481 research outputs found

    Tapered optical fibers as tools for probing magneto-optical trap characteristics

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    We present a novel technique for measuring the characteristics of a magneto-optical trap for cold atoms by monitoring the spontaneous emission from trapped atoms coupled into the guided mode of a tapered optical nanofiber. We show that the nanofiber is highly sensitive to very small numbers of atoms close to its surface. The size and shape of the MOT, determined by translating the cold atom cloud across the tapered fiber, is in excellent agreement with measurements obtained using the conventional method of fluorescence imaging using a CCD camera. The coupling of atomic fluorescence into the tapered fiber also allows us to monitor the loading and lifetime of the trap. The results are compared to those achieved by focusing the MOT fluorescence onto a photodiode and it was seen that the tapered fiber gives slightly longer loading and lifetime measurements due to the sensitivity of the fiber, even when very few atoms are present.Comment: 21 pages, 5 figure

    Third Space: When Learning Matters -- School Profiles & Demographics

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    Third Space tells the riveting story of the profound changes in the lives of kids, teachers, and parents in ten economically disadvantaged communities across the country that place their bets on the arts as a way to create great schools. The schools become caring communities where kids - many of whom face challenges of poverty, the need to learn English, and to surmount learning difficulties - thrive and succeed and where teachers find new joy and satisfaction in teaching.This document is the profiles and demographics of the schools being studied

    Binding of DNA by a dinitro-diester calix[4]arene: denaturation and condensation of DNA

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    A study of a dinitro-diester calix[4]arene (5,17-(3-nitrobenzylideneamino)-11,23-di-tert-butyl- 25,27-diethoxycarbonyl methyleneoxy-26,28-dihydroxycalix[4]arene) interaction with calf-thymus DNA was carried out using several techniques. The measurements were done at various molar ratios X=[calixarene]/[DNA]. Results show diverse changes in the DNA conformation depending on the X value. Thus, at low macrocycle concentration, the calixarene binds to the polynucleotide. This interaction, mainly in groove mode, weakens the hydrogen bonds between the base pairs of the helix inducing the denaturation of the double strands, as well as the condensation of the macromolecule, from an extended coil state to a globular state. An opposite effect is observed at X molar ratios higher than 0.07. The de-condensation of DNA happens, that is, the transition from a compact state to a more extended conformation, probably due to the stacking of calixarene molecules in the solution. Results also show the importance of making a proper choice of the system under consideration

    High-frequency monitoring of nitrogen and phosphorus response in three rural catchments to the end of the 2011–2012 drought in England

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    This paper uses high-frequency bankside measurements from three catchments selected as part of the UK government-funded Demonstration Test Catchments (DTC) project. We compare the hydrological and hydrochemical patterns during the water year 2011–2012 from the Wylye tributary of the River Avon with mixed land use, the Blackwater tributary of the River Wensum with arable land use and the Newby Beck tributary of the River Eden with grassland land use. The beginning of the hydrological year was unusually dry and all three catchments were in states of drought. A sudden change to a wet summer occurred in April 2012 when a heavy rainfall event affected all three catchments. The year-long time series and the individual storm responses captured by in situ nutrient measurements of nitrate and phosphorus (total phosphorus and total reactive phosphorus) concentrations at each site reveal different pollutant sources and pathways operating in each catchment. Large storm-induced nutrient transfers of nitrogen and or phosphorus to each stream were recorded at all three sites during the late April rainfall event. Hysteresis loops suggested transport-limited delivery of nitrate in the Blackwater and of total phosphorus in the Wylye and Newby Beck, which was thought to be exacerbated by the dry antecedent conditions prior to the storm. The high rate of nutrient transport in each system highlights the scale of the challenges faced by environmental managers when designing mitigation measures to reduce the flux of nutrients to rivers from diffuse agricultural sources. It also highlights the scale of the challenge in adapting to future extreme weather events under a changing climate

    Stochastic Norton-Simon-Massagu\ue9 Tumor Growth Modeling: Controlled and Mixed-Effects Uncontrolled Analysis

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    Tumorigenesis is a complex process that is heterogeneous and affected by numerous sources of variability. This study presents a stochastic extension of a biologically grounded tumor growth model, referred to as the Norton-Simon-Massagu\ue9 (NSM) tumor growth model. We first study the uncontrolled version of the model where the effect of chemotherapeutic drug agent is absent. Conditions on the model\u2019s parameters are derived to guarantee the positivity of the tumor volume and hence the validity of the proposed stochastic NSM model. To calibrate the proposed model we utilize a maximum likelihood- based estimation algorithm and population mixed-effect modeling formulation. The algorithm is tested by fitting previously published tumor volume mice data. Then, we study the controlled version of the model which includes the effect of chemotherapy treatment. Analysis of the influence of adding the control drug agent into the model and how sensitive it is to the stochastic parameters is performed both in open-loop and closed-loop viewpoints through different numerical simulations

    Improving the mass determination of Galactic Cepheids

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    We have selected a sample of Galactic Cepheids for which accurate estimates of radii, distances, and photometric parameters are available. The comparison between their pulsation masses, based on new Period-Mass-Radius (PMR) relations, and their evolutionary masses, based on both optical and NIR Color-Magnitude (CM) diagrams, suggests that pulsation masses are on average of the order of 10% smaller than the evolutionary masses. Current pulsation masses show, at fixed radius, a strongly reduced dispersion when compared with values published in literature.The increased precision in the pulsation masses is due to the fact that our predicted PMR relations based on nonlinear, convective Cepheid models present smaller standard deviations than PMR relations based on linear models. At the same time, the empirical radii of our Cepheid sample are typically accurate at the 5% level. Our evolutionary mass determinations are based on stellar models constructed by neglecting the effect of mass-loss during the He burning phase. Therefore, the difference between pulsation and evolutionary masses could be intrinsic and does not necessarily imply a problem with either evolutionary and/or nonlinear pulsation models. The marginal evidence of a trend in the difference between evolutionary and pulsation masses when moving from short to long-period Cepheids is also briefly discussed. The main finding of our investigation is that the long-standing Cepheid mass discrepancy seems now resolved at the 10% level either if account for canonical or mild convective core overshooting evolutionary models.Comment: 14 pages, 4 postscript figures, accepted for publication on ApJ Letter

    Uncertainty and Margin Study for IMRT, VMAT, and Proton Beam Therapy for Treatment After Radical Prostatectomy

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    Purpose/Objective(s): To compare the uncertainties of 3D dose distributions, caused by the geometrical uncertainty of patient setup, in IMRT, VMAT, and proton plans for post-prostatectomy treatment. To test the effectiveness of a common margin recipe in these three types of treatment plans. American Society for Therapeutic Radiation Oncology (ASTRO) 52nd Annual Meeting October 31 - November 4, San Diego, C
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