406 research outputs found
In Process Citation
Objectifs
Il semble exister une augmentation de la frĂ©quence et de la sĂ©vĂ©ritĂ© des hypospadias dans les pays dĂ©veloppĂ©s. La cause principalement Ă©voquĂ©e est lâinfluence de lâenvironnement par lâutilisation croissante de produits phytosanitaire agissant comme des perturbateurs endocriniens. Nous avons donc rĂ©alisĂ© une Ă©tude comparant deux sĂ©ries dâhypospadias pris en charge dans notre centre Ă 20 ans dâintervalle, au sein dâune rĂ©gion viticole utilisant ces produits.
MĂ©thodes
Nous avons revu les comptes rendus opératoires des enfants opérés pour hypospadias sur 2 périodes de 10 ans, une premiÚre de 1980 à 1990 comparée à une seconde de 2004 à 2014. Les hypospadias ont été classés dans les 3 grades habituels de sévérité croissante : antérieur (balanique ou balano-préputial), moyen (formes péniennes) ou postérieur (scrotal ou périnéal).
RĂ©sultats
Le nombre total dâinterventions est passĂ© de 285 pour la pĂ©riode 1980â1990 à 389 pour 2004â2014, parmi lesquelles respectivement 262 et 356 pour une chirurgie premiĂšre, soit une augmentation de 37 %. Parmi ces premiĂšres interventions, les formes postĂ©rieures restaient stables, respectivement de 11 (4,2 %) en 1980â1990 à 13 (3,7 %) en 2004â2014 (NS). En revanche, la proportion de formes moyennes augmentait de 25,2 % Ă 40,6 % (p < 0,001) et celle des formes antĂ©rieures diminuait de 70,6 % Ă 56,1 % (p < 0,001). Notons que la natalitĂ© de notre rĂ©gion a lĂ©gĂšrement diminuĂ©e entre les 2 pĂ©riodes, passant de 10 617 en 1985 à 10 165 en 2009.
Conclusion
Le nombre dâenfants opĂ©rĂ©s pour hypospadias a significativement augmentĂ©, mĂȘme si la possible variation des recrutements entre ces pĂ©riodes rend toute conclusion difficile. LâĂ©valuation de la sĂ©vĂ©ritĂ© montre que les formes postĂ©rieures, trĂšs malformatives, ne changent pas au cours du temps ; nĂ©anmoins, la proportion des formes moyennes augmentent par rapport aux formes antĂ©rieures, par possible influence des perturbateurs endocriniens
Hygrothermal monitoring of replacement infill panels for historic timber-frame buildings: initial findings
Energy retrofits aim to improve the thermal performance of buildingsâ external envelopes. With buildings of traditional construction there exists the risk that these improvements may lead to interstitial condensation and moisture accumulation. For historic timber-framed buildings, this potentially exposes the embedded historic timbers to conditions favouring fungal decay and insect infestation. Hygrothermal digital simulations can assess this risk, but these have limitations, especially regarding the study of historic and traditional materials, due to a lack of accurate material data. The research presented in this paper therefore uses the monitoring of physical test panels to examine the performance of four different infill solutions. These are, traditional wattle and daub, a composite of wood fibre and wood wool boards, expanded cork board, and hempcrete. The article focuses on the design and construction of the test cell and presents initial results from the first year of monitoring, following the initial drying phase. These showed no evidence of interstitial condensation in any of the panel build-ups, with increases in moisture content correlating directly with climatic measurements of wind-driven rain. Infill materials with low moisture permeability were seen to produce higher moisture contents at the interface with the external render due to the concentration of moisture at this point. Those panels finished in the more moisture permeable lime-hemp plaster, overall present lower moisture contents, with reduced drying times. The use of perimeter, non-moisture permeable, sealants would appear to potentially trap moisture at the junction between infill and historic timber-frame. The monitoring work is ongoing
When is working memory important for arithmetic?: the impact of strategy and age
Our ability to perform arithmetic relies heavily on working memory, the manipulation and maintenance of information in mind. Previous research has found that in adults, procedural strategies, particularly counting, rely on working memory to a greater extent than retrieval strategies. During childhood there are changes in the types of strategies employed, as well as an increase in the accuracy and efficiency of strategy execution. As such it seems likely that the role of working memory in arithmetic may also change, however children and adults have never been directly compared. This study used traditional dual-task methodology, with the addition of a control load condition, to investigate the extent to which working memory requirements for different arithmetic strategies change with age between 9-11 years, 12-14 years and young adulthood. We showed that both children and adults employ working memory when solving arithmetic problems, no matter what strategy they choose. This study highlights the importance of considering working memory in understanding the difficulties that some children and adults have with mathematics, as well as the need to include working memory in theoretical models of mathematical cognition
The GRANDMA network in preparation for the fourth gravitational-wave observing run
GRANDMA is a world-wide collaboration with the primary scientific goal ofstudying gravitational-wave sources, discovering their electromagneticcounterparts and characterizing their emission. GRANDMA involves astronomers,astrophysicists, gravitational-wave physicists, and theorists. GRANDMA is now atruly global network of telescopes, with (so far) 30 telescopes in bothhemispheres. It incorporates a citizen science programme (Kilonova-Catcher)which constitutes an opportunity to spread the interest in time-domainastronomy. The telescope network is an heterogeneous set of already-existingobserving facilities that operate coordinated as a single observatory. Withinthe network there are wide-field imagers that can observe large areas of thesky to search for optical counterparts, narrow-field instruments that dotargeted searches within a predefined list of host-galaxy candidates, andlarger telescopes that are devoted to characterization and follow-up of theidentified counterparts. Here we present an overview of GRANDMA after the thirdobserving run of the LIGO/VIRGO gravitational-wave observatories in and its ongoing preparation for the forthcoming fourth observational campaign(O4). Additionally, we review the potential of GRANDMA for the discovery andfollow-up of other types of astronomical transients.<br
Ready for O4 II: GRANDMA Observations of Swift GRBs during eight-weeks of Spring 2022
We present a campaign designed to train the GRANDMA network and its
infrastructure to follow up on transient alerts and detect their early
afterglows. In preparation for O4 II campaign, we focused on GRB alerts as they
are expected to be an electromagnetic counterpart of gravitational-wave events.
Our goal was to improve our response to the alerts and start prompt
observations as soon as possible to better prepare the GRANDMA network for the
fourth observational run of LIGO-Virgo-Kagra (which started at the end of May
2023), and future missions such as SM. To receive, manage and send out
observational plans to our partner telescopes we set up dedicated
infrastructure and a rota of follow-up adcates were organized to guarantee
round-the-clock assistance to our telescope teams. To ensure a great number of
observations, we focused on Swift GRBs whose localization errors were generally
smaller than the GRANDMA telescopes' field of view. This allowed us to bypass
the transient identification process and focus on the reaction time and
efficiency of the network. During 'Ready for O4 II', 11 Swift/INTEGRAL GRB
triggers were selected, nine fields had been observed, and three afterglows
were detected (GRB 220403B, GRB 220427A, GRB 220514A), with 17 GRANDMA
telescopes and 17 amateur astronomers from the citizen science project
Kilonova-Catcher. Here we highlight the GRB 220427A analysis where our
long-term follow-up of the host galaxy allowed us to obtain a photometric
redshift of , its lightcurve elution, fit the decay slope of the
afterglows, and study the properties of the host galaxy
Aging, working memory capacity and the proactive control of recollection:An event-related potential study
The present study investigated the role of working memory capacity (WMC) in the control of recollection in young and older adults. We used electroencephalographic event-related potentials (ERPs) to examine the effects of age and of individual differences in WMC on the ability to prioritize recollection according to current goals. Targets in a recognition exclusion task were words encoded using two alternative decisions. The left parietal ERP old/new effect was used as an electrophysiological index of recollection, and the selectivity of recollection measured in terms of the difference in its magnitude according to whether recognized items were targets or non-targets. Young adults with higher WMC showed greater recollection selectivity than those with lower WMC, while older adults showed nonselective recollection which did not vary with WMC. The data suggest that aging impairs the ability to engage cognitive control effectively to prioritize what will be recollected
Multi-band analyses of the bright GRB~230812B and the associated SN2023pel
GRB~230812B is a bright and relatively nearby () long gamma-ray
burst that has generated significant interest in the community and therefore
has been subsequently observed over the entire electromagnetic spectrum. We
report over 80 observations in X-ray, ultraviolet, optical, infrared, and
sub-millimeter bands from the GRANDMA (Global Rapid Advanced Network for
Multi-messenger Addicts) network of observatories and from observational
partners. Adding complementary data from the literature, we then derive
essential physical parameters associated with the ejecta and external
properties (i.e. the geometry and environment) and compare with other analyses
of this event (e.g. Srinivasaragavan et al. 2023). We spectroscopically confirm
the presence of an associated supernova, SN2023pel, and we derive a
photospheric expansion velocity of v 17 km . We
analyze the photometric data first using empirical fits of the flux and then
with full Bayesian Inference. We again strongly establish the presence of a
supernova in the data, with an absolute peak r-band magnitude . We find a flux-stretching factor or relative brightness and a time-stretching factor ,
both compared to SN1998bw. Therefore, GRB 230812B appears to have a clear long
GRB-supernova association, as expected in the standard collapsar model.
However, as sometimes found in the afterglow modelling of such long GRBs, our
best fit model favours a very low density environment (). We also find small values for
the jet's core angle and
viewing angle. GRB 230812B/SN2023pel is one of the best characterized
afterglows with a distinctive supernova bump
GRANDMA and HXMT Observations of GRB 221009A -- the Standard-Luminosity Afterglow of a Hyper-Luminous Gamma-Ray Burst
GRB 221009A is the brightest Gamma-Ray Burst (GRB) detected in more than 50
years of study. In this paper, we present observations in the X-ray and optical
domains after the GRB obtained by the GRANDMA Collaboration (which includes
observations from more than 30 professional and amateur telescopes) and the
Insight-HXMT Collaboration. We study the optical afterglow with empirical
fitting from GRANDMA+HXMT data, augmented with data from the literature up to
60 days. We then model numerically, using a Bayesian approach, the GRANDMA and
HXMT-LE afterglow observations, that we augment with Swift-XRT and additional
optical/NIR observations reported in the literature. We find that the GRB
afterglow, extinguished by a large dust column, is most likely behind a
combination of a large Milky-Way dust column combined with moderate
low-metallicity dust in the host galaxy. Using the GRANDMA+HXMT-LE+XRT dataset,
we find that the simplest model, where the observed afterglow is produced by
synchrotron radiation at the forward external shock during the deceleration of
a top-hat relativistic jet by a uniform medium, fits the multi-wavelength
observations only moderately well, with a tension between the observed temporal
and spectral evolution. This tension is confirmed when using the extended
dataset. We find that the consideration of a jet structure (Gaussian or
power-law), the inclusion of synchrotron self-Compton emission, or the presence
of an underlying supernova do not improve the predictions, showing that the
modelling of GRB22109A will require going beyond the most standard GRB
afterglow model. Placed in the global context of GRB optical afterglows, we
find the afterglow of GRB 221009A is luminous but not extraordinarily so,
highlighting that some aspects of this GRB do not deviate from the global known
sample despite its extreme energetics and the peculiar afterglow evolution.Comment: Accepted to ApJL for the special issue, 37 pages, 23 pages main text,
6 tables, 13 figure
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