39,270 research outputs found

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    This is a list of words or names that start with every digraph combination of 2 letters, except one. We have managed to put together a list 675 digraphs, with many different sources

    Automatic Pet Door and Magnetic Field Activation

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    Automatic pet doors are sold commercially as a completely built unit on today’s market. A low-cost design has been created to allow more flexible placement and construction of a door. This door is unlocked upon detection of a magnetic field originating from the pet’s collar. The required activation signal has been carefully characterized to allow customization of the door and collar for a particular purpose. Detailed information on the operating circuit and sensor activation are provided. Results of how the door is constructed and operated, as well as personalization, are presented

    Hyaluronic acid alters vessel behavior in CXCL12-treated HUVECs

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    Hyaluronic acid (HA) is a key component of the extracellular matrix known for absorbing water, swelling, and altering solid stress of tumors. HA’s anionic behavior may provide important biochemical effects toward tumor progression as well. Tumors obtain nutrients by relying on signaling molecules such as CXCL12 to recruit blood vessels and promote vessel leakage. Recent work suggests that additional positively-charged residues on CXCL12’s β and γ isoforms cause different biochemical functionality compared to the well-studied α isoform. These studies aimed to determine whether the presence of HA in a tumor’s microenvironment could alter the relative response strength of CXCL12’s various isoforms on blood vessel sprouting and apparent vascular permeability. The vessel microenvironment was modeled using a 3-channel microfluidic device with Human Umbilical Vein Endothelial Cells (HUVECs) in the outer channels forming monolayers against a 3D collagen or collagen/HA matrix in the center channel. HUVECs were cultured with media containing recombinant CXCL12 (α, β or γ). Results show that total HUVEC sprouting area follows an α>β>γ trend in isoform-treated HUVECs within a collagen matrix, matching the binding affinity order of CXCL12 to endothelial CXCR4 receptors. The presence of HA decreased overall sprouting response but shifted pro-angiogenic potency towards CXCL12’s γ isoform. Vascular permeability studies also showed an α>β>γ trend for HUVECs in collagen. With HA added, control and α-treated HUVECs became less permeable while γ-treated HUVECs became more permeable. Overall results suggest that an HA-infused collagen matrix facilitates γ isoform binding, leading to a stronger isoform-specific vessel response. Knowing how HA impacts CXCL12 isoform potency on vessels will help in the future design of CXCL12-targeted cancer therapies.The American Heart AssociationInstitute for Materials Research at OSULumley Engineering FundPelotoniaA one-year embargo was granted for this item.Academic Major: Chemical Engineerin

    Isogram Transdeletion Pyramid

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    There are many word articles on isograms and transdeletion pyramids, but there are none which talk about them combined, the isogram transdeletion pyramid

    Fusion Rules for Affine Kac-Moody Algebras

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    This is an expository introduction to fusion rules for affine Kac-Moody algebras, with major focus on the algorithmic aspects of their computation and the relationship with tensor product decompositions. Many explicit examples are included with figures illustrating the rank 2 cases. New results relating fusion coefficients to tensor product coefficients are proved, and a conjecture is given which shows that the Frenkel-Zhu affine fusion rule theorem can be seen as a beautiful generalization of the Parasarathy-Ranga Rao-Varadarajan tensor product theorem. Previous work of the author and collaborators on a different approach to fusion rules from elementary group theory is also explained.Comment: 43 pp, LateX, 18 postscript figures. Paper for my talk at the Ramanujan International Symposium on Kac-Moody Lie Algebras and Applications, ISKMAA-2002, Jan. 28-31, 2002, Chennai, India. Important references and comments added. Final version accepted for publication. Also available from ftp://ftp.math.binghamton.edu/pub/alex/Madras_Paper_Latex.ps.g
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