229 research outputs found
Economic Analysis of Cassava Production: Prospects and Challenges in Irepodun Local Government Area, Kwara State, Nigeria
This study was carried out to analyse cassava production, prospects and challenges in Irepodun local government area, Kwara State, Nigeria. It aimed to examine the determinant variables and determine the profitability level of cassava enterprises. The study was based on primary data obtained with the aid of structured questionnaire from 100 cassava farmers drawn through multi-stage sampling techniques from the study area. Data were analysed using descriptive statistics, ordinary least square (OLS) regression model and gross margin analysis. The result of the OLS regression estimates showed that farm size, cost of fertilizer application, farm size, herbicides, family and hired labour were significant variable affecting cassava production in the study area. Fertilizer, farm size and hired labour are significant at 1% while herbicide and family labour are significant at 10%. The study found that the average gross margin per hectare for cassava production in the study area was ₦24,749.28 ($65.30) with a gross benefit ratio of 1.38. This shows that for every ₦1 invested in the business of cassava production, there is a corresponding profit of ₦1.38. The major challenges identified in cassava enterprise are huge transportation cost, high cost of production, lack of improved cassava cultivars, and lack of market linkages. The study concluded despite the problem encountered in the study area, cassava production is profitable and can serve as a panacea for economic improvement of households. Therefore, the study recommends that basic inputs such as improved cassava varieties, herbicides and fertilizer should be made available at affordable price. Also, infrastructural facilities such as good road network and improve marketing channels should be provided in order to sustain current cassava production rate and economic gains from the production
AN EMPIRICAL ANALYSIS OF INFORMATION AND COMMUNICATION TECHNOLOGY (ICT) AND ECONOMIC GROWTH IN NIGERIA
Nigeria has witnessed a great change in information and communication technology (ICT) as a result of the liberalisation of the telecommunication sector in the country in the early 2000s coupled with high rate of economic growth. Consequently, this study examines the relationship and impact of ICT on economic growth in Nigeria. Using a secure internet server per 1 million, mobile cellular subscription per 100 people, and investment in telecoms with private sector participation (in current USD) as proxies for ICT, and GDP as proxy for economic growth for the period 1997 to 2016, the outcome of the autoregressive distributed lag (ARDL) reveals that there is a cointegration between ICT and economic growth, which establishes the existence of a long-run relationship between them. In the short run, only secure internet server per 1 million and mobile cellular subscription per 100 people have a positive and significant impact on economic growth, whereas investment in telecoms with private sector participation was not significant. The Granger causality test shows the bidirectional causality between secure internet server per 1 million and economic growth. The results suggest that there is a need for a strong political will to support an enabling environment and to propel the ease of doing business in the sector to attract private and foreign investment into the sector, as this would improve the secure internet server, increase the penetration of mobile usage to the rural communities, and increase the performance of other sectors of the economy that would foster the economic growth of Nigeria
Ocimum gratissimum Ameliorates Gentamicin-Induced Kidney Injury but Decreases Creatinine Clearance Following Sub-Chronic Administration in Rats
The effects of aqueous extract of Ocimum gratissimum leaf (AOGL) on the renal function of rats with gentamicin-induced
nephrotoxicity were investigated. This study involved the use of forty five (45) adult male Wistar rats (housed in separate
metabolic cages) such that graded doses of OAGL were administered to the experimental groups (p.o.) for 28 days after exposure
to gentamicin toxicity (100 mg/kg i.p.) for 1 week. At the end of the study, comparisons of some indices of renal function as well as
antioxidant status (GSH and TBARS) were made between the control, toxic and AOGL-treated groups at P < 0.05. The result
showed that gentamicin treatment caused significant increase (P < .05) in urine output, urea, creatinine, total protein, relative
kidney weight, and TBARS, as well as significant decrease (P < .05) in urine creatinine and GSH levels. Post-treatment with graded
doses of AOGL caused significant increase in food consumption, GSH, urine, and plasma creatinine, as well as significant decrease
(P < .05) in relative kidney weight, TBARS, and urine total protein. There was an appreciable difference in the kidney histology of
the AOGL-treated groups when compared with the toxic control. Hence, the extract has therapeutic potential in the management
of gentamicin-induced kidney injury, although a risk profile of renal dysfunction is not unlikely from 28 days of administration
as evident by the decrease in creatinine clearance
Ultrastructural comparison of three stingless bees species of Borneo
Three species of stingless bees were collected from Borneo. The species were Geniotrigona lacteifasciata (4 samples), Tetragonula melanocephala (2 samples) and Tetragonula sirindhornae (4 samples). Several features such as the morphology of mandible, the shape and size of corbiculae, and the hamuli number on both left and right wings were compared. Scanning electron microscopy (SEM) revealed all three species have the same structures of mandibles with two pointed tooth and one large blade, which could be considered as mildly aggressive. G. lacteifasciata showed a wider corbiculae compared to T. melanocephala and T. sirindhornae. The larger corbiculae is assumed to collect and carry heavier pollen load. SEM observation showed clear hamuli on both wings but with asymmetrical number for some. G. lactefasciata showed either 9 hamuli on both wings, or 9 hamuli on the left and 8 on the right wings, or 9 hamuli on the left and 10 hamuli on the right wings. T. melanocephala exhibited a similar number of hamuli, which was 5 hamuli on both wings. T. sirindhornae showed either 4 or 5 hamuli on both side of wings. It could be assumed that the stingless bees with more hamuli will fly further for foraging
Amelioration of Cadmium-Induced Nephropathy using Polyphenol-rich Extract of Vernonia amygdalina (Del.) Leaves in Rat Model
AIM: To determine the effects of polyphenol-rich extract of the leaves of Vernonia amygdalina (PEVA) in rats with Cd-induced nephropathy.MATERIALS AND METHODS: Sixty five male Wistar rats were divided into five groups as follows; Group 1 received distilled water throughout the period of study. Group 2 received 5 mg/kg body weight of cadmium (Cd), in the form of CdSO4, for five consecutive days via intraperitoneal route. Groups 3, 4 and 5 were pretreated with Cd as group 2 and thereafter received oral treatment of PEVA for 4 weeks at 100 mg/kg, 200 mg/kg and 400 mg/kg body weight, respectively.RESULTS: Exposure to Cd toxicity significantly induced deleterious alterations in plasma and urine levels of creatinine, urea and glucose as well as creatinine and urea clearance (p < 0.05) in the rat model. There was a significant disturbance in the antioxidant system as revealed by the levels of thiobarbituric acid reactive substance (TBARS) and reduced glutathione (GSH) (p < 0.05) in the kidney tissue of the rats. With marked improvements in renal histoarchitecture, PEVA treatment showed a duration and non dose-dependent ameliorative potential. CONCLUSION: PEVA treatment reversed the compromise of renal function that was induced by Cd toxicity in rat model
The Association between Peptic Ulcer Disease and Gastric Cancer: Results from the Stomach Cancer Pooling (StoP) Project Consortium
Background. Gastric cancer (GC) is the fifth most common type of cancer and the fourth most common cause of cancer-related mortality. Although the risk of GC and peptic ulcer disease (PUD) is known to be increased by H. pylori infection, evidence regarding the direct relationship between PUD and GC across ethnicities is inconclusive. Therefore, we investigated the association between PUD and GC in the Stomach cancer Pooling (StoP) consortium. Methods. History of peptic ulcer disease was collected using a structured questionnaire in 11 studies in the StoP consortium, including 4106 GC cases and 6922 controls. The two-stage individual-participant data meta-analysis approach was adopted to generate a priori. Unconditional logistic regression and Firth’s penalized maximum likelihood estimator were used to calculate study-specific odds ratios (ORs) and 95% confidence intervals (CIs) for the association between gastric ulcer (GU)/duodenal ulcer (DU) and risk of GC. Results. History of GU and DU was thoroughly reported and used in association analysis, respectively, by 487 cases (12.5%) and 276 controls (4.1%), and 253 cases (7.8%) and 318 controls (6.0%). We found that GU was associated with an increased risk of GC (OR = 3.04, 95% CI: 2.07–4.49). No association between DU and GC risk was observed (OR = 1.03, 95% CI: 0.77–1.39). Conclusions. In the pooled analysis of 11 case–control studies in a large consortium (i.e., the Stomach cancer Pooling (StoP) consortium), we found a positive association between GU and risk of GC and no association between DU and GC risk. © 2022 by the authors.This work is supported by Associazione Italiana per la Ricerca sul Cancro (AIRC), Project no. 21378 (Investigator Grant); Fondazione Italiana per la Ricerca sul Cancro (FIRC); Italian League for the Fight Against Cancer (LILT); European Cancer Prevention (ECP) Organization; and UPMC Start-up Grant (to HNL). P Paragomi was supported by a cancer research training grant from NIH (grant # T32CA186873)
The Association between Peptic Ulcer Disease and Gastric Cancer: Results from the Stomach Cancer Pooling (StoP) Project Consortium
Background. Gastric cancer (GC) is the fifth most common type of cancer and the fourth most common cause of cancer-related mortality. Although the risk of GC and peptic ulcer disease (PUD) is known to be increased by H. pylori infection, evidence regarding the direct relationship between PUD and GC across ethnicities is inconclusive. Therefore, we investigated the association between PUD and GC in the Stomach cancer Pooling (StoP) consortium. Methods. History of peptic ulcer disease was collected using a structured questionnaire in 11 studies in the StoP consortium, including 4106 GC cases and 6922 controls. The two-stage individual-participant data meta-analysis approach was adopted to generate a priori. Unconditional logistic regression and Firth’s penalized maximum likelihood estimator were used to calculate study-specific odds ratios (ORs) and 95% confidence intervals (CIs) for the association between gastric ulcer (GU)/duodenal ulcer (DU) and risk of GC. Results. History of GU and DU was thoroughly reported and used in association analysis, respectively, by 487 cases (12.5%) and 276 controls (4.1%), and 253 cases (7.8%) and 318 controls (6.0%). We found that GU was associated with an increased risk of GC (OR = 3.04, 95% CI: 2.07–4.49). No association between DU and GC risk was observed (OR = 1.03, 95% CI: 0.77–1.39). Conclusions. In the pooled analysis of 11 case–control studies in a large consortium (i.e., the Stomach cancer Pooling (StoP) consortium), we found a positive association between GU and risk of GC and no association between DU and GC risk
The enhanced naturally occurring radioactivity of negative ion clothing and attendant risk
The study investigates commercially available negative ion clothing, and evaluations are made using gamma-ray spectroscopy and Geant4 Monte Carlo simulations. Observed to contain naturally occurring radioactive material (NORM), evaluations are made of the radiological risk arising from the use of these as items of everyday wear, undergarments in particular. Organ doses from these were simulated using the MIRD5 mathematical female phantom, with the incorporation of dose conversion factors (DCFs). At 175 ± 26, 1732 ± 247, and 207 ± 38 Bq, for238U,232Th, and40K respectively, item code S05 was found to possess the greatest activity, while item code S07 was shown to have the least activity, at 2 ± 0.5 and 15 ± 2 Bq, and again for238U and232Th, respectively. Sample code S11 recorded least activity, at 29 ± 5 Bq, for40K. Among the clothing items, sample item code S05 offered the greatest concentrations of Th, U and Zr, with percentage means of 1.23 ± 0.1, 0.045 ± 0.001, and 1.29 ± 0.1, respectively, giving rise to an annual effective dose of 1.57 mSv/y assuming a nominal wearing period of 24 h per day. Accordingly, the annual public dose limit of 1 mSv can be exceeded by their use
Normal kidney size and its influencing factors - a 64-slice MDCT study of 1.040 asymptomatic patients
<p>Abstract</p> <p>Background</p> <p>Normal ultrasound values for pole-to-pole kidney length (LPP) are well established for children, but very little is known about normal kidney size and its influencing factors in adults. The objectives of this study were thus to establish normal CT values for kidney dimensions from a group of unselected patients, identify potential influencing factors, and to estimate their significance.</p> <p>Methods</p> <p>In multiphase thin-slice MDCTs of 2.068 kidneys in 1.040 adults, the kidney length pole to pole (LPP), parenchymal (PW) and cortical width (CW), position and rotation status of the kidneys, number of renal arteries, pyelon width and possible influencing factors that can be visualized, were recorded from a volume data set. For length measurements, axes were adjusted individually in double oblique planes using a 3D-software. Analyses of distribution, T-tests, ANOVA, correlation and multivariate regression analyses were performed.</p> <p>Results</p> <p>LPP was 108.5 ± 12.2 mm for the right, and 111.3 ± 12.6 mm for the left kidney (p < 0.0001 each). PW on the right side was 15.4 ± 2.8 mm, slightly less than 15.9 ± 2.7 mm on the left side (p < 0.0001), the CW was the same (6.6 ± 1.9 mm). The most significant independent predictors for LPP, CW, and PW were body size, BMI, age, and gender (p < 0.001 each). In men, the LPP increases up to the fifth decade of life (p < 0.01). It is also influenced by the position of the kidneys, stenoses and number of renal arteries (SRA/NRA), infarctions suffered, parapelvic cysts, and absence of the contralateral kidney; CW is influenced by age, position, parapelvic cysts, NRA and SRA, and the PW is influenced in addition by rotation status (p < 0.05 each). Depending on the most important factors, gender-specific normal values were indicated for these dimensions, the length and width in cross section, width of the renal pelvis, and parenchyma-renal pyelon ratio.</p> <p>Conclusions</p> <p>Due to the complex influences on kidney size, assessment should be made individually. The most important influencing factors are BMI, height, gender, age, position of the kidneys, stenoses and number of renal arteries.</p
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