Analysis of the environmental performance of life-cycle building waste management strategies in tertiary buildings

At urban level, the generation Municipal Solid Waste and Construction and Demolition Waste is mostly related to the life-cycle of buildings. An evaluation method based on Life Cycle Assessment methodology is presented in this paper to make an analysis of the environmental performance of different life-cycle building waste management strategies in tertiary buildings. As a case study, several waste management strategies considering a tertiary building located in the city of Zaragoza in Spain, are studied. The aim of the case study is to compare the environmental impacts, in terms of Global Warming Potential, of the scenarios proposed focussing on the waste minimisation and avoidance of landfilling of at least 10% for the Municipal Solid Waste generation during a building''s use stage, and Construction and Demolition Waste generated during its construction and end-of-life. In case of Municipal Solid Waste, the results show that when a recovery scenario includes energy recovery from the residual fraction of the mechanical-biological treatment plant in the form of Refuse Derived Fuel, greater benefits in terms of the Global Warming Potential are obtained than with current scenarios of landfill deposition of the residual fraction. On the other hand, in case of Construction and Demolition Waste, a similar situation can be observed in case of an increase of the recovery rates of metals

Information and Communications Technologies (ICTs) for energy efficiency in buildings: Review and analysis of results from EU pilot projects

Information and Communications Technologies (ICTs) can play a potential role in improving the energy performance of buildings by the implementation of effective solutions that take advantage of the energy interactions between all the elements included in a building. A revision of the 105 pilots implemented or under implementation in 18 projects in the area of ICTs for energy efficiency in buildings located in 23 European countries, through 88 cities with different types of climates, buildings and technologies have been carried out through documentary and field analysis of the energy, economic and social project results. These results have been extrapolated to assess the potential energy savings which could be expected at the EU level by implementing the solutions proposed by the projects. By the implementation of the different ICT solutions, buildings have achieved more than 20% energy savings. Pilots have demonstrated that the effectiveness of the ICT solution does not depend directly on the different climates where the solutions are implemented, but on several factors, such as the level of motivation, perceived thermal comfort, quality of social interaction and communication and ICT support

Randomized phase II study of fulvestrant plus palbociclib or placebo in endocrine-sensitive, hormone receptor-positive/HER2-advanced breast cancer: GEICAM/2014-12 (FLIPPER).

Este artículo ha sido publicado en la revista European Journal of Cancer. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Background: The potential benefit of adding palbociclib to fulvestrant as first-line treatment in hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative endocrine-sensitive advanced breast cancer (ABC) patients remains uncharacterized. Patients and methods: In this randomized (1:1), double-blind, phase II study, postmenopausal women with HR-positive, HER2-negative ABC with de novo metastatic disease or those who relapsed after >12 months of adjuvant endocrine therapy received palbociclib/fulvestrant or placebo/fulvestrant. Stratification was based on recurrent versus de novo metastatic disease and visceral involvement. The primary objective was one-year progression-free survival (PFS-1y) rate. The sample size was 190 patients. The two-sided alpha of 0.2, 80% of power to detect a difference between the arms, assuming PFS rates of 0.695 and 0.545 for palbociclib/fulvestrant and placebo/fulvestrant, respectively. Results: In total, 189 patients were randomized to palbociclib/fulvestrant ([n = 94] or placebo/fulvestrant [n = 95]). 45.5% and 60.3% of patients had de novo metastatic disease and visceral involvement, respectively. PFS-1y rates were 83.5% and 71.9% in the palbociclib/fulvestrant and placebo/fulvestrant arms, (HR 0.55, 80% CI 0.36-0.83, P = 0.064). The median PFS were 31.8 and 22.0 months for the palbociclib/fulvestrant and placebo/fulvestrant arms (aHR 0.48, 80% CI 0.37-0.64, P = 0.001). The most frequent grade 3-4 adverse events were neutropenia (68.1% vs. 0%), leucopenia (26.6% vs. 0%), anemia (3.2% vs. 0%), and lymphopenia (14.9% vs. 2.1%) for the palbociclib/fulvestrant and placebo/fulvestrant, respectively. The most frequent non-hematologic grade 3-4 adverse event was fatigue (4.3% vs. 0%). Conclusions: Palbociclib/fulvestrant demonstrated better PFS-1y rates and median PFS than placebo/fulvestrant in HR-positive/HER2-negative endocrine-sensitive ABC patients

35 Classifying Screenshots of Industrial Control System Using Transfer Learning and Fine-Tuning

Abstract—Industrial control systems are heavily dependant on security and monitoring protocols. For this purpose, monitoring tools take screenshots of control panels for later analysis.Classifying these screenshots into specific groups can be a time-consuming process, but it is crucial for the security tasks performed by manual operators. To solve this problem, we propose a pipeline based on deep learning to classify snapshots of industrial control panels into three categories: Internet Technologies (IT), Operation Technologies (OT), and others. We compare the results obtained with transfer learning and finetuning on nine convolutional neuronal networks pre-trained with the ImageNet dataset, testing them on a custom CRitical INFrastructure dataset (CRINF-300). Inception-ResNet-V2 obtains the best learning result with an F1-score of 98.32% on CRINF-300, while MobileNet-V1 obtained the best performance-speed tradeoff

La agricultura a tiempo parcial como sistema de vida en el medio rural andaluz

La generalización de la práctica de la agricultura a tiempo parcial es un fenómeno que se desarrolla a fuerte ritmo tras la Segunda Guerra Mundial. Esta dinámica social va a influir en la estructura productiva de las explotaciones así como en la evolución del campesinado. Su estudio es difícil, dadas las deficiencias estadísticas y las peculiaridades que presenta en cada región. En este caso, se analiza la ATP en Andalucía, destacando su estabilidad y su desvinculación del crecimiento industrial; en definitiva, su carácter preindustrial. En este caso, se da la conjunción de una dualidad latifundio/minifundio favorecida por la debilidad del sector industrial andaluz y el predominio en el medio rural de un poblamiento concentrado en grandes villas

Educar en la blogosfera

Se desarrolla un proyecto de innovación educativa que pretende conocer el potencial de los blogs como herramientas TIC adecuadas para el trabajo en el aula y para la realización de actividades colaborativas, creación de diarios on-line y publicación de comentarios sobre los artículos. Se estudia la transversalidad desde un enfoque basado en el uso práctico de las TIC, fomentando el uso educativo de Internet, sobretodo en lo referente a la búsqueda de contenidos, capacidad de contrastar información de diversas fuentes, capacidad de análisis crítico y debate on-line. Se realizarán trabajos en grupos a partir de los materiales obtenidos en la red, elaborando presentaciones y realizando puestas en común con el resto de los compañeros de la clase. La valoración del alumnado y del profesorado es muy positiva, tanto en lo referente a los blogs como herramienta didáctica, como al potencial de las presentaciones multimedia para la realización de los trabajos de carácter educativo. La participación del alumnado en proyectos Web de tipo educativo alternados con las clases tradicionales, contribuye a aumentar el interés por los temas tratados, mejora la actividad colaborativa, estimula la curiosidad y el deseo de involucrarse en las tareas propuestas y en general favorece el autoaprendizaje.Castilla y LeónConsejería de Educación. Dirección General de Universidades e Investigación; Monasterio de Nuestra Señora de Prado, Autovía Puente Colgante s. n.; 47071 Valladolid; +34983411881; +34983411939ES

Correction to: Efficacy of fulvestrant in the treatment of postmenopausal women with endocrine-resistant advanced breast cancer in routine clinical practice.

A sentence under 'Results' heading in the Abstract section was published incorrectly. The correct sentence should read as follows