EDUCAÇÃO SUPERIOR, POLÍTICAS PÚBLICAS E CONTEMPORANEIDADE: O DESAFIO DA INCLUSÃO SOCIAL

Qual é o papel da Universidade na contemporaneidade? Como ela vem desempenhando esse papel do ponto de vista das políticas afirmativas a exemplo as cotas e outras assemelhadas? Estas são algumas das questões levantadas a partir das leituras, discussões e análises ocorridas durante a realização da disciplina Estudos Avançados em Educação e Contemporaneidade do Programa de Pós-graduação em Educação e Contemporaneidade da Universidade do Estado da Bahia, categoria Doutorado. O presente trabalho busca refletir sobre a função social da Universidade na contemporaneidade na perspectiva da promoção da inclusão social por meio do ensino, pesquisa e extensão, abordando a relação entre a Educação Superior, inclusão social e as políticas públicas para essa etapa de educação, tendo como cenário as bases filosóficas, políticas e epistemológicas nas quais estão sendo construídas e sustentadas a contemporaneidade. Como base metodológica foi feita uma pesquisa bibliográfica a partir de autores que discutem temáticas necessárias ao apoio às reflexões ora apresentadas. Os resultados obtidos revelam uma universidade, ainda caminhante, mas que já se conscientiza de seu papel social, como proponente de políticas públicas para melhoria de qualidade de vida na sociedade

Effect of the intra-alveolar administration of dexamethasone on swelling, trismus, and pain after impacted lower third molar extraction:a randomized, double-blind clinical trial

To evaluate the efficacy of intra-alveolar administration of dexamethasone 4 mg in the control of edema, trismus, and pain resulting from the extraction of impacted lower third molars and the drug permeability through the oral mucosa by in silico prediction. The randomized, double-blind, split-mouth clinical trial included patients who had both impacted lower third molars in equivalent positions. Hemiarches were divided into control side when dexamethasone was administered orally and experimental side when dexamethasone was administered using the intra-alveolar route. Patients were evaluated considering edema, trismus, and pain. The permeability of dexamethasone through the oral mucosa was assessed by in silico prediction. Student?s t-test was selected for comparative analysis of edema and trismus, and the chi-square test analyzed the distribution of postoperative pain between the sides. There were no significant differences between the routes of administration in measuring symptoms between the pre and postoperative times (p>0.05). In silico prediction suggested that dexamethasone molecular characteristics facilitate intra-alveolar administration. Intra-alveolar administration had similar efficacy to oral administration in controlling symptoms of post-surgical inflammation of impacted lower third molars

Microbiological quality of minimally processed vegetables commercialized in Brasilia, DF, Brazil

This study evaluated the microbiological quality of minimally processed vegetables commercialized in the city of Brasilia, DF, Brazil. A total of 32 samples of different vegetables were purchased from 10 supermarkets. In most samples (78.1%) the populations of psychrotrophic bacteria had a high count ranging from 106 to 108 CFU/g. Thermotolerant coliforms were found in all samples, with populations higher than 102 MPN/g in 15 samples (46.9%). After molecular analyses, E. coli was identified in 16 samples (50.0%) and Salmonella spp. in 4 samples (12.5%). S. aureus was found in 14 samples (43.8%), with counts higher than 103 CFU/g in 4 samples (12.5%). The results obtained in this study showed that 16 samples (50%) were unfit for consumption according to Brazilian legislation. These results indicated the need of adoption of better hygienic practices in the production of minimally processed vegetables to improve quality and microbiological safety

Aplicação do gerenciamento de processos de negócios – BPM – ganhos e versatilidade na indústria de manufatura e serviços / Application of bussiness process management – BPM – gains and versatility in manufacturing industry and services

Business Process Management (BPM) é um conceito que tem sido amplamente discutido nas organizações e sistemas de gerenciamento de informação. Assim, o objetivo principal deste artigo é apresentar, por meio de uma revisão da literatura, o tema buscando ilustrar sua versatilidade de aplicação bem como ganhos em indicadores de produtividade e gestão em organizações de manufatura industrial e serviços. Deste modo, constatou-se a relevância dos processos como elemento essencial para o desempenho organizacional e que estes têm crescido devido à forte competição em relação ao custo, tempo, qualidade, aumento da complexidade do produto e requisitos dos clientes. Concluiu-se, por fim, que entender os processos de negócios em uma organização e direcionar ações estratégicas na busca pela potencialização dos benefícios, que contribuam para percepção de valores de produtos e serviços, entregues aos clientes é um desafio da gestão moderna

Antitumor effect and toxicity of free rhodium (II) citrate and rhodium (II) citrate-loaded maghemite nanoparticles in mice bearing breast cancer

Background: Magnetic fluids containing superparamagnetic iron oxide nanoparticles represent an attractive platform as nanocarriers in chemotherapy. Recently, we developed a formulation of maghemite nanoparticles coated with rhodium (II) citrate, which resulted in in vitro cytotoxicity enhanced up to 4.6 times when compared to free rhodium (II) citrate formulation on breast carcinoma cells. In this work, we evaluate the antitumor activity and toxicity induced by these formulations in Balb/c mice bearing orthotopic 4T1 breast carcinoma. Methods: Mice were evaluated with regard to the treatments’ toxicity through analyses of hemogram, serum levels of alanine aminotransferase, iron, and creatinine; DNA fragmentation and cell cycle of bone marrow cells; and liver, kidney and lung histology. In addition, the antitumor activity of rhodium (II) citrate and maghemite nanoparticles coated with rhodium (II) citrate was verified by tumor volume reduction, histology and immunohistochemistry. Results: Regarding the treatments’ toxicity, no experimental groups had alterations in levels of serum ALT or creatinine, and this suggestion was corroborated by the histopathologic examination of liver and kidney of mice. Moreover, DNA fragmentation frequency of bone marrow cells was lower than 15% in all experimental groups. On the other hand, the complexes rhodium (II) citrate-functionalized maghemite and free rhodium (II) citrate led to a marked growth inhibition of tumor and decrease in CD31 and Ki-67 staining. Conclusions: In summary, we demonstrated that both rhodium (II) citrate and maghemite nanoparticles coated with rhodium (II) citrate formulations exhibited antitumor effects against 4T1 metastatic breast cancer cell line following intratumoral administration. This antitumor effect was followed by inhibition of both cell proliferation and microvascularization and by tumor tissue injury characterized as necrosis and fibrosis. Remarkably, this is the first published report demonstrating the therapeutic efficacy of maghemite nanoparticles coated with rhodium (II) citrate. This treatment prolonged the survival period of treated mice without inducing apparent systemic toxicity, which strengthens its use for future breast cancer therapeutic applications

Analysis of the chlorine consumption for oxidation of the cyanobacteria species Microcystis aeruginosa

This study evaluated the chlorine consumption of the Microcystis aeruginosa species present in blooms in water supply sources, since the legislation requires the minimum maintenance of free residual chlorine should be 0.2 mg.L-1 or 2 mg.L-1 of combined residual chlorine and a residue from 3 to 5 mg.L-1 after 7 days. Chlorine gas analyzes were performed in laboratory scale: 8 dosages for 30 minutes and 24 hours tests and 7 dosages for 7 days. The results showed high chlorine consumption, what can be related to by-products formation of chlorination in the water treatment