26 research outputs found
Calibration of the AKARI Far-Infrared Imaging Fourier Transform Spectrometer
The Far-Infrared Surveyor (FIS) onboard the AKARI satellite has a
spectroscopic capability provided by a Fourier transform spectrometer
(FIS-FTS). FIS-FTS is the first space-borne imaging FTS dedicated to
far-infrared astronomical observations. We describe the calibration process of
the FIS-FTS and discuss its accuracy and reliability. The calibration is based
on the observational data of bright astronomical sources as well as two
instrumental sources. We have compared the FIS-FTS spectra with the spectra
obtained from the Long Wavelength Spectrometer (LWS) of the Infrared Space
Observatory (ISO) having a similar spectral coverage. The present calibration
method accurately reproduces the spectra of several solar system objects having
a reliable spectral model. Under this condition the relative uncertainty of the
calibration of the continuum is estimated to be 15% for SW, 10% for
70-85 cm^(-1) of LW, and 20% for 60-70 cm^(-1) of LW; and the absolute
uncertainty is estimated to be +35/-55% for SW, +35/-55% for 70-85 cm^(-1) of
LW, and +40/-60% for 60-70 cm^(-1) of LW. These values are confirmed by
comparison with theoretical models and previous observations by the ISO/LWS.Comment: 22 pages, 10 figure
Calibration and Performance of the AKARI Far-Infrared Surveyor (FIS) -- Slow-Scan Observation Mode for Point Sources
We present the characterization and calibration of the Slow-Scan observation
mode of the Far-Infrared Surveyor (FIS) onboard the AKARI satellite. The FIS,
one of the two focal-plane instruments on AKARI, has four photometric bands
between 50--180 um with two types of Ge:Ga array detectors. In addition to the
All-Sky Survey, FIS has also taken detailed far-infrared images of selected
targets by using the Slow-Scan mode. The sensitivity of the Slow-Scan mode is
one to two orders of magnitude better than that of the All-Sky Survey, because
the exposure time on a targeted source is much longer. The point spread
functions (PSFs) were obtained by observing several bright point-like objects
such as asteroids, stars, and galaxies. The derived full widths at the half
maximum (FWHMs) are ~30'' for the two shorter wavelength bands and ~40'' for
the two longer wavelength bands, being consistent with those expected by the
optical simulation, although a certain amount of excess is seen in the tails of
the PSFs. The flux calibration has been performed by the observations of
well-established photometric calibration standards (asteroids and stars) in a
wide range of fluxes. After establishing the method of aperture photometry, the
photometric accuracy for point-sources is better than +-15% in all of the bands
expect for the longest wavelength.Comment: 25 pages, 7 figures, accepted publication in PAS
The Far-Infrared Surveyor (FIS) for AKARI
The Far-Infrared Surveyor (FIS) is one of two focal plane instruments on the
AKARI satellite. FIS has four photometric bands at 65, 90, 140, and 160 um, and
uses two kinds of array detectors. The FIS arrays and optics are designed to
sweep the sky with high spatial resolution and redundancy. The actual scan
width is more than eight arcmin, and the pixel pitch is matches the diffraction
limit of the telescope. Derived point spread functions (PSFs) from observations
of asteroids are similar to the optical model. Significant excesses, however,
are clearly seen around tails of the PSFs, whose contributions are about 30% of
the total power. All FIS functions are operating well in orbit, and its
performance meets the laboratory characterizations, except for the two longer
wavelength bands, which are not performing as well as characterized.
Furthermore, the FIS has a spectroscopic capability using a Fourier transform
spectrometer (FTS). Because the FTS takes advantage of the optics and detectors
of the photometer, it can simultaneously make a spectral map. This paper
summarizes the in-flight technical and operational performance of the FIS.Comment: 23 pages, 10 figures, and 2 tables. Accepted for publication in the
AKARI special issue of the Publications of the Astronomical Society of Japa
2017~2019年度 関西大学研究拠点形成支援経費研究成果報告書
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キンチ ジシン ハケイ オ モチイタ チュウゴク チホウ ノ チカク オヨビ サイジョウブ マントル ノ ショウサイナ Sハ ハンシャ コウゾウ ノ スイテイ
京都大学0048新制・課程博士博士(理学)甲第13599号理博第3257号新制||理||1481(附属図書館)UT51-2008-C517京都大学大学院理学研究科地球惑星科学専攻(主査)准教授 西上 欽也, 教授 平原 和朗, 教授 伊藤 潔学位規則第4条第1項該当Doctor of ScienceKyoto UniversityDA
Low levels of serum n-3 polyunsaturated fatty acids are associated with worse heart failure-free survival in patients after acute myocardial infarction
Masahiko Hara, Yasuhiko Sakata, Daisaku Nakatani, Shinichiro Suna, Masaya Usami, Sen Matsumoto, Toshimitsu Hamasaki, Yasuji Doi, Masami Nishino, Hiroshi Sato, Tetsuhisa Kitamura, Shinsuke Nanto, Masatsugu Hori, Issei Komuro, for the Osaka Acute Coronary Insufficiency Study (OACIS) Investigators, Low Levels of Serum n-3 Polyunsaturated Fatty Acids Are Associated With Worse Heart Failure-Free Survival in Patients After Acute Myocardial Infarction, Circulation Journal, 2013, Volume 77, Issue 1, Pages 153-162, Released December 25, 2012, [Advance publication] Released October 06, 2012, Online ISSN 1347-4820, Print ISSN 1346-9843, https://doi.org/10.1253/circj.CJ-12-0875, https://www.jstage.jst.go.jp/article/circj/77/1/77_CJ-12-0875/_article/-char/e
Effectiveness and safety of nivolumab in patients with head and neck cancer in Japanese real-world clinical practice : a multicenter retrospective clinical study
Background To fill the data gap between clinical trials and real-world settings, this study assessed the overall effectiveness and safety of nivolumab in patients with head and neck cancer (HNC) during Japanese real-world clinical practice. Methods This was a multicenter, retrospective study in Japanese patients with recurrent or metastatic HNC who received nivolumab for the first time between July and December 2017. Data on the clinical use, effectiveness, and safety of nivolumab were extracted from patient medical records. Results Overall, 256 patients were enrolled in this study. The median duration of nivolumab treatment was 72.5 days, with patients receiving a median of 6.0 (range 1-27) doses. Median overall survival (OS) was 9.5 (95% confidence interval [CI] 8.2-12.0) months and the estimated 12-month OS rate was 43.2%. The objective response rate (ORR) was 15.7% overall and 21.1%, 7.1%, and 13.6% in patients with primary nasopharynx, maxillary sinus, and salivary gland tumors, respectively, who had been excluded from CheckMate 141. Grade >= 3 immune-related adverse events occurred in 5.9% of patients. No new safety signals were identified compared with adverse events noted in CheckMate 141. Conclusions The effectiveness and safety of nivolumab in real-world clinical practice are consistent with data from the CheckMate 141 clinical trial. Therapeutic response was also observed in the groups of patients excluded from CheckMate 141