Development of the Postpartum Smoking Questionnaire (PPSQ)

Cigarette smoking is the leading preventable cause of death in the United States. Smoking also accounts for significant morbidity for others exposed to environmental tobacco smoke. Many women stop smoking during pregnancy. Most women relapse to smoking following delivery, yet postpartum smoking issues have received little attention. The purpose of this study was to develop and test an instrument, the Postpartum Smoking Questionnaire (PPSQ) using Ajzen\u27s Theory of Planned Behavior. The belief-based items of the PPSR-Q were developed following content analysis of 35 individual, structured elicitation study interviews with postpartum women in the military healthcare system. Beliefs that prevented women from smoking included: worrying about the health of family members due to one\u27s own smoking, wanting to be a positive role model for children, and wanting to live longer. Stress management, addiction, and getting a break from the baby were reported as modal beliefs that contributed to postpartum smoking. Pilot testing of the PPSR-Q was conducted using test-retest reliability and item-to-total score correlation techniques. Suggested nursing interventions are presented based on the elicitation study results. Following further development and psychometric testing, the PPSQ will be used to guide the development, implementation, and evaluation of effective, targeted behavioral interventions that will reduce postpartum smoking rates

Academic Advising Methods and First-Year Full-Time Community College Student Achievement

Poor student achievement at some community colleges results in low retention and graduation rates. Addressing the problem of unpreparedness for college with good academic advising may help to improve student achievement. The purpose of this study was to determine whether there is a difference in the academic achievement of 1st year full-time (FYFT) community college students, based on having received 1 semester of any of 4 different academic advising methods (prescriptive, developmental, intrusive, proactive) while controlling for high school grade point average (GPA). Bandura\u27s social learning theory was used as the theoretical framework. A quantitative research method, deploying 1 research question and 5 hypotheses, was used to guide the examination of a sample of 349 archived data records of Fall 2016 FYFT students at a community college in the northeastern United States. The study included a categorical (factor) and a metric (covariate) measures of variables; therefore, a 1-way ANCOVA was used to estimate the effect of the academic advising method on student achievement. The findings showed no significant difference in FYFT student GPA, based on having received academic advising in general or any method of academic advising, during the 1st semester of enrollment. Despite these findings, the literature supports academic advising as critical for improving GPA, implying that further research is needed to adequately determine trends in student achievement related to advising over more than 1 semester at the college studied. By understanding the difference in the academic achievement of FYFT students based on having received academic advising consistently, academic advisors will have information that can potentially enhance student achievement and increase students\u27 chances of graduating, thus promoting positive social change

A Comparison of Phycocyanins from Three Different Species of Cyanobacteria Employing Resonance-Enhanced Coherent Anti-Stokes Raman Spectroscopy

Resonance-enhanced coherent anti-Stokes Raman spectra are recorded for monomers and trimers of phycocyanin from three different cyanobacteria: Westiellopsis prolifica, Mastigocladus laminosus and Spirulina platensis. It is shown that upon aggregation from monomer to trimer the electronic structures of both the α84 and β84 chromophores are changed. The spectra of the trimers originating from S. platensis and M. laminosus are very similar to each other, but distinctly different from the spectrum of W. prolifica

Genomic and geographical structure of human cytomegalovirus

Human cytomegalovirus (CMV) has infected humans since the origin of our species and currently infects most of the world’s population. Variability between CMV genomes is the highest of any human herpesvirus, yet large portions of the genome are conserved. Here, we show that the genome encodes 74 regions of relatively high variability each with 2 to 8 alleles. We then identified two patterns in the CMV genome. Conserved parts of the genome and a minority (32) of variable regions show geographic population structure with evidence for African or European clustering, although hybrid strains are present. We find no evidence that geographic segregation has been driven by host immune pressure affecting known antigenic sites. Forty-two variable regions show no geographical structure, with similar allele distributions across different continental populations. These “nongeographical” regions are significantly enriched for genes encoding immunomodulatory functions suggesting a core functional importance. We hypothesize that at least two CMV founder populations account for the geographical differences that are largely seen in the conserved portions of the genome, although the timing of separation and direction of spread between the two are not clear. In contrast, the similar allele frequencies among 42 variable regions of the genome, irrespective of geographical origin, are indicative of a second evolutionary process, namely balancing selection that may preserve properties critical to CMV biological function. Given that genetic differences between CMVs are postulated to alter immunogenicity and potentially function, understanding these two evolutionary processes could contribute important information for the development of globally effective vaccines and the identification of novel drug targets

Developing Biomarkers for Methamphetamine Addiction

There are an estimated 11.7 million methamphetamine (MA) abusers in the United States and epidemics of MA addiction are occurring worldwide. In our human laboratory and outpatient clinical trials we use innovative methods to quantify the severity of MA addiction and test biomarkers that may predict response to therapy or risk of relapse. One potential biomarker of addiction is the quantity of abused drug intake. Qualitative urinalysis is used in clinical trials and during treatment but provides only a binary outcome measure of abuse. Using non-pharmacologic doses of deuterium labeled l-MA we have developed a continuous quantitative measure to estimate the bioavailable amount of MA addicts ingest. Brain Derived Neurotrophic Factor is a neurotrophin that encourages growth and differentiation of new neurons and synapses. Low BDNF levels are seen in many addictive disorders and BDNF is elevated in recovering MA addicts, suggesting BDNF may be a marker of MA addiction. We are investigating the effects of controlled doses of MA on BDNF levels and gene regulation and measuring BDNF in our clinical trials. We believe both patients and clinical researches will benefit from the addition of new, objective and quantifiable outcome measures that reflect disease severity and recovery from addiction

Model evaluation of marine primary organic aerosol emission schemes

In this study, several marine primary organic aerosol (POA) emission schemes have been evaluated using the GEOS-Chem chemical transport model in order to provide guidance for their implementation in air quality and climate models. These emission schemes, based on varying dependencies of chlorophyll <i>a</i> concentration ([chl <i>a</i>]) and 10 m wind speed (<i>U</i><sub>10</sub>), have large differences in their magnitude, spatial distribution, and seasonality. Model comparison with weekly and monthly mean values of the organic aerosol mass concentration at two coastal sites shows that the source function exclusively related to [chl <i>a</i>] does a better job replicating surface observations. Sensitivity simulations in which the negative <i>U</i><sub>10</sub> and positive [chl <i>a</i>] dependence of the organic mass fraction of sea spray aerosol are enhanced show improved prediction of the seasonality of the marine POA concentrations. A top-down estimate of submicron marine POA emissions based on the parameterization that compares best to the observed weekly and monthly mean values of marine organic aerosol surface concentrations has a global average emission rate of 6.3 Tg yr<sup>−1</sup>. Evaluation of existing marine POA source functions against a case study during which marine POA contributed the major fraction of submicron aerosol mass shows that none of the existing parameterizations are able to reproduce the hourly-averaged observations. Our calculations suggest that in order to capture episodic events and short-term variability in submicron marine POA concentration over the ocean, new source functions need to be developed that are grounded in the physical processes unique to the organic fraction of sea spray aerosol

The Engine Is the Message: Videogame Infrastructure and the Future of Digital Platforms

On January 18, Microsoft revealed its $68.7 billion deal to acquire videogame publisher Activision Blizzard. The acquisition was pitched as an investment towards “metaverse platforms” that gaming would play a key role in developing. Journalists speculated about the increasing consolidation of the videogame industry and whether blockbuster franchises would be locked into Microsoft’s platforms and subscription services. Commentary on the metaverse weighed in on how toxicity and harassment in game industry workplaces such as Activision Blizzard might relate to issues of trust and safety in virtual worlds such as Meta’s Horizon Worlds. Seemingly above the fray of platform strategy, market speculation, and corporate scandal, New Yorker writer Kyle Chayka (2022) tweeted as a matter of fact: “video game infrastructure and tools are increasingly going to take over all digital platforms”. This panel contextualizes discussions about the business and aesthetics of 3D platforms in the infrastructural work of game engines, which routinely integrate databases, file formats, web protocols, and translational algorithms. We trace public debates and corporate statements over representation and governance, equity and inclusion (Bosworth 2021) to the techniques, technologies, and practices that enable massive real-time 3D digital spaces to flow and transact. We also highlight the growing intertwinement between game engine development companies and related content ecosystems, such as the Epic Games Store and the Unreal Engine, and Epic’s and Unity’s Asset Stores. This panel investigates how digital systems are designed to regulate technical interoperability and its implications for creative practice and cultural production. Together, these papers map how power and capital become centralized and distributed throughout the back end of the metaverse, and politicize how social practices and subjectivities are negotiated through technological architecture

Strategies to Implement an Online Academic Advising Unit: Increasing Access, equity, support and success in students

Los estudiantes que toman cursos en línea requieren el mismo nivel de servicios para estudiantes que aquellos en los cursos presenciales (SACSCOC, 2014). Como parte del esfuerzo para cumplir con las guías de acreditación en los Estados Unidos y a manera de satisfacer las necesidades de los estudiantes en línea, se implementó una división de consejería académica 100% en línea. Este servicio es imprescindible para garantizar que los estudiantes tengan acceso a un apoyo académico oportuno, a la vez que minimizan los riesgos asociados con el desgaste. Utilizando un enfoque de asesoramiento intruso, los consejeros académicos calendarizan sesiones de asesoramiento con los estudiantes, inmediatamente experimentan dificultades en un curso en línea. El asesoramiento académico en línea es iniciado por Alertas Tempranas "Early Alerts", estos son referidos electrónicos iniciados por el profesor y cubren una variedad de situaciones que enfrentan los estudiantes mientras asisten a clases. Estas son acciones basadas en datos que aprovechan la colaboración entre las divisiones de Asuntos Académicos y de Servicios al Estudiante. Para garantizar que el servicio se brinde a los estudiantes de manera oportuna (sin demora), los asesores en línea están disponibles en tres husos horarios. El asesoramiento se provee (se produce) a través de una multiplicidad de canales que incluyen llamadas telefónicas, correos electrónicos, videoconferencias, foros de discusión y chat, lo que permite a los estudiantes ser exitosos en sus actividades académicas. La ponencia discute el marco utilizado para implementar una operación de consejeria académica 100% en línea para el TCC Connect Campus, un nuevo campus en el Sistema Tarrant County College, en apoyo de estudiantes no tradicionales, inscritos en el programa de eLearning, programas acelerados (Weekend College, 7 semanas, términos mensuales “Monthly Starts”) y “Degree Pathways” que le provee a los estudiantes la oportunidad de completar un título de grado asociado en menos de dos años. Los asistentes recibirán información y estrategias sobre la necesidad de implementar un programa dedicado de consejería/asesoramiento académico para los estudiantes en línea.Students who take online courses require the same level of services for students as those in face-to-face classes (SACSCOC, 2014). As part of the effort to comply with accreditation guidelines in the United States and to meet the needs of online students, a 100% online academic counseling division was implemented. This service is essential to ensure that students have access to timely academic support while minimizing the risks associated with attrition. Using an intrusive counseling approach, online academic advisors schedule advising sessions with students immediately experiencing difficulties in an online course. Online academic advising sessions are initiated by Early Alerts; these are electronic referrals initiated by the professor and cover a variety of situations faced by students while attending classes. These are actions based on data that take advantage of collaboration between the Academic Affairs and Student Services divisions. To ensure that the service is provided to students promptly, online advising sessions are made possible across three-time zones. Advising is provided through a multiplicity of channels that include telephone calls, emails, video conferencing, discussion forums and chat, which allows students to be successful in their academic activities. The paper discusses the framework used to implement a 100% online academic counseling operation for the TCC Connect Campus, a new campus in the Tarrant County College System, in support of non-traditional students enrolled in the eLearning program, accelerated programs ( Weekend College, 7 weeks, monthly "Monthly Starts" terms) and Degree Pathways that provide students the opportunity to complete an associate's degree in less than two years. Attendees will receive information and strategies on the need to implement a dedicated academic advising program for online student

Global distribution and climate forcing of marine organic aerosol: 1. Model improvements and evaluation

Marine organic aerosol emissions have been implemented and evaluated within the National Center of Atmospheric Research (NCAR)'s Community Atmosphere Model (CAM5) with the Pacific Northwest National Laboratory's 7-mode Modal Aerosol Module (MAM-7). Emissions of marine primary organic aerosols (POA), phytoplankton-produced isoprene- and monoterpenes-derived secondary organic aerosols (SOA) and methane sulfonate (MS<sup>−</sup>) are shown to affect surface concentrations of organic aerosols in remote marine regions. Global emissions of submicron marine POA is estimated to be 7.9 and 9.4 Tg yr<sup>−1</sup>, for the Gantt et al. (2011) and Vignati et al. (2010) emission parameterizations, respectively. Marine sources of SOA and particulate MS<sup>−</sup> (containing both sulfur and carbon atoms) contribute an additional 0.2 and 5.1 Tg yr<sup>−1</sup>, respectively. Widespread areas over productive waters of the Northern Atlantic, Northern Pacific, and the Southern Ocean show marine-source submicron organic aerosol surface concentrations of 100 ng m<sup>−3</sup>, with values up to 400 ng m<sup>−3</sup> over biologically productive areas. Comparison of long-term surface observations of water insoluble organic matter (WIOM) with POA concentrations from the two emission parameterizations shows that despite revealed discrepancies (often more than a factor of 2), both Gantt et al. (2011) and Vignati et al. (2010) formulations are able to capture the magnitude of marine organic aerosol concentrations, with the Gantt et al. (2011) parameterization attaining better seasonality. Model simulations show that the mixing state of the marine POA can impact the surface number concentration of cloud condensation nuclei (CCN). The largest increases (up to 20%) in CCN (at a supersaturation (<i>S</i>) of 0.2%) number concentration are obtained over biologically productive ocean waters when marine organic aerosol is assumed to be externally mixed with sea-salt. Assuming marine organics are internally-mixed with sea-salt provides diverse results with increases and decreases in the concentration of CCN over different parts of the ocean. The sign of the CCN change due to the addition of marine organics to sea-salt aerosol is determined by the relative significance of the increase in mean modal diameter due to addition of mass, and the decrease in particle hygroscopicity due to compositional changes in marine aerosol. Based on emerging evidence for increased CCN concentration over biologically active surface ocean areas/periods, our study suggests that treatment of sea spray in global climate models (GCMs) as an internal mixture of marine organic aerosols and sea-salt will likely lead to an underestimation in CCN number concentration

Genomic and geographical structure of human cytomegalovirus

Human cytomegalovirus (CMV) has infected humans since the origin of our species and currently infects most of the world’s population. Variability between CMV genomes is the highest of any human herpesvirus, yet large portions of the genome are conserved. Here, we show that the genome encodes 74 regions of relatively high variability each with 2 to 8 alleles. We then identified two patterns in the CMV genome. Conserved parts of the genome and a minority (32) of variable regions show geographic population structure with evidence for African or European clustering, although hybrid strains are present. We find no evidence that geographic segregation has been driven by host immune pressure affecting known antigenic sites. Forty-two variable regions show no geographical structure, with similar allele distributions across different continental populations. These “nongeographical” regions are significantly enriched for genes encoding immunomodulatory functions suggesting a core functional importance. We hypothesize that at least two CMV founder populations account for the geographical differences that are largely seen in the conserved portions of the genome, although the timing of separation and direction of spread between the two are not clear. In contrast, the similar allele frequencies among 42 variable regions of the genome, irrespective of geographical origin, are indicative of a second evolutionary process, namely balancing selection that may preserve properties critical to CMV biological function. Given that genetic differences between CMVs are postulated to alter immunogenicity and potentially function, understanding these two evolutionary processes could contribute important information for the development of globally effective vaccines and the identification of novel drug targets