268 research outputs found
Analyzing a Bose polaron across resonant interactions
Recently, two independent experiments reported the observation of long-lived
polarons in a Bose-Einstein condensate, providing an excellent setting to study
the generic scenario of a mobile impurity interacting with a quantum reservoir.
Here, we expand the experimental analysis by disentangling the effects of trap
inhomogeneities and the many-body continuum in one of these experiments. This
makes it possible to extract the energy of the polaron at a well-defined
density as a function of the interaction strength. Comparisons with quantum
Monte-Carlo as well as diagrammatic calculations show good agreement, and
provide a more detailed picture of the polaron properties at stronger
interactions than previously possible. Moreover, we develop a semi-classical
theory for the motional dynamics and three-body loss of the polarons, which
partly explains a previously unresolved discrepancy between theory and
experimental observations for repulsive interactions. Finally, we utilize
quantum Monte-Carlo calculations to demonstrate that the findings reported in
the two experiments are consistent with each other
Unstable Flow and Non-Monotonic Constitutive Equation of Transient Networks
We have measured the nonlinear rheological response of a model transient
network over a large range of steady shear rates. The system is built up from
an oil in water droplet microemulsion into which a telechelic polymer is
incorporated. The phase behaviour is characterized which comprises a liquid-gas
phase separation and a percolation threshold. The rheological measurements are
performed in the one phase region above the percolation line. Shear thinning is
observed for all samples, leading in most cases to an unstable stress response
at intermediate shear rates. We built up a very simple mean field model which
involves the reduction of the residence time of the stickers in the droplets
due to the chain tensions at high shear. The computed constitutive equation is
non-monotonic with a range where the stress is a decreasing function of the
rate, a feature that indeed makes homogeneous flows unstable. The computed the
flow curves compare well to the experiments.Comment: mai 200
Robust Phase Behavior of Model Transient networks
In order to study the viscoelastic properties of certain complex fluids which
are described in terms of a multiconnected transient network we have developed
a convenient model system composed of microemulsion droplets linked by
telechelic polymers. The phase behavior of such systems has two characteristic
features: a large monophasic region which consists of two sub-regions (a fluid
sol phase and a viscoelastic gel phase) separated by a percolation line and a
two phase region at low volume fraction with separation into a dilute sol phase
and a concentrated gel phase. From the plausible origin of these features we
expect them to be very similar in different systems. We describe here the phase
behavior of four different systems we prepared in order to vary the time scale
of the dynamical response of the transient network; they consist of the
combination of two oil(decane) in water microemulsions differing by the
stabilizing surfactant monolayer (Cetyl pyridinium chloride/octanol or
TX100/TX35) and of two telechelic polymers which are end-grafted poly (ethylene
oxide) chains, differing by the end-grafted hydrophobic aliphatic chains
(C12H25 or C18H37).Comment: April 9 200
OGLE-2005-BLG-018: Characterization of Full Physical and Orbital Parameters of a Gravitational Binary Lens
We present the analysis result of a gravitational binary-lensing event
OGLE-2005-BLG-018. The light curve of the event is characterized by 2 adjacent
strong features and a single weak feature separated from the strong features.
The light curve exhibits noticeable deviations from the best-fit model based on
standard binary parameters. To explain the deviation, we test models including
various higher-order effects of the motions of the observer, source, and lens.
From this, we find that it is necessary to account for the orbital motion of
the lens in describing the light curve. From modeling of the light curve
considering the parallax effect and Keplerian orbital motion, we are able to
measure not only the physical parameters but also a complete orbital solution
of the lens system. It is found that the event was produced by a binary lens
located in the Galactic bulge with a distance kpc from the Earth.
The individual lens components with masses and are separated with a semi-major axis of AU and
orbiting each other with a period yr. The event demonstrates
that it is possible to extract detailed information about binary lens systems
from well-resolved lensing light curves.Comment: 19 pages, 6 figure
An analogue of the Prolactin Releasing Peptide reduces obesity and promotes adult neurogenesis
Hypothalamic Adult Neurogenesis (hAN) has been implicated in regulating energy homeostasis. Adult-generated neurons and adult Neural Stem Cells (aNSCs) in the hypothalamus control food intake and body weight. Conversely, diet-induced obesity (DIO) by high fat diets (HFD) exerts adverse influence on hAN. However, the effects of anti-obesity compounds on hAN are not known. To address this, we administered a lipidized analogue of an anti-obesity neuropeptide, Prolactin Releasing Peptide (PrRP), so-called LiPR, to mice. In the HFD context, LiPR rescued the survival of adult-born hypothalamic neurons and increased the number of aNSCs by reducing their activation. LiPR also rescued the reduction of immature hippocampal neurons and modulated calcium dynamics in iPSC-derived human neurons. In addition, some of these neurogenic effects were exerted by another anti-obesity compound, Liraglutide. These results show for the first time that anti-obesity neuropeptides influence adult neurogenesis and suggest that the neurogenic process can serve as a target of anti-obesity pharmacotherapy
Ovaries of Tubificinae (Clitellata, Naididae) resemble ovary cords found in Hirudinea (Clitellata)
The ultrastructure of the ovaries and oogenesis was studied in three species of three genera of Tubificinae. The paired ovaries are small, conically shaped structures, connected to the intersegmental septum between segments X and XI by their narrow end. The ovaries are composed of syncytial cysts of germ cells interconnected by stable cytoplasmic bridges (ring canals) and surrounded by follicular cells. The architecture of the germ-line cysts is exactly the same as in all clitellate annelids studied to date, i.e. each cell in a cyst has only one ring canal connecting it to the central, anuclear cytoplasmic mass, the cytophore. The ovaries found in all of the species studied seem to be meroistic, i.e. the ultimate fate of germ cells within a cyst is different, and the majority of cells withdraw from meiosis and become nurse cells; the rest continue meiosis, gather macromolecules, cell organelles and storage material, and become oocytes. The ovaries are polarized; their narrow end contains mitotically dividing oogonia and germ cells entering the meiosis prophase; whereas within the middle and basal parts, nurse cells, a prominent cytophore and growing oocytes occur. During late previtellogenesis/early vitellogenesis, the oocytes detach from the cytophore and float in the coelom; they are usually enveloped by the peritoneal epithelium and associated with blood vessels. Generally, the organization of ovaries in all of the Tubificinae species studied resembles the polarized ovary cords found within the ovisacs of some Euhirudinea. The organization of ovaries and the course of oogenesis between the genera studied and other clitellate annelids are compared. Finally, it is suggested that germ-line cysts formation and the meroistic mode of oogenesis may be a primary character for all Clitellata
Impact Factor: outdated artefact or stepping-stone to journal certification?
A review of Garfield's journal impact factor and its specific implementation
as the Thomson Reuters Impact Factor reveals several weaknesses in this
commonly-used indicator of journal standing. Key limitations include the
mismatch between citing and cited documents, the deceptive display of three
decimals that belies the real precision, and the absence of confidence
intervals. These are minor issues that are easily amended and should be
corrected, but more substantive improvements are needed. There are indications
that the scientific community seeks and needs better certification of journal
procedures to improve the quality of published science. Comprehensive
certification of editorial and review procedures could help ensure adequate
procedures to detect duplicate and fraudulent submissions.Comment: 25 pages, 12 figures, 6 table
Governance Conditions for Improving Quality Drinking Water Resources: the Need for Enhancing Connectivity
Realising the water quality objectives of the European Water Framework Directive have appeared to stagnate over the last decade all across Europe because of their highly complex nature. In the literature, interactive governance approaches tend to be regarded as the best way of dealing with complex water issues, but so far little empirical evidence has been reported on this perspective in regard to water quality issues. In this paper we have analysed how conditions of governance contribute to the realisation of water quality objectives at different types of drinking water resources in the Netherlands. The analysis demonstrates the importance of addressing different hydrological scales, institutional levels and sectors and thus enhance connectivity in order to improve water quality. The two other important conditions of governance approaches for water quality improvement which were identified are the use of joint fact-finding to gain a shared perception of risks, and the use of explicit decision-making and close monitoring of outcomes (re. water quality improvement), both of which contribute to this enhanced connectivity
Determinantes Nacionais e Setoriais da Estrutura de Capital na América Latina
This study identified the role of the national environment (the Macroeconomy, Financial Development and
Institutional Quality) and industry characteristics (Munificence, Dynamism, Concentration, Life Cycle,
Technological Efficiency Dispersion, Product Quality Dispersion, Customer Bargaining Power and Supplier
Bargaining Power) on debt of 612 listed companies from 7 Latin American countries (Argentina, Brazil, Chile,
Colombia, Mexico, Peru and Venezuela). For comparison purposes, the analysis is also extended to 847 U.S.
companies. The period of study is 1996-2009 and the analysis employed a Hierarchical Linear Model, which
controls the effects according to the level of the variables (country, industry, time and firm). The results suggest
that Financial Development eases access to external funds and Institutional Quality is negatively related to firm
Leverage. The research also finds evidence that institutional quality can promote asymmetrical development
between stock markets and credit markets
Cumulative occupational lumbar load and lumbar disc disease â results of a German multi-center case-control study (EPILIFT)
Background The to date evidence for a dose-response relationship between physical workload and the development of lumbar disc diseases is limited. We therefore investigated the possible etiologic relevance of cumulative occupational lumbar load to lumbar disc diseases in a multi-center case-control study. Methods In four study regions in Germany (Frankfurt/Main, Freiburg, Halle/Saale, Regensburg), patients seeking medical care for pain associated with clinically and radiologically verified lumbar disc herniation (286 males, 278 females) or symptomatic lumbar disc narrowing (145 males, 206 females) were prospectively recruited. Population control subjects (453 males and 448 females) were drawn from the regional population registers. Cases and control subjects were between 25 and 70 years of age. In a structured personal interview, a complete occupational history was elicited to identify subjects with certain minimum workloads. On the basis of job task-specific supplementary surveys performed by technical experts, the situational lumbar load represented by the compressive force at the lumbosacral disc was determined via biomechanical model calculations for any working situation with object handling and load-intensive postures during the total working life. For this analysis, all manual handling of objects of about 5 kilograms or more and postures with trunk inclination of 20 degrees or more are included in the calculation of cumulative lumbar load. Confounder selection was based on biologic plausibility and on the change-in-estimate criterion. Odds ratios (OR) and 95% confidence intervals (CI) were calculated separately for men and women using unconditional logistic regression analysis, adjusted for age, region, and unemployment as major life event (in males) or psychosocial strain at work (in females), respectively. To further elucidate the contribution of past physical workload to the development of lumbar disc diseases, we performed lag-time analyses. Results We found a positive dose-response relationship between cumulative occupational lumbar load and lumbar disc herniation as well as lumbar disc narrowing among men and women. Even past lumbar load seems to contribute to the risk of lumbar disc disease. Conclusions According to our study, cumulative physical workload is related to lumbar disc diseases among men and women
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