128 research outputs found
Electroweak baryogenesis induced by a scalar field
A cosmological pseudoscalar field coupled to hypercharge topological number
density can exponentially amplify hyperelectric and hypermagnetic fields while
coherently rolling or oscillating, leading to the formation of a time-dependent
condensate of topological number density. The topological condensate can be
converted, under certain conditions, into baryons in sufficient quantity to
explain the observed baryon asymmetry in the universe. The amplified
hypermagnetic field can perhaps sufficiently strengthen the electroweak phase
transition, and by doing so, save any pre-existing baryon number asymmetry from
extinction.Comment: 8 pages, 4 figure
The Cosmic Microwave Background and Helical Magnetic Fields: the tensor mode
We study the effect of a possible helicity component of a primordial magnetic
field on the tensor part of the cosmic microwave background temperature
anisotropies and polarization. We give analytical approximations for the tensor
contributions induced by helicity, discussing their amplitude and spectral
index in dependence of the power spectrum of the primordial magnetic field. We
find that an helical magnetic field creates a parity odd component of gravity
waves inducing parity odd polarization signals. However, only if the magnetic
field is close to scale invariant and if its helical part is close to maximal,
the effect is sufficiently large to be observable. We also discuss the
implications of causality on the magnetic field spectrum.Comment: We have corrected a normalisation error which was pointed out to us
by Antony Lewis. It enhances our limits on the magnetic fields by
(2\pi)^{3/4} ~
Re-Inventing Adherence: Toward a Patient-Centered Model of Care for Drug-Resistant Tuberculosis and HIV
BACKGROUND—Despite renewed focus on molecular tuberculosis (TB) diagnostics and new antimycobacterial agents, treatment outcomes for patients co-infected with drug-resistant TB and human immunodeficiency virus (HIV) remain dismal, in part due to lack of focus on medication adherence as part of a patient-centered continuum of care.
OBJECTIVE—To review current barriers to drug-resistant TB-HIV treatment and propose an alternative model to conventional approaches to treatment support.
DISCUSSION—Current national TB control programs rely heavily on directly observed therapy (DOT) as the centerpiece of treatment delivery and adherence support. Medication adherence and care for drug-resistant TB-HIV could be improved by fully implementing team-based patient-centered care, empowering patients through counseling and support, maintaining a rights-based approach while acknowledging the responsibility of health care systems in providing comprehensive care, and prioritizing critical research gaps.
CONCLUSION—It is time to re-invent our understanding of adherence in drug-resistant TB and HIV by focusing attention on the complex clinical, behavioral, social, and structural needs of affected patients and communities
Large-scale magnetic fields from inflation in dilaton electromagnetism
The generation of large-scale magnetic fields is studied in dilaton
electromagnetism in inflationary cosmology, taking into account the dilaton's
evolution throughout inflation and reheating until it is stabilized with
possible entropy production. It is shown that large-scale magnetic fields with
observationally interesting strength at the present time could be generated if
the conformal invariance of the Maxwell theory is broken through the coupling
between the dilaton and electromagnetic fields in such a way that the resultant
quantum fluctuations in the magnetic field has a nearly scale-invariant
spectrum. If this condition is met, the amplitude of the generated magnetic
field could be sufficiently large even in the case huge amount of entropy is
produced with the dilution factor as the dilaton decays.Comment: 28 pages, 5 figures, the version accepted for publication in Phys.
Rev. D; some references are adde
Primordial Hypermagnetic Knots
Topologically non-trivial configurations of the hypermagnetic flux lines lead
to the formation of hypermagnetic knots (HK) whose decay might seed the Baryon
Asymmetry of the Universe (BAU).HK can be dynamically generated provided a
topologically trivial (i.e. stochastic) distribution of flux lines is already
present in the symmetric phase of the electroweak (EW) theory. In spite of the
mechanism generating the HK, their typical size must exceed the diffusivity
length scale. In the minimal standard model (MSM) (but not necessarily in its
supersymmetric extension) HK are washed out. A classical hypermagnetic
background in the symmetric phase of the EW theory can produce interesting
amounts of gravitational radiation.Comment: 4 pages in Revtex style, 2 figure
Magnetic field generation from non-equilibrium phase transitions
We study the generation of magnetic fields during the stage of particle
production resulting from spinodal instabilities during phase transitions out
of equilibrium. The main premise is that long-wavelength instabilities that
drive the phase transition lead to strong non-equilibrium charge and current
fluctuations which generate electromagnetic fields. We present a formulation
based on the non-equilibrium Schwinger-Dyson equations that leads to an exact
expression for the spectrum of electromagnetic fields valid for general
theories and cosmological backgrounds and whose main ingredient is the
transverse photon polarization out of equilibrium. This formulation includes
the dissipative effects of the conductivity in the medium. As a prelude to
cosmology we study magnetogenesis in Minkowski space-time in a theory of N
charged scalar fields to lowest order in the gauge coupling and to leading
order in the large N within two scenarios of cosmological relevance. The
long-wavelength power spectrum for electric and magnetic fields at the end of
the phase transition is obtained explicitly.
It follows that equipartition between electric and magnetic fields does not
hold out of equilibrium. In the case of a transition from a high temperature
phase, the conductivity of the medium severely hinders the generation of
magnetic fields, however the magnetic fields generated are correlated on scales
of the order of the domain size, which is much larger than the magnetic
diffusion length. Implications of the results to cosmological phase transitions
driven by spinodal unstabilities are discussed.Comment: Preprint no. LPTHE 02-55, 30 pages, latex, 2 eps figures. Added one
reference. To appear in Phys. Rev.
Large scale magnetogenesis from a non-equilibrium phase transition in the radiation dominated era
We study the generation of large scale primordial magnetic fields by a
cosmological phase transition during the radiation dominated era. The setting
is a theory of N charged scalar fields coupled to an abelian gauge field, that
undergoes a phase transition at a critical temperature much larger than the
electroweak scale. The dynamics after the transition features two distinct
stages: a spinodal regime dominated by linear long-wavelength instabilities,
and a scaling stage in which the non-linearities and backreaction of the scalar
fields are dominant. This second stage describes the growth of horizon sized
domains. We implement a recently introduced formulation to obtain the spectrum
of magnetic fields that includes the dissipative effects of the plasma. We find
that large scale magnetogenesis is very efficient during the scaling regime.
The ratio between the energy density on scales larger than L and that in the
background radiation r(L,T) = rho_B(L,T)/rho_{cmb}(T) is r(L,T) \sim 10^{-34}
at the Electroweak scale and r(L,T) \sim 10^{-14} at the QCD scale for L \sim 1
Mpc. The resulting spectrum is insensitive to the magnetic diffusion length. We
conjecture that a similar mechanism could be operative after the QCD chiral
phase transition.Comment: LaTex, 25 pages, no figures, to appear in Phys. Rev.
Primordial magnetic fields from inflation?
The hot plasma above the electroweak scale contains (hyper) charged scalar
particles which are coupled to Abelian gauge fields. Scalars may interact with
gravity in a non-conformally invariant way and thus their fluctuations can be
amplified during inflation. These fluctuations lead to creation of electric
currents and produce inhomogeneous distribution of charge density, resulting in
the generation of cosmological magnetic fields. We address the question whether
these fields can be coherent at large scales so that they may seed the galactic
magnetic fields. Depending upon the mass of the charged scalar and upon various
cosmological (critical fraction of energy density in matter, Hubble constant)
and particle physics parameters we found that the magnetic fields generated in
this way are much larger than vacuum fluctuations. However, their amplitude on
cosmological distances is found to be too small for seeding the galactic
magnetic fields.Comment: 32 pages in RevTex styl
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Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with Autism
Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) are often comorbid and share behavioural-cognitive abnormalities in sustained attention. A key question is whether this shared cognitive phenotype is based on common or different underlying pathophysiologies. To elucidate this question, we compared 20 boys with ADHD to 20 age and IQ matched ASD and 20 healthy boys using functional magnetic resonance imaging (fMRI) during a parametrically modulated vigilance task with a progressively increasing load of sustained attention. ADHD and ASD boys had significantly reduced activation relative to controls in bilateral striato–thalamic regions, left dorsolateral prefrontal cortex (DLPFC) and superior parietal cortex. Both groups also displayed significantly increased precuneus activation relative to controls. Precuneus was negatively correlated with the DLPFC activation, and progressively more deactivated with increasing attention load in controls, but not patients, suggesting problems with deactivation of a task-related default mode network in both disorders. However, left DLPFC underactivation was significantly more pronounced in ADHD relative to ASD boys, which furthermore was associated with sustained performance measures that were only impaired in ADHD patients. ASD boys, on the other hand, had disorder-specific enhanced cerebellar activation relative to both ADHD and control boys, presumably reflecting compensation. The findings show that ADHD and ASD boys have both shared and disorder-specific abnormalities in brain function during sustained attention. Shared deficits were in fronto–striato–parietal activation and default mode suppression. Differences were a more severe DLPFC dysfunction in ADHD and a disorder-specific fronto–striato–cerebellar dysregulation in ASD
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