A techno-economic evaluation of low-grade excess heat recovery and liquid desiccant-based temperature and humidity control in automotive paint shops

The paint shop is the most energy-intensive process in an automotive manufacturing plant, with air management systems that supply air to paint booths consuming the most energy. These systems are crucial for temperature and humidity control, in which they ensure the quality of the final product by preventing paint defects and thus avoid the additional cost of reworking. This is especially true for water-based paints, in which evaporation and film formation processes are influenced by the temperature and humidity of the surrounding air. This study aims to investigate the incorporation of liquid desiccant technology into a conventional air management system for paint shops operating in different climates, which presents the novelty of the study. The technology is promising because it can regulate humidity, act as a dehumidifier or humidifier depending on the demand and stores energy in a thermo-chemical form. In addition, waste heat sources available in the paint shop can be used for the regeneration of the liquid desiccant solution. The techno-economic evaluation of this novel process indicates that the proposed system can control the temperature and humidity of the supply air within the range required for optimal painting and achieve significant energy savings in both cold and hot/humid climates, with a reduction of 44.4% and 33.6% of the energy cost compared to the conventional operation and a payback period of 6.15 and 5.74 years respectively, using calcium chloride as the desiccant solution. The sensitivity analysis investigates the effect of the energy and carbon price on the performance of the system. It is concluded that the integration of liquid desiccant technology into conventional air management systems for paint booths has a huge potential to increase the energy-efficiency of automotive painting

Food waste handling in Malaysia and comparison with other Asian countries

The increasing amount of food waste in Malaysia in recent years has brought many environmental issues in the country where it affects the nation’s solid waste management framework. At the moment, the government is limited to other alternatives of food waste disposal besides the conventional landfill and incineration methods. This paper provides information on the current status of food waste handling, management, regulations, and policies in Malaysia. It helps to draw the problem and challenge to a clearer view in efforts of achieving sustainable and integrative food waste handling in the country

Prior Cancer Is Associated with Lower Atherosclerotic Cardiovascular Disease Risk at First Acute Myocardial Infarction

BACKGROUND: Patients with cancer are at increased risk of acute myocardial infarction (AMI). It is unclear if the Atherosclerotic Cardiovascular Disease (ASCVD) risk score at incident AMI is reflective of this higher risk in patients with prior cancer than those without. METHODS: We linked nationwide AMI and cancer registries from 2008 to 2019. A total of 18,200 eligible patients with ASCVD risk score calculated at incident AMI were identified (1086 prior cancer; 17,114 no cancer). RESULTS: At incident AMI, age-standardized mean ASCVD risk was lower in the prior cancer group (18.6%) than no cancer group (20.9%) (p < 0.001). Prior to incident AMI, smoking, hypertension, hyperlipidemia and diabetes mellitus were better controlled in the prior cancer group. However post-AMI, prior cancer was associated with lower guideline-directed medical therapy usage and higher all-cause mortality (adjusted hazard ratio 1.85, 95% confidence interval 1.66-2.07). CONCLUSIONS: AMI occurred despite better control of cardiovascular risk factors and lower age-standardized estimated mean 10-year ASCVD risk among patients with prior cancer than no cancer. Prior cancer was associated with lower guideline-directed medical therapy post-AMI and higher mortality

Compost feedstock characteristics and ratio modelling for organic waste materials co-composting in Malaysia

In Malaysia, large amounts of organic materials, which lead to disposal problems, are generated from agricultural residues especially from palm oil industries. Increasing landfill costs and regulations, which limit many types of waste accepted at landfills, have increased the interest in composting as a component of waste management. The objectives of this study were to characterize compost feedstock properties of common organic waste materials available in Malaysia. Thus, a ratio modelling of matching ingredients for empty fruit bunches (EFBs) co-composting using different organic materials in Malaysia was done. Organic waste materials with a C/N ratio of<30 can be applied as a nitrogen source in EFB co-composting. The outcome of this study suggested that the percentage of EFB ranged between 50% and 60%, which is considered as the ideal mixing ratio in EFB co-composting. Conclusively, EFB can be utilized in composting if appropriate feedstock in term of physical and chemical characteristics is coordinated in the co-composting process

Supply Chain Based Solution to Prevent Fuel Tax Evasion: Proof of Concept Final Report

The goal of this research was to provide a proof-of-concept (POC) system for preventing non-taxable (non-highway diesel use) or low-taxable (jet fuel) petrochemical products from being blended with taxable fuel products and preventing taxable fuel products from cross-jurisdiction evasion. The research worked to fill the need to validate the legitimacy of individual loads, offloads, and movements by integrating and validating, on a near-real-time basis, information from global positioning system (GPS), valve sensors, level sensors, and fuel-marker sensors

Pasting and physical properties of green banana flours and pastas

Viscosity and physical properties of flours and pastas prepared from four cultivars of green bananas (namely Pisang Berangan, Pisang Nangka, Pisang Tanduk, and Pisang Nipah) have been evaluated. The moisture content and water activity of banana flours were found in the range of 7.71%-8.50% wet basis and 0.33-0.37, respectively. The peak viscosity of banana flours were observed in the order of Pisang Tanduk > Pisang Nipah > Pisang Nangka > Pisang Berangan. The water activity and colour of pastas prepared from banana flours were lower and darker compared to wheat pasta. The firmness of banana flour dried pastas were observed significantly higher than wheat pasta, with Pisang Berangan pasta recorded the highest value of 446.53 ± 7.44 g. Among the green banana cultivars, pastas prepared from Pisang Nipah and Pisang Nangka flours are recommended for consumer who is preferred of bright colour and firm texture cooked pastas

Transitioning or tinkering at a net-zero economy? Introducing an assessment framework for industrial cluster decarbonisation in the United Kingdom

Decarbonising industrial clusters globally is crucial in combating climate change and is integral to the United Kingdom's ambition of achieving a net-zero economy by 2050. The absence of holistic frameworks that provide a nuanced understanding of the broad spectrum of mitigation options for decarbonising industrial clusters, coupled with a deficiency in real-world empirical evaluations, present a substantial barrier in realising set targets for reducing CO2 emissions. The increasing fragmentations in industrial decarbonisation frameworks further exacerbates the challenge of identifying the necessary and sufficient actions for achieving optimal industrial decarbonisation and net-zero transitioning. This paper proposes an assessment framework for industrial cluster decarbonisation and aims to address the existing gaps, particularly in the assessment of social, economic, and environmental impact of any deployed technology. Focusing on a wide range of technologies, sectoral strategies, and regional dynamics, the proposed framework is driven by specific key performance indicators and a comprehensive human and data-driven analytical approach that reflects descriptive, diagnostic, and prescriptive insights on the Teesside industrial cluster in the United Kingdom. Following the validation of the proposed assessment framework, empirical findings from 30 in-depth semi-structured interviews, two workshops, focus group meetings and the literature on industrial decarbonisation reveal that the framework recognises the complex interplay of technology and decision-making in the transition to net-zero of industrial clusters. The article concludes that the proposed assessment framework can assist stakeholders, policymakers, and researchers in assessing the impacts of energy transition, which is critical to policy design and decision-making while also contributing to achieving sustainable decarbonisation goals

HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease

DNA damage contributes to brain aging and neurodegenerative diseases. However, the factors stimulating DNA repair to stave off functional decline remain obscure. We show that HDAC1 modulates OGG1-initated 8-oxoguanine (8-oxoG) repair in the brain. HDAC1-deficient mice display age-associated DNA damage accumulation and cognitive impairment. HDAC1 stimulates OGG1, a DNA glycosylase known to remove 8-oxoG lesions that are associated with transcriptional repression. HDAC1 deficiency causes impaired OGG1 activity, 8-oxoG accumulation at the promoters of genes critical for brain function, and transcriptional repression. Moreover, we observe elevated 8-oxoG along with reduced HDAC1 activity and downregulation of a similar gene set in the 5XFAD mouse model of Alzheimer’s disease. Notably, pharmacological activation of HDAC1 alleviates the deleterious effects of 8-oxoG in aged wild-type and 5XFAD mice. Our work uncovers important roles for HDAC1 in 8-oxoG repair and highlights the therapeutic potential of HDAC1 activation to counter functional decline in brain aging and neurodegeneration

HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease

DNA damage contributes to brain aging and neurodegenerative diseases. However, the factors stimulating DNA repair to stave off functional decline remain obscure. We show that HDAC1 modulates OGG1-initated 8-oxoguanine (8-oxoG) repair in the brain. HDAC1-deficient mice display age-associated DNA damage accumulation and cognitive impairment. HDAC1 stimulates OGG1, a DNA glycosylase known to remove 8-oxoG lesions that are associated with transcriptional repression. HDAC1 deficiency causes impaired OGG1 activity, 8-oxoG accumulation at the promoters of genes critical for brain function, and transcriptional repression. Moreover, we observe elevated 8-oxoG along with reduced HDAC1 activity and downregulation of a similar gene set in the 5XFAD mouse model of Alzheimer’s disease. Notably, pharmacological activation of HDAC1 alleviates the deleterious effects of 8-oxoG in aged wild-type and 5XFAD mice. Our work uncovers important roles for HDAC1 in 8-oxoG repair and highlights the therapeutic potential of HDAC1 activation to counter functional decline in brain aging and neurodegeneration