522 research outputs found
Counting Integer flows in Networks
This paper discusses new analytic algorithms and software for the enumeration
of all integer flows inside a network. Concrete applications abound in graph
theory \cite{Jaeger}, representation theory \cite{kirillov}, and statistics
\cite{persi}. Our methods clearly surpass traditional exhaustive enumeration
and other algorithms and can even yield formulas when the input data contains
some parameters. These methods are based on the study of rational functions
with poles on arrangements of hyperplanes
Essential Dynamics on Different Biological Systems: Fis Protein, tvMyb1 Transcriptional Factor and BACE1 Enzyme
Controle genético de alguns caracteres relacionados a cor da semente de feijão no cruzamento Rosinha x Esal 693.
A cor da semente do feijão, Phaseolus vulgaris L. (Leguminosae-Faboideae), é de grande importância para o consumo no Brasil, por isso, o conhecimento do seu controle genético, em um cruzamento particular, orienta no dimensionamento da população segregante para a seleção do fenótipo de interesse. Então, objetivou-se determinar o controle genético de alguns caracteres relacionados à cor da semente, a partir do cruzamento Rosinha x ESAL 693 (tipo carioca) e prever as chances de seleção dos fenótipos semelhantes aos das cultivares Carioca e Rosinha. Foram avaliadas as cores de fundo e a presença/ausência de listras e halos nas sementes produzidas em plantas F2 e em plantas das famílias F2:3. Constatou-se apenas um gene responsável pela ocorrência de listras na semente e outro pela cor bege clara ou escura de fundo da semente tipo carioca. Para os caracteres presença ou ausência de halo e tipo de semente igual ou diferente da cultivar Rosinha, foram identificados dois genes em cada caso. Excetuando-se a presença de listra, certamente estão também envolvidos genes modificadores no controle dos demais caracteres. Considerando todos os caracteres, esperam-se 11,26% das plantas F2 produzindo sementes do tipo carioca ideal e 12,82% das plantas com sementes do tipo rosinha
Limit Synchronization in Markov Decision Processes
Markov decision processes (MDP) are finite-state systems with both strategic
and probabilistic choices. After fixing a strategy, an MDP produces a sequence
of probability distributions over states. The sequence is eventually
synchronizing if the probability mass accumulates in a single state, possibly
in the limit. Precisely, for 0 <= p <= 1 the sequence is p-synchronizing if a
probability distribution in the sequence assigns probability at least p to some
state, and we distinguish three synchronization modes: (i) sure winning if
there exists a strategy that produces a 1-synchronizing sequence; (ii)
almost-sure winning if there exists a strategy that produces a sequence that
is, for all epsilon > 0, a (1-epsilon)-synchronizing sequence; (iii) limit-sure
winning if for all epsilon > 0, there exists a strategy that produces a
(1-epsilon)-synchronizing sequence.
We consider the problem of deciding whether an MDP is sure, almost-sure,
limit-sure winning, and we establish the decidability and optimal complexity
for all modes, as well as the memory requirements for winning strategies. Our
main contributions are as follows: (a) for each winning modes we present
characterizations that give a PSPACE complexity for the decision problems, and
we establish matching PSPACE lower bounds; (b) we show that for sure winning
strategies, exponential memory is sufficient and may be necessary, and that in
general infinite memory is necessary for almost-sure winning, and unbounded
memory is necessary for limit-sure winning; (c) along with our results, we
establish new complexity results for alternating finite automata over a
one-letter alphabet
On fundamental domains and volumes of hyperbolic Coxeter-Weyl groups
We present a simple method for determining the shape of fundamental domains
of generalized modular groups related to Weyl groups of hyperbolic Kac-Moody
algebras. These domains are given as subsets of certain generalized upper half
planes, on which the Weyl groups act via generalized modular transformations.
Our construction only requires the Cartan matrix of the underlying
finite-dimensional Lie algebra and the associated Coxeter labels as input
information. We present a simple formula for determining the volume of these
fundamental domains. This allows us to re-produce in a simple manner the known
values for these volumes previously obtained by other methods.Comment: v2: to be published in Lett Math Phys (reference added, typo
corrected
Clar Sextet Analysis of Triangular, Rectangular and Honeycomb Graphene Antidot Lattices
Pristine graphene is a semimetal and thus does not have a band gap. By making
a nanometer scale periodic array of holes in the graphene sheet a band gap may
form; the size of the gap is controllable by adjusting the parameters of the
lattice. The hole diameter, hole geometry, lattice geometry and the separation
of the holes are parameters that all play an important role in determining the
size of the band gap, which, for technological applications, should be at least
of the order of tenths of an eV. We investigate four different hole
configurations: the rectangular, the triangular, the rotated triangular and the
honeycomb lattice. It is found that the lattice geometry plays a crucial role
for size of the band gap: the triangular arrangement displays always a sizable
gap, while for the other types only particular hole separations lead to a large
gap. This observation is explained using Clar sextet theory, and we find that a
sufficient condition for a large gap is that the number of sextets exceeds one
third of the total number of hexagons in the unit cell. Furthermore, we
investigate non-isosceles triangular structures to probe the sensitivity of the
gap in triangular lattices to small changes in geometry
Being the father of a preterm-born child: Contemporary research and recommendations for NICU staff
Background: Most studies on parental reactions to a preterm birth and to hospitalization of the newborn in Neonatal Intensive Care Units (NICUs) have involved mothers. However, emotional responses and behaviors of fathers are equally important. Usually, the father is the first to meet the preterm newborn, to find out information about baby's condition and to communicate to the mother and other family members. In this context he is often left alone and can show psychological difficulties including affective disorders such as depression or anxiety. This paper describes the role of fathers in the NICU, the best practices to support fathers, and to explain the role of a psychologist in the NICU staff. Considerations and suggestions are provided on the difficulties encountered to support parents, with a focus on the role of fathers during the COVID-19 pandemic. Methods and Discussion: Considering contemporary research data and following an attachment perspective, we analyze the role of the father of a preterm-born child in the relation with the partner and in newborn caring. Research has shown that involving fathers in newborn care in NICU and at home is essential not only because it promotes the father/son attachment relationship and has positive effects on the psychological and somatic development of the newborn, but also for the health of the mother and whole family. Conclusion: Recommendations are provided to enhance the functions of fathers in the NICU, promote their involvement in the care of their infant, and interventions to prevent the manifestation of psychological suffering and/or perinatal affective disorders. The commitments of a psychologist in a NICU team are presented and require not only clinical skills, but also the ability to manage the emotional and relational difficulties of fathers, family and NICU staff. Considerations and suggestions are provided on the difficulties encountered by parents in the NICU during the COVID-19 pandemic
Suppression of SERK gene expression affects fungus tolerance and somatic embryogenesis in transgenic lettuce.
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A Combined Approach for Component-based Software Design
Component-based software development enables the construction of software artefacts by assembling binary units of production, distribution and deployment, the so-called software components. Several approaches addressing component-based development have been proposed recently. Most of these approaches are based on the Unified Modeling Language (UML). UML has been increasingly used in component-based development, despite some shortcomings associated with this language. This paper presents a methodology for the design of component-based applications that combines a modelbased approach with a UML-based approach. This combined approach tackles some of the limitations associated with UML, allowing a better control of the design process. Our combined approach is illustrated using some excerpts from a case study carried out on a chat application
A meta-analysis of comparative transcriptomic data reveals a set of key genes involved in the tolerance to abiotic stresses in rice
Several environmental factors, such as drought, salinity, and extreme temperatures, negatively affect plant growth and development, which leads to yield losses. The tolerance or sensitivity to abiotic stressors are the expression of a complex machinery involving molecular, biochemical, and physiological mechanisms. Here, a meta-analysis on previously published RNA-Seq data was performed to identify the genes conferring tolerance to chilling, osmotic, and salt stresses, by comparing the transcriptomic changes between tolerant and susceptible rice genotypes. Several genes encoding transcription factors (TFs) were identified, suggesting that abiotic stress tolerance involves upstream regulatory pathways. A gene co-expression network defined the metabolic and signalling pathways with a prominent role in the differentiation between tolerance and susceptibility: (i) the regulation of endogenous abscisic acid (ABA) levels, through the modulation of genes that are related to its biosynthesis/catabolism, (ii) the signalling pathways mediated by ABA and jasmonic acid, (iii) the activity of the \u201cDrought and Salt Tolerance\u201d TF, involved in the negative regulation of stomatal closure, and (iv) the regulation of flavonoid biosynthesis by specific MYB TFs. The identified genes represent putative key players for conferring tolerance to a broad range of abiotic stresses in rice; a fine-tuning of their expression seems to be crucial for rice plants to cope with environmental cues
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