190 research outputs found
Anomalous radiative transitions
Anomalous transitions involving photons derived by many-body interaction of
the form, , in the standard model are studied. This
does not affect the equation of motion in the bulk, but makes wave functions
modified, and causes the unusual transition characterized by the
time-independent probability. In the transition probability at a time-interval
expressed generally in the form , now with . The diffractive term has the origin in the overlap of waves
of the initial and final states, and reveals the characteristics of waves. In
particular, the processes of the neutrino-photon interaction ordinarily
forbidden by Landau-Yang's theorem () manifests itself through the
boundary interaction. The new term leads to physical processes over a wide
energy range to have finite probabilities. New methods of detecting neutrinos
using laser are proposed that are based on this difractive term, which enhance
the detectability of neutrinos by many orders of magnitude.Comment: 47 pages, 5 figures, 1 table, typos correcte
Transphosphatidylation by GIPC-PLD
Glycosylinositol phosphoceramide (GIPC) is the most abundant sphingolipid in plants and fungi. Recently, we detected GIPC-specific phospholipase D (GIPC-PLD) activity in plants. Here, we found that GIPC-PLD activity in young cabbage leaves catalyzes transphosphatidylation. The available alcohol for this reaction is a primary alcohol with a chain length below C4. Neither secondary alcohol, tertiary alcohol, choline, serine nor glycerol serves as an acceptor for transphosphatidylation of GIPC-PLD. We also found that cabbage GIPC-PLD prefers GIPC containing two sugars. Neither inositol phosphoceramide, mannosylinositol phosphoceramide nor GIPC with three sugar chains served as substrate. GIPC-PLD will become a useful catalyst for modification of polar head group of sphingophospholipid
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The Arabidopsis thaliana nucleotide sugar transporter GONST2 is a functional homolog of GONST1.
Glycosylinositolphosphorylceramides (GIPCs) are the predominant lipid in the outer leaflet of the plasma membrane. Characterized GIPC glycosylation mutants have severe or lethal plant phenotypes. However, the function of the glycosylation is unclear. Previously, we characterized Arabidopsis thaliana GONST1 and showed that it was a nucleotide sugar transporter which provides GDP-mannose for GIPC glycosylation. gonst1 has a severe growth phenotype, as well as a constitutive defense response. Here, we characterize a mutant in GONST1's closest homolog, GONST2. The gonst2-1 allele has a minor change to GIPC headgroup glycosylation. Like other reported GIPC glycosylation mutants, gonst1-1gonst2-1 has reduced cellulose, a cell wall polymer that is synthesized at the plasma membrane. The gonst2-1 allele has increased resistance to a biotrophic pathogen Golovinomyces orontii but not the necrotrophic pathogen Botrytis cinerea. Expression of GONST2 under the GONST1 promoter can rescue the gonst1 phenotype, indicating that GONST2 has a similar function to GONST1 in providing GDP-D-Man for GIPC mannosylation
Synthesis and Functional Evaluation of Sulfides : Application of Solid Lubricant and Thermoelectric Material
Sufides as MoS2 are known as solid lubricants. These materials are also known as thermoelectric materials. However, there is no material satisfying both functions at the same time. In this study, sulfides powders such as Cu2S (chalcocite), TiS2, SnS, Cu5FeS4 (bornite) were synthesized under vacuum condition. Some specimens of sintered sulfides were evaluated by friction tester and their lubricity. As a result it was found that SnS had indicated better friction properties. Other specimens were evaluated in terms of Seebeck coefficients, which is one of the thermoelectric properties. Experimental results of the Seebeck coefficients were compared with simulation results. For thermoelectric properties, the Seebeck coefficient of Cu2S had matched with experiments and simulation. Totally, Cu2S (chalcocite) and SnS has superior properties both, as solid lubricant as well as thermoelectric material.This is a product of research which was financially supported in part by the Kansai University Subsidy for Supporting Young Scholars, 2016 – \u27Study on sulfide synthesis of superior solid lubricity and thermoelectric properties\u2
TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella
Cilia/flagella are assembled and maintained by the process of intraflagellar transport (IFT), a highly conserved mechanism involving more than 20 IFT proteins. However, the functions of individual IFT proteins are mostly unclear. To help address this issue, we focused on a putative IFT protein TTC26/DYF13. Using live imaging and biochemical approaches we show that TTC26/DYF13 is an IFT complex B protein in mammalian cells and Chlamydomonas reinhardtii. Knockdown of TTC26/DYF13 in zebrafish embryos or mutation of TTC26/DYF13 in C. reinhardtii, produced short cilia with abnormal motility. Surprisingly, IFT particle assembly and speed were normal in dyf13 mutant flagella, unlike in other IFT complex B mutants. Proteomic and biochemical analyses indicated a particular set of proteins involved in motility was specifically depleted in the dyf13 mutant. These results support the concept that different IFT proteins are responsible for different cargo subsets, providing a possible explanation for the complexity of the IFT machinery. DOI: http://dx.doi.org/10.7554/eLife.01566.00
18. asırda "Hırkai şerif" ziyareti
Taha Toros Arşivi, Dosya No: 120-Saraylar. Not: Gazetenin "Tarihten Sahifeler" köşesinde yayımlanmıştır.İstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN/0033
Risk factors for severity of colonic diverticular hemorrhage
Background/AimsColonic diverticular hemorrhage (DH) was a rare disease until the 1990s, and its incidence has increased rapidly since 2000 in Japan. In recent years, colonic DH has been the most frequent cause of lower gastrointestinal bleeding (LGIB). Nearly all cases of DH are mild, with the bleeding often stopping spontaneously. Some cases, however, require surgery or arterial embolization. In this study, using a cohort at Fukuoka University Chikushi Hospital, we investigated factors associated with severe colonic DH.MethodsAmong patients with LGIB who underwent colonoscopy at our hospital between 1995 and 2013, DH was identified in 273 patients. Among them, 62 patients (22.7%) were defined as having severe colonic DH according to recurrence of bleeding in a short period, and/or the necessity of transfusion, arterial embolization, or surgery. We then evaluated risk factors for severe DH among DH patients in this retrospective cohort.ResultsAmong the 273 patients with DH, use of non-steroidal anti-inflammatory drugs (NSAIDs) (odds ratio [OR], 2.801; 95% confidence interval [CI], 1.164–6.742), Charlson Risk Index (CRI) ≥2 (OR, 3.336; 95% CI, 1.154–7.353), right-sided colonic DH (OR, 3.873; 95% CI, 1.554–9.653), and symptoms of cerebral hypoperfusion (such as light-headedness, dizziness, or syncope) (OR, 2.926; 95% CI, 1.310–6.535) showed an increased risk of severe DH even after controlling for other factors.ConclusionsSevere DH occurred in 23% of DH patients, and NSAID use, CRI ≥2, right-sided colonic DH, and symptoms of cerebral hypoperfusion are suggested to be predictors of severe DH
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