome identified in Spain. Given the general nature of the tool and the fact that all United Nations Convention to Combat Desertification (UNCCD) signatory countries are committed to developing their National Plans to Combat Desertification (NPCD), SAT could be exported to regions threatened by desertification and expanded to cover more case studies.This work was funded by TRAGSATEC Public Enterprise on behalf of the Spanish Ministry of Agriculture, Food, and Environment under Contract 23.674. The generic desertification model was developed under the umbrella of DeSurvey IP (European Commission FP6 Contract no. 003950). The paper was written within the framework of the project BIODESERT, funded by the European Research Council (ERC Grant agreement no. 647038)

AQUACOAST: A Simulation Tool to Explore Coastal Groundwater and Irrigation Farming Interactions

In the framework of coastal groundwater-dependent irrigation agriculture, modelling becomes indispensable to know how this renewable resource responds to complex (usually not conceptualized nor monitored) biophysical, social, and economic interactions. Friendly user interfaces are essential to involve nonmodeling experts in exploiting and improving models. Decision support systems (DSS) are software systems that integrate models, databases, or other decision aids and package them in a way that decision makers can use. This paper addresses these two issues: firstly with the implementation of a System Dynamics (SD) model in Vensim software that considers the integration of hydrological, agronomic, and economic drivers and secondly with the design of a Venapp, push-button interfaces that allow users access to a Vensim model without going through the Vensim modelling environment. The prototype designed, the AQUACOAST tool, gives an idea of the possibilities of this type of models to identify and analyze the impact of apparently unrelated factors such as the prices of cultivated products, subsidies or exploitation costs on the advance of saltwater intrusion, and the great threat to coastal groundwater-dependent irrigation agriculture systems.This study was funded by the European Research Council grant agreement no. 647038 (BIODESERT)

The Importance of Prevention in Tackling Desertification: An Approach to Anticipate Risks of Degradation in Coastal Aquifers

Groundwater degradation is a major issue on an increasingly hot and thirsty planet. The problem is critical in drylands, where recharge rates are low and groundwater is the only reliable resource in a context of water scarcity and stress. Aquifer depletion and contamination is a process of desertification. Land Degradation Neutrality is regarded as the main initiative to tackle land degradation and desertification. It is embedded in target 15.3 of the Sustainable Development Goals and focused on preventing these dynamics. Within this framework, we present an approach to assess risks of degradation and desertification in coastal basins with aquifers threatened by seawater intrusion. The approach utilizes an integrated system dynamics model representing the main relationships between the aquifer and an intensively irrigated area (greenhouses) driven by short- and medium-term profitability. The study area is located in a semi-arid region in Southern Spain, the Gualchos stream basin, which contains the Castell de Ferro aquifer. We found that the risk of salinization of the aquifer is 73%, while there is a 70% risk that the system would increases its demand for surface water in the future, and the chance of doubling the current demand is almost 50%. If the current system of reservoirs in the area were not able to satisfy such an increase in demand because of climate change, the basin would be at a serious risk of desertification.This research was funded by the European Research Council (ERC grant agreement 647038 (BIODESERT)) and by the project 101086497 funded by European Union’s Horizon-CL6-2022-Governance-01-07 research and innovation program

Scientific Programming Tools for Water Management

This special issue delivers a platform in which researchers expose intersections between algorithm design, software platforms, and hardware architectures to deal with emerging challenges in the scientific field of management of water and water-dependent resources. Since the call for papers was announced in June 2019, this special issue has received 10 manuscripts. After a rigorous review process, 6 papers have been finally accepted for publication. Published papers deal with groundwater quality monitoring, coastal groundwater-dependent irrigation agriculture, desertification risk, water recovery from tailings, future scenarios of water resources, and vulnerability of coastal aquifers

Assessing the sensitivity of a Mediterranean commercial rangeland to droughts under climate change scenarios by means of a multidisciplinary integrated model

Rangeland productivity is strongly conditioned by the amount and temporal distribution of precipitation. Thus, the worsening of droughts with climate change could be a serious threat to their existence. This paper presents a modelling study aimed at evaluating the sensitivity of a valuable type of commercial rangelands, namely Spanish dehesas, to increases in the frequency and intensity of droughts driven by climate change. The assessment consisted in a multi-way ANOVA carried out on the basis of 5400 simulations of a multidisciplinary integrated model. It included two blocking factors linked to climate change scenarios, namely Representative Concentration Pathway and downscaling method, and two treatment factors, namely return period and severity of droughts. The levels of all factors were included as part of the simulation scenarios. The response variables constituted a summary of model's behaviour throughout one simulation. They were average profits per farmer and average stocking rate, both calculated over the entire simulation period, and remaining soil depth at the end of the simulation. The effects of the treatment factors on the response variables were small for all blocks, thereby suggesting that the sensitivity, and thus the vulnerability, of Spanish dehesas to the worsening of droughts would be low under climate change. Farmers were defined as conservative in all model simulations, that is, they minimized changes in the size of their herds and bought supplementary feed to meet shortfalls in livestock feed unless it was excessively expensive. Thus, we conclude that this group strategy could explain the adaptive capacity of Spanish dehesas to droughts. This paper shows that multidisciplinary integrated models are valuable learning tools to acquire insights into the relationships between climate, ecologic and socio-economic factors. Although there is a recurrent call for holistic studies, they are still rare in the rangeland literature. Hopefully, this paper will motivate some researchers to consider this approach.This paper was written within the framework of Junta de Andalucía Research Project ‘Mesotopos: Habitat Conservation and Land Degradation in Andalucía’ P08 RNM-4023. The partial support of the Chilean FONDECYT Research Project 1161105 is also acknowledged. The authors are funded by the European Research Council grant agreement n◦ 647038 (BIODESERT)

Characterization of modular deposits for urban drainage networks using CFD techniques

[EN] The growing urban development of population centers in much of the world joined with the significant effects of climate change are causing an increasingly important and recurring increase of the damage caused by flooding. Much of the drainage networks of cities were designed for precipitation characteristics and return periods that have proved to be insufficient with the lapse of time. Therefore, solutions need to be addressed both to reduce runoff generated flows as to control circulating ones through the rainwater drainage networks. All these flow control rain technologies are commonly known as SUDS (Sustainable Urban Drainage), term that encompasses a multitude of solutions to control runoff although many of them require significant costs that make them practically unviable. Therefore, not only should focus on reducing runoff input to the network but also in the flow control techniques development. The idea is to design strategies to reduce flow rain peaks and maximize the capacity of existing networks. The use of detention and storm tanks for flood control is a solution increasingly used as an alternative one to control increased rainfall caused by climate change [1]. Nature and execution of storm tanks can be very diverse, from conventional way based on concrete structures to the most innovative ones in which modular structures are employed to improve the construction speed if many modular units are required at the same time that minimizing urban supply disruption is achieved. Currently, a wide range of modular structures exists on the market with both, different geometries and sizes. In this study the Aquacell brand supplied by Mexichem-PAVCO in Colombia shown in Fig. 1 has been chosen for the development of this study.S849218

Outcomes of off-label drug uses in hospitals: a multicentric prospective study

Purpose: The study aims to assess the clinical evidence, outcome and cost of off-label use of medicines in the hospital setting. Methods: A multicentric prospective cohort study of patients treated with off-label medicines was carried out in five tertiary hospitals from May 2011 to May 2012. Information on clinical characteristics of patients, drugs, outcomes and costs was collected. Patients were followed up to 6 months, and information was assessed by reviewing clinical records and interviewing physicians. Results: A total of 226 patients were included. The median (interquartile range (IQR)) age of patients was 46 (3362) years; 59 % were women. Patients had received a median of three previous treatments, and a lack of response (or suboptimal) was the main reason for off-label use (72.1 %). A total of 232 off-label medicines were administered for 102 different indications. The most frequent medicines were rituximab (49; 21.1 %), botulinum toxin (25; 10.7 %) and omalizumab (14; 6.0 %). In 117 (51.8 %) cases, the level of clinical evidence for their use was low. A partial clinical response was observed in 82 patients (36.3 %), complete response in 71 (31.4 %) and stabilization in 11 (4.9 %). A total of 58 (26.5 %) patients had adverse effects, which in 11 (4.9 %) were severe. The median (IQR) cost per patient was 2,943.07 (541.95,872.54). Conclusions: There was a high variability of off-label medicines and indications. Although the clinical evidence of off-label medicines was often low, clinical response was observed in many patients with previous multiple treatment failure, but at the expense of some adverse effects and a high cost. Registers of patients would be helpful for clinical decisions, although clinical trials are needed

Outcomes of off-label drug uses in hospitals : a multicentric prospective study

Altres ajuts: We would to thank the Spanish Ministry of Health, Social Affairs and Equality for their financial support given though a grant from the scholarship EC-206 in the public call for the promotion of independent clinical research (SAS/2370/2010 order of September 27)The study aims to assess the clinical evidence, outcome and cost of off-label use of medicines in the hospital setting. A multicentric prospective cohort study of patients treated with off-label medicines was carried out in five tertiary hospitals from May 2011 to May 2012. Information on clinical characteristics of patients, drugs, outcomes and costs was collected. Patients were followed up to 6 months, and information was assessed by reviewing clinical records and interviewing physicians. A total of 226 patients were included. The median (interquartile range (IQR)) age of patients was 46 (33-62) years; 59 % were women. Patients had received a median of three previous treatments, and a lack of response (or suboptimal) was the main reason for off-label use (72.1 %). A total of 232 off-label medicines were administered for 102 different indications. The most frequent medicines were rituximab (49; 21.1 %), botulinum toxin (25; 10.7 %) and omalizumab (14; 6.0 %). In 117 (51.8 %) cases, the level of clinical evidence for their use was low. A partial clinical response was observed in 82 patients (36.3 %), complete response in 71 (31.4 %) and stabilization in 11 (4.9 %). A total of 58 (26.5 %) patients had adverse effects, which in 11 (4.9 %) were severe. The median (IQR) cost per patient was €2,943.07 (541.9-5,872.54). There was a high variability of off-label medicines and indications. Although the clinical evidence of off-label medicines was often low, clinical response was observed in many patients with previous multiple treatment failure, but at the expense of some adverse effects and a high cost. Registers of patients would be helpful for clinical decisions, although clinical trials are needed. The online version of this article (doi:10.1007/s00228-014-1746-2) contains supplementary material, which is available to authorized users

Hypospadias: a review

Hypospadias is a congenital malformation of the male external genitalia, which includes: anomalous location proximal to the urethral meatus, in any portion of the glans penis and perineum, hooded dorsal foreskin, and inverted penile curvature on the dorsal side of the foreskin. The etiology has been considered multifactorial, secondary to the interaction of environmental factors with specific genetic background. It represents the second most frequent congenital defect in male newborns. It has increasing prevalence rates of 0.25 new cases per 10,000 newborns per year. Risk factors that have been identified include infants small for gestational age with weight below the 10th percentile, head length and/or circumference, intrauterine growth restriction, and placental insufficiency. Regarding environmental risk factors, maternal exposure to pesticides has been linked. Prenatal diagnosis has been described, however proximal hypospadias is usually detected, making it difficult to diagnose distal hypospadias using this method. So usually the diagnosis is made after birth during the physical examination. To date, more than 300 surgical techniques are known for the correction of hypospadias. The treatment of distal hypospadias is currently performed in one time; the management of proximal hypospadias is controversial; one group favors the one-stage procedure, while other groups choose to perform the two-stage procedure

Staghorn renal stones: a review

Staghorn lithiasis is described as the presence of stones in the urinary tract that create a mold of the renal collecting system, with the characteristic of being branched. It has a strong association with urinary tract infections caused by urea-splitting organisms. The composition of the stone usually consists of pure magnesium ammonium phosphate (struvite), or a mixture of struvite and calcium carbonate apatite. It is classified as complete and partial. In the complete one, the stones occupy the renal pelvis and the calyceal system, or more than 80% of the collecting system; unlike the partial ones that occupy the renal pelvis and at least two calyces. Computed tomography without intravenous contrast is the imaging method of choice for diagnosis and planning of surgical intervention. Allowing an accurate assessment of the morphology and location of the stones; that will set the standard for guiding percutaneous access. Complete stone cleaning is the cornerstone of staghorn lithiasis treatment. The guidelines of the European Association of Urology and the American Association of Urology mention that percutaneous nephrolithotomy continues to be the treatment of choice for large stones. Conservative management is related to renal loss and urosepsis, reporting a mortality of 28 % up to 30% within 10 years, as well as a 36% risk of developing chronic kidney disease