Understanding Health Risks for Adolescents in Protective Custody

Children in child welfare protective custody (e.g., foster care) are known to have increased health concerns compared to children not in protective custody. The poor health documented for children in protective custody persists well into adulthood; young adults who emancipate from protective custody report poorer health, lower quality of life, and increased health risk behaviors compared to young adults in the general population. This includes increased mental health concerns, substance use, sexually transmitted infections, unintended pregnancy, and HIV diagnosis. Identifying youth in protective custody with mental health concerns, chronic medical conditions, and increased health risk behaviors while they remain in custody would provide the opportunity to target prevention and intervention efforts to curtail poor health outcomes while youth are still connected to health and social services. This study leveraged linked electronic health records and child welfare administrative records for 351 youth ages 15 and older to identify young people in custody who were experiencing mental health conditions, chronic medical conditions, and health risk behaviors (e.g., substance use, sexual risk). Results indicate that 41.6% of youth have a mental health diagnosis, with depression and behavior disorders most common. Additionally, 41.3% of youth experience chronic medical conditions, primarily allergies, obesity, and vision and hearing concerns. Finally, 39.6% of youth use substances and 37.0% engage in risky sexual behaviors. Predictors of health risks were examined. Those findings indicate that women, those with longer lengths of stay and more times in custody, and those in independent living and conjugate care settings are at greatest risk for mental health conditions, chronic medical conditions, and health risk behaviors. Results suggest a need to ensure that youth remain connected to health and mental health safety nets, with particular attention needed for adolescents in care for longer and/or those placed in non-family style settings. Understanding who is at risk is critical for developing interventions and policies to target youth who are most vulnerable for increased health concerns that can be implemented while they are in custody and are available to receive services

Vasopressin attenuates ischemia-reperfusion injury via reduction of oxidative stress and inhibition of mitochondrial permeability transition pore opening in rat hearts

Aim of this study was to investigate the involvement of the mitochondrial permeability transition pore (MPTP) and oxidative stress in the cardioprotective effect of vasopressin (AVP) on ischemia/reperfusion (I/R) injury. Anesthetized male wistar rats were subjected to regional 30 min ischemia and 120 min reperfusion and randomly divided into nine groups: (1) Control; saline was administered intravenously before ischemia, (2) vasopressin was administrated 10 min prior to ischemia, (3, 4) Atractyloside as MPTP opener, was injected 5 min prior to reperfusion without and with vasopressin, (5, 6) Cyclosporine A as a MPTP closer, was injected 5 min prior to reperfusion without and with vasopressin, (7) mitochondria were isolated from control group and CaCl2 was added as MPTP opener and swelling inducer, (8) isolated mitochondria from Control hearts was incubated with Cyclosporine A before adding the CaCl2 (9) CaCl2 was added to isolated mitochondria from vasopressin group. Infusion of vasopressin decreased infarct size (18.6±1.7% vs. control group 37.6±2.4%), biochemical parameters [LDH (Lactate Dehydrogenase), CK-MB (Creatine Kinase-MB) and MDA (Malondialdehyde) plasma levels, PAB (Prooxidant-antioxidant balance)] compared to control group. Atactyloside suppressed the cardioprotective effect of vasopressin (32.5±1.9% vs. 18.6±1.7%) but administration of the Cyclosporine A without and with vasopressin significantly reduced infarct size to 17.7±4% (P<0.001) and 22.7±3% (P<0.01) respectively, vs. 37.6±2.4% in control group. Also, vasopressin, similar to Cyclosporine A, led to decrease in CaCl2-induced swelling. It seems that vasopressin through antioxidant effect and MPTP inhibition has created a cardioprotection against ischemia/reperfusion injuries. © 2015 Elsevier B.V. All rights reserved

Role of mindfulness, psychological flexibility and integrative self-knowledge on psychological well-being among the university students

Background: Studies has shown the effect on environmental conditions on psychological well-being. In this regard, psychological characteristics have an important role. This study aimed to investigate the role of mindfulness, psychological flexibility and integrative self -knowledge amonge the university students. Material and Methods: This cross-sectional study was performed on the students of Kashan university of medical sciences (n=300) and based on quota sampling, a number of students (n=241) were selected based on the faculty and the major of the study. The administered tools were Ryff scale of psychological well-being (RSPWB-18), mindfulness (MAAS), acceptance and actions (AAQ-II) questionnaires and integrative self-knowledge scale (ISKS). Finally the data were analyzed using correlation and stepwise regression. Results: Pearson correlation disclosed a positive and considerable relation between mindfulness, integrative self-knowledge, psychological flexibility and psychological well-being. In addition, the findings showed significant role of mindfulness, integrative self-knowledge and psychological flexibility to predict the psychological well-being of the students; so these variables can predict 21 of psychological wellbeing changes. Conclusion: This study disclosed that the mindfulness, psychological flexibility and integrative self -knowledge can in part specify the variance of psychological well-being

Modelling cellphone trace travel mode with neural networks using transit smartcard and home interview survey data

This study proposes a framework to impute travel mode for trips identified from cellphone traces by developing a deep neural network model. In our framework, we use the trips from a home interview survey and transit smartcard data, for which the travel mode is known, to create a set of artificial pseudo-cellphone traces. The generated artificial pseudo-cellphone traces with known mode are then used to train a deep neural network classifier. We further apply the trained model to infer travel modes for the cellphone traces from cellular network data. The empirical case study region is Montevideo, Uruguay, where high-quality data are available for all three types of data used in the analysis: a large dataset of cellphone traces, a large dataset of public transit smartcard transactions, and a small household travel survey. The results can be used to create an enhanced representation of origin-destination trip-making in the region by time of day and travel mode

College Student Perceptions on Campus Alcohol Policies and Consumption Patterns

Environmental strategies for colleges and universities to reduce alcohol consumption among their students include the development and enforcement of campus alcohol policies. This study examines students\u27 knowledge and attitudes toward campus alcohol policies and how they relate to alcohol consumption and alcohol social norms. A sample of 422 freshman students was surveyed during their first month at a 4-year public college. Findings indicated that the majority of students (89%) were aware of campus policies, yet of those who were aware, less than half (44%) were accepting of these campus rules and regulations. In addition, the majority (79%) of students drank at social events, despite this behavior is in direct violation of campus alcohol policies. However, those who supported campus rules consumed significantly less alcohol at social events than those who opposed or had no opinion of the rules. Also, those who supported the rules perceived that their peers and students, in general, consumed significantly less alcohol at social events than those who were opposed or had no opinion. This outcome supports the premise established by several theories of behavior change including the theory of planned behavior, which states that behavior is influenced less by knowledge than by attitude and intention

Fly fauna of livestock’ s of Marvdasht County of Fars Province in the South of Iran

Flies damage the livestock industry in many ways, including damages, physical disturbances, the transmissions of pathogens and the emergence of problems for livestock like Myiasis. In this research, the fauna of flies of Marvdasht County was investigating, which is one of the central counties of Fars province in southern Iran. In this study, a total of 20 species of flies from 6 families and 15 genera have been identified and reported. The species collected are as follows: Muscidae: Musca domestica Linnaeus, 1758, Musca autumnalis* De Geer, 1776, Stomoxys calci-trans** Linnaeus, 1758, Haematobia irritans** Linnaeus, 1758 Fanniidae: Fannia canicularis* Linnaeus, 1761 Calliphoridae: Calliphora vomitoria* Linnaeus, 1758, Chrysomya albiceps* Wiedemann, 1819, Lu-cilia caesar* Linnaeus, 1758, Lucilia sericata* Meigen, 1826, Lucilia cuprina* Wiedemann, 1830 Sarcophagidae: Sarcophaga africa* Wiedemann, 1824, Sarcophaga aegyptica* Salem, 1935, Wohl-fahrtia magnifica** Schiner, 1862 Syrphidae: Eristalis tenax* Linnaeus, 1758, Syritta pipiens* Linnaeus, 1758, Eupeodes nuba* Wiedemann, 1830, Syrphus vitripennis** Meigen, 1822, Scaeva albomaculata* Macquart, 1842 Species identified with * for the first time in the county and the species marked with ** are reported for the first time from the Fars province

Evaluation of nanocarrier targeted drug delivery of capecitabine-PAMAM dendrimer complex in a mice colorectal cancer model

Capecitabine, an effective anticancer drug in colorectal cancer chemotherapy, may create adverse side effects on healthy tissues. In the present study, we first induced colon adenocarcinoma with azoxymethane, a carcinogen agent, and then investigated the potentiality of polyamidoamine (PAMAM) dendrimer to improve capecitabine therapeutic index and decrease its adverse side effects on healthy tissues like liver and bone marrow. Other variables such as nanoparticle concentrations have also been investigated. Drug loading concentration (DLC) and encapsulation efficiency (EE) were calculated for capecitabine/dendrimer complex. Experimental results showed an increase in DLC percentage resulted from elevated capecitabine/dendrimer ratio. Capecitabine/dendrimer complex could reduce tumor size and adverse side effects in comparison with free capecitabine form. © 2016 Tehran University of Medical Sciences. All rights reserved

The calculation of the effective interaction parameter in LDA+U method by linear response approach for Fe(OH)2

In this paper we have investigated the electronic properties of Fe(OH)2 hydroxide by using the LSDA+U as well as the generalized gradient approximation. Our calculations for the iron-hydroxide show that the LSDA results are greatly at variance with experimental findings. On the other hand we have shown that LSDA+U is capable of opening a gap at the Fermi level resulting in insulating ground state in agreement with experimental observations