1,974 research outputs found

    Sorption vacuum trap

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    Modified sorption trap for use in high vacuum systems contains provisions for online regeneration of sorbent material. Trap is so constructed that it has a number of encapsulated resistance heaters and a valving and pumping device for removing gases from heated sorbing material. Excessive downtime is eliminated with this trap

    Sorption vacuum trap Patent

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    Describing sorption vacuum trap having housing with group of reentrant wall portions projecting into internal gas-pervious container filled with gas and vapor sorbent materia

    Research Brief: The Role of Tasks and Skills in Explaining the Disability Pay Gap

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    A disparity in pay exists between workers with and without disabilities. This gap persists even in analyses that control for a variety of factors and incorporate compensation benefits other than wages and salaries. To better understand the underlying sources of these differences, occupation-level data on employee skill and task requirements are considered. Evaluating the earnings gap with this additional information provides insights regarding the economic returns to certain workplace tasks and skills that may contribute to the earnings gap that we observe for people with disabilities

    Bionomics of a Greenbug Parasite Lysiphlebus testaceipes (Cresson)

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    The greenbug, Schizaphis graminum (Rondani), is a major pest to grain crops in the Great Plains states. In 1968, 7.3 X 106 acres of sorghum were infested in nine of these states. The loss of sorghum in Kansas alone was estimated at lJ.5 X 106 bushels. In 1969 and 1970 the combined South Dakota recorded sorghum yield and control losses were over $2.6 X io6 (USDA 1970 and 1971). The greenbug is an economic vector for diseases of winter wheat, barley, oats, sorghum, and cane. Severe infestations on winter wheat have led to reduced crop cover and soil erosion. S. graminum has evolved three biotypes, A, B, and C. Biotype C has been one of the main limiting factors to grain production, thriving over a wide temperature and plant host range. The greenbug has migrated northward to the central states each spring. There has been a natural time lag which has enabled establishment of the greenbug between its entrance in April and the parasite-predator build-up. Greenbug populations have been effectively reduced by topical applications of chemicals, often harsh to natural controls and poorly timed. Systemic insecticides are being tested for early, preventative and residual control. Such insecticides will possibly be less damaging to native greenbug predator and parasite populations, allowing their build-up while suppressing the greenbug numbers. A combination of biological and chemical controls may be the solution to improved production. The objectives of this project were to contribute to the knowledge of the biology of Lysiphlebus testaceipes (Cresson), considered to be an effective control of the greenbug, and to investigate the influence of certain systemic insecticides in sorghum, on the greenbug populations and on the greenbug predator and parasite populations. The influence of low temperature on successful parasite copulation and emergence was investigated under controlled environmental conditions, and the population studies, under field conditions

    Ionospheric simulator survey

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    Evaluation of D and E region ionospheric simulation technique

    Food Animal Veterinarians: Where We Came From and Where We Might Go

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    The history of veterinary medicine has been one of growth and adaptation to the needs of society. Today, the discipline relating to food animals is being challenged by various forces ranging from projected shortages of qualified personnel, to economic challenges and deficiencies in training future graduates. Despite these challenges, veterinarians interested in working with food animals have tremendous opportunities. Combining current interests and attention with a well-planned vision to shape the profession can likely ensure food animal veterinarian\u27s relevance and contributions to society

    Research Brief: Total Compensation Gaps are Distinct from Wage Gaps

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    While the disparity in wage and salary income between workers with and without disabilities is well documented in the literature, less is known about the gap in total compensation. Health insurance, mandated benefits, and days of leave for vacation or illness are examples of the additional forms of compensation that comprise roughly 30 percent of total hourly compensation costs by firms for workers

    Maximum tumor diameter is associated with event-free survival in PET-negative patients with stage I/IIA Hodgkin lymphoma.

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    Introduction: the high cure rates achieved in early-stage (ES) Hodgkin lymphoma (HL) are one of the great successes of hemato-oncology, but late treatment-related toxicity undermines long-term survival. Improving overall survival and quality of life further will require maintaining disease control while potentially de-escalating chemotherapy and/or omitting radiotherapy to reduce late toxicity. Accurate stratification of patients is required to facilitate individualized treatment approaches. Response assessment using 18F-fluorodeoxyglucose positron emission tomography (PET) is a powerful predictor of outcome in HL,1,2 and has been used in multiple studies, including the United Kingdom National Cancer Research Institute Randomised Phase III Trial to Determine the Role of FDG–PET Imaging in Clinical Stages IA/IIA Hodgkin’s Disease (UK NCRI RAPID) trial, to investigate whether patients achieving complete metabolic remission (CMR) can be treated with chemotherapy alone.3-5 These PET-adapted trials have demonstrated that omitting radiotherapy results in higher relapse rates, but without compromising overall survival.3-5 For the 75% of patients who achieved CMR in RAPID, neither baseline clinical risk stratification (favorable/unfavorable) nor PET (Deauville score 1/2) predicted disease relapse; additional biomarkers are needed.1 Tumor bulk has long been recognized as prognostic in HL,1,6 but there remains uncertainty about the significance and definition of bulk in the era of PET-adapted treatment.7 We performed a subsidiary analysis of RAPID to assess the prognostic value of baseline maximum tumor dimension (MTD) in patients achieving CMR. Methods: ee have previously reported the RAPID trial design, primary results, and outcomes according to pretreatment risk stratification and PET score.1,3 Patients were aged 16 to 75 years with untreated ES-HL and without B-symptoms or mediastinal bulk (mass > 1/3 internal mediastinal diameter at T5/6).6 Metabolic response after 3 cycles of ABVD chemotherapy (doxorubicin, bleomycin, vinblastine, and dacarbazine) was centrally assessed using PET (N = 562). Patients with CMR (ie, Deauville score 1-2) were randomly assigned to receive involved field radiotherapy (IFRT; n = 208) or no further therapy (NFT; n = 211). PET-positive patients (score, 3-5; n = 143) received a fourth cycle of ABVD and IFRT. Baseline disease assessment was performed by computed tomography, and bidimensional target lesion measurements were reported by local radiologists in millimeters. The association of baseline MTD with HL-related event-free survival (EFS: progression or HL-related death) and progression-free survival (PFS) (progression or any-cause death) was assessed using Kaplan-Meier and Cox regression analyses. Non-HL deaths were either related to primary treatment toxicity or occurred in HL remission.1 United Kingdom ethical approval for the RAPID trial was via the UK Multicentre Research ethics committee. Results and discussion: baseline patient characteristics have been previously described.1 Median age was 34 years (range, 16-75 years); 184 (37.4%) of 492 patients had unfavorable risk by European Organisation for Research and Treatment of Cancer criteria, and 155 (32.3%) of 480 by German Hodgkin Study Groupcriteria. Median MTD for patients achieving CMR was 3.0 cm (interquartile range, 2.0-4.0 cm) and 3.0 cm (interquartile range, 1.8-4.5 cm) in the NFT and IFRT groups, respectively, whereas PET-positive patients had a median MTD of 3.9 cm (interquartile range, 2.8-5.1 cm). After a median follow-up of 61.6 m, 44 HL progression events occurred: 21 NFT, 9 IFRT and 14 PET-positive. No patient received salvage treatment without documented progression. Only 5 HL-related deaths occurred (1 IFRT, 4 PET-positive), and 12 non-HL deaths (4 NFT, 6 IFRT, 2 PET-positive).1 For patients with CMR (N = 419), there was a strong association between MTD and EFS (hazard ratio [HR], 1.19; 95% confidence interval [CI], 1.02-1.39; P = .02), adjusting for treatment group, with an approximate 19% increase in HL risk per centimeter increase in MTD. The association was similar in both treatment groups (NFT HR, 1.20 [95% CI, 0.99-1.44; P = .06]; IFRT HR, 1.19 [95% CI, 0.92-1.55; P = .19]). The observed effect sizes did not markedly change after adjusting for baseline clinical risk factors, and similar results were observed for PFS (supplemental Table 1). In contrast, for PET-positive patients, there was no association between MTD and EFS (HR, 0.88; 95% CI, 0.70-1.11; P = .29) or PFS (HR, 0.87; 95% CI, 0.70-1.08; P = .21). In an exploratory analysis within the NFT group, MTD was dichotomized using increasing 1-cm intervals to investigate the relationship between MTD thresholds and EFS. The largest effect size was observed with an MTD threshold of ≥5 cm (Table 1). Similar results were observed for PFS; this threshold also performed best in time-dependent receiver operating characteristic curve analyses. It was not possible to assess MTD thresholds in the IFRT group with only 9 events. Among all randomized patients, 79 (18.9%) had MTD of ≥5 cm, the majority with mediastinal (n = 43), supraclavicular (n = 17), or cervical (n = 16) locations. Five-year EFS for patients with MTD of ≥5 cm randomly assigned to NFT and IFRT was 79.3% (n = 39; 95% CI, 66.6%-92.0%) and 94.9% (n = 40; 95% CI, 88.0%-100%), respectively (P = .03; Figure 1)

    Transition delay and drag reduction using biomimetically inspired surface waves

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    This paper explores the use of Two-Dimensional sinusoidal surface features to delay transition and/or reduce drag. The authors, in this paper demonstrated that the presence of low amplitude sinusoidal surface features might damp the disturbances in the laminar boundary layer, reduce wall shear stress and maintain laminar flow for longer than a conventional flat plate. The hypothesis of the paper is inspired by the simplification of the dermal denticle on the surface of the shark-skin. Simulations are carried out using the Transition SST model in FLUENT based on the evidences of the transition model being suitable for a wider variety of high curvature scenarios. The surface waves are simulated for different amplitudes and wavelengths and their impact on transition onset and drag reduction are quantified at different velocities. Results presented in this paper indicate that a transition delay of 10.8% and a drag reduction of 5.2% are achievable. Furthermore, this paper adds credence to the notion that biomimicry is a very promising avenue for future drag reducing methods
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