134 research outputs found
Analisis Keputusan Pembelian Konsumen Terhadap Produk Mie Sedaap Pada Pasar Modern Di Surakarta
Pasar modern merupakan salah satu tempat perbelanjaan yang saat ini diminati masyarakat. Berbagai cara di lakukan pengelola pasar modern untuk memikat hati para konsumen. Beberapa faktor yang mempengaruhi keputusan pembelian konsumen yang belanja di pasar modern adalah harga, kualitas produk, keamanan parkir dan promosi. Dari beberapa faktor tersebut harus dipertimbangkan oleh pengelola agar dapat meningkatkan volume penjualan. Perumusan masalah dalam penelitian adalah menganalisis pengaruh harga, kualitas produk, keamanan parkir, dan promosi terhadap keputusan pembelian mie sedap di pasar modern yang berada di surakarta, faktor manakah di antara harga, kualitas produk, keamanan parkir, dan promosi yang berpengaruh terhadap
keputusan pembelian mie sedap pada pasar modern di surakarta. Dalam penelitian ini alat analisis yang digunakan adalah uji validitas, uji reliabilitas, uji asumsi klasik, dan uji hipotesis yang meliputi uji regresi linier
berganda, uji t, uji F dan koefisian determinasi (R2). Dari hasil analisis tersebut dapat disimpulkan bahwa hanya variabel kualitas produk yang berpengaruh positif
dan signifikan terhadap keputusan pembelian mie sedaap pada pasar modern di surakarta dengan nilai uji t sebesar 2,910. Sedangakan variabel yang tidak signifikan adalah harga, keamanan parkir, dan promosi, hal itu di karenakan nilai
uji t lebih kecil dari pada t tabel
Pengaruh Kualitas Pelayanan, Kepercayaan Dan Religious Commitmen Terhadap Loyalitas Pelanggan Pada Bank Bni Syariah Surakarta
This study aims to analyze the influence of service quality, trust and religious commitment to customer loyalty at Bni Syariah Surakarta Bank. The sample in this study amounted to 98 employees of Bni Syariah Surakarta Bank using a questionnaire for data collection. The sampling technique is a non probability sampling method. Data analysis techniques using multiple linear regression analysis. The results of this study indicate that: Service quality, trust and commitment religiosity have a significant influence on customer loyalt
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Abstract:
Rubella, measles, and varicella-zoster can produce exanthematous infections in pregnant women, associated to greater risk or complications, including miscarriage, premature labor, neonatal diseases, and low birth-weight, among others. However, these infections are preventable by means of existing safe and effective vaccines.
We intended to determine the prevalence of specific antibodies for rubella, measles and varicella-zoster viruses in a population of pregnant women who attended a private medical center in Córdoba city (Argentina).
Retrospective observational study of 826 serum samples from pregnant women aged 18-42 years, collected at the Virology Laboratory Clínica Universitaria Reina Fabiola, from January 1 to December 31, 2020. The population was divided into 5 groups according to age (1 group every 5 years). For determination of antibodies, we used automated Elisa assay (bioMérieux) according to the manufacturer´s instructions. Positive values were defined according to the cut-off points established by the manufacturer for each assay: rubella IgG: ≥15 UI/ml, measles IgG index: ≥0.7 and varicella-zoster IgG index: ≥0.90. The proportion of individuals with immunity against the viruses was compared using Chi square test with 95% CI (p<0.05).
Detected prevalence values were rubella IgG: 95.52%, measles IgG: 79.97%, and varicella-zoster IgG: 94.39%. When comparing the global prevalence of rubella and varicella-zoster with respect to global prevalence of measles (p <0.0001), we observed a higher prevalence of anti-rubella and anti-varicella-zoster antibodies in pregnant women and a significantly lower prevalence against measles virus (global susceptibility: 20.03%).
For this reason, it would be advisable to perform serological control of rubella, measles and varicella before conception in order to establish a new preventive strategy to reduce the risk of these infections in newborns and pregnant women of our community.Resumen:
Los virus rubéola, varicela-zóster y sarampión en la mujer embarazada pueden provocar infecciones exantemáticas asociadas a un mayor riesgo de complicaciones que incluyen aborto, parto prematuro, enfermedad neonatal, bajo peso al nacer, entre otros. Estos virus son prevenibles, ya que existe una vacuna segura y eficaz para cada caso.
Determinar la prevalencia de anticuerpos específicos para virus rubéola, varicela-zóster y sarampión en una población de mujeres embarazadas que concurrieron a un centro medico privado de la ciudad de Córdoba.
Estudio retrospectivo observacional de muestras de suero de mujeres embarazadas de 18 a 42 años de edad, recolectadas en el laboratorio de Virologia de la Clinica Universitaria Reina Fabiola, desde el 1 de enero al 31 de diciembre del 2020 . Se analizaron 826 sueros. Se dividió la población en 5 grupos cada 5 años de edad. Para la determinación de los diferentes anticuerpos, se utilizó un ensayo de ELISA automatizado (bioMerieux) siguiendo las indicaciones del fabricante. Se consideraron valores positivos según los cortes establecidos por el fabricante para cada ensayo: para IgG rubéola ≥ 15 UI/ml, para IgG sarampión índice ≥ 0.7 y para IgG varicela índice ≥ 0.90. Se comparó la proporción de individuos con inmunidad frente a estos virus utilizando el test de Chi Cuadrado con un 95% de nivel de confianza (p<0,05).
Las prevalencias observadas fueron: para IgG rubeola del 95.52 %, para IgG varicela-zóster del 94.39 % y para IgG sarampión del 79.97. Al comparar las prevalencias globales de los anticuerpos estudiados, se observó diferencia significativa entre las prevalencias globales de rubéola y varicela-zóster con respecto a la prevalencia global de sarampión (p < 0.0001).
Se observó una elevada prevalencia de anticuerpos anti virus rubéola y varicela-zoster en embarazadas, mientras que se encontró una prevalencia significativamente más baja, con una susceptibilidad global del 20,03% frente al virus sarampión. Por lo cual, sería recomendable realizar el control serológico de rubéola, sarampión y varicela en la etapa preconcepcional, con el fin de establecer una nueva estrategia preventiva para reducir el riesgo de estas infecciones en los recién nacidos y en mujeres embarazadas de nuestra comunidad.
Increased Hepatitis E Virus Seroprevalence Correlates with Lower CD4+Cell Counts in HIV-Infected Persons in Argentina
Hepatitis E virus (HEV) is a single-stranded RNA virus that can cause hepatitis in an epidemic fashion. HEV usually causes asymptomatic or limited acute infections in immunocompetent individuals, whereas in immunosuppressed individuals such as transplant recipients, HEV can cause chronic infections. The risks and outcomes of HEV co-infection in patients infected with human immunodeficiency virus (HIV) are poorly characterized. We used a third generation immunoassay to measure serum IgG antibodies specific for HEV in 204 HIV-infected individuals from Argentina and a control group of 433 HIV-negative individuals. We found 15 of 204 (7.3%, 95% CI 3.74-10.96%) individuals in the HIV-positive group to have positive HEV IgG levels suggestive of previous infection, compared to 19 of 433 (4.4%, 95% CI 2.5-6.3%) individuals in the HIV-negative control group (p = 0.12). Among HIV-positive individuals, those with HEV seropositivity had lower CD4 counts compared to those that were HEV seronegative (average CD4 count of 234 vs 422 mm(3), p = 0.01), indicating that patients with lower CD4 counts were more likely to be HEV IgG positive. Moreover, HEV seropositivity in patients with CD4 counts <200 mm(3) was 16%, compared to 4.5% in those with CD4 counts >200 mm(3) (p = 0.012). We found a positive PCR result for HEV in one individual. Our study found that increased seroprevalence of HEV IgG correlated with lower CD4 counts in HIV-infected patients in Argentina
ANALISIS EFISIENSI JUMLAH PEGAWAI PAJAK DAN ANGGARAN TERHADAP KINERJA KANTOR PELAYANAN PAJAK PRATAMA DI KANWIL DIREKTORAT JENDERAL PAJAK JAWA TENGAH II
The study aims to analyze the efficiency performance of the Pratama Tax Office in the Central Java Regional Tax Office II. The data uses secondary data in 2015-2018 at the KPP Pratama in the Regional Office of the Directorate General of Tax, Central Java II. The analysis technique uses the WDEA application. The results of the analysis test produced are the results of valid and reliable efficiency. From the results of the analysis it was concluded that the level of efficiency in several Primary Tax Service Offices varies depending on the year and the input data used. From the efficiency value it can be concluded that the efficiency value obtained becomes more efficient with the presence of a tax bailiff. With this research it is hoped that it can be used to improve efficiency in each Primary Tax Service Office either by minimizing resources or increasing output produced
Keywords: Efficiency, Primary Tax Office, Ta
Analisis Efisiensi Organisasi Pengelola Zakat Nasional dengan Pendekatan Data Envelopment Analysis (DEA)
The aim of this paper is to analysis the efficiency of National Zakat Institutions during period of 2014 to 2017. Using Data Envelopment Analysis (DEA) technique with production and intermediation approach. This research is descriptive study with quantitative method. The subject of this study is National Zakat Institutions with purposive sampling technique. From 26 OPZs that have been legalized by the goverment and recommended by Dirjen Pajak, eight OPZs are chosen according to the sample criteria, namely Badan Amil Zakat Nasional, Rumah Zakat, Daarut Tauhid, Dompet Dhuafa Republika, Yatim Mandiri Surabaya, Dewan Dakwah Islamiyah, Baitul Maal Muamalat, and Baitul Maal Hidayatullah. This study uses secondary data in the form of annual financial reports from 2014 to 2017 period. The data in this study is collected by documentation method, and the analysis tool use Data Envelopment Analysis (DEA) with production and intermediation approachs and Constant Return to Scale (CRS) assumption. The results show that the National Zakat Institutions efficiency level is fluctuated during 2014 to 2017. Futhermore, the results also show the National Zakat Institutions with the highest efficiency score during 2014 to 2017 based on efficiency measurement of production approach is Dompet Dhaufa Republika, whereas the lowest level of efficiency is Baitul Maal Muamalat. The result of measurement with intermediate approach during 2014-2017 shows that 6 from 7 National Zakat Institutions are 100% efficient, only Dompet Dhuafa Republika which is inefficient in 2015
Strategi Peningkatan Kualitas Pelayanan Rumah Sakit Berdasarkan Indikator Mutu Keselamatan Pasien : Studi Pada Rumah Sakit Umum (Rsu) Hidayah Boyolali
This study aims to analyze the strategies for improving the quality of hospital services through the application of patient safety indicators at the Boyolali Hidayah General Hospital. This study focuses on analyzing two indicators of patient safety, namely: aspects of adherence to the identification of inpatients and aspects of compliance with effective communication. The research method used in this study is a quantitative research method with a descriptive approach. The results of this study indicate that the aspect of compliance of medical officers to the procedure of identification of inpatients is included in good condition, this can be seen from the results of an audit of patient identification compliance stating that the Boyolali Hidayah General Hospital has achieved compliance rates above 85% in August 2017 has reached 100% compliance rate in December 2017. While the level of compliance of the Hidayah Boyolali General Hospital towards effective communication procedures is included in the good category, this can be seen from the compliance rate which reached 80% in October 2017 and reached 86% in December 2017. Alternative strategies include: monitoring and evaluation of SPO patient identification, periodic socialization of effective communication SPO, periodic socialization of the use of identity bracelet SPO from medical officers to patients, periodic audits of compliance with SPO effective communication, periodic socialization of compliance with SPO identification of patients
Pengaruh Gaya Kepemimpinan, Kompensasi, dan Kepuasan Kerja Terhadap Kinerja Pegawai ( Studi Empris pada Sekolah Menengah Kejuruan (SMK) Swasta Kota Salatiga )
The aims of the research is to analyze the effect of Leadership style, Compensation and job satisfaction on employee performance. The used data in this research is the primary data which are collected from 91 respondents on the questionaires given to the officials of Private Vocational High School (SMK) in Salatiga by sampling quote methods. The tool that used in this researh is multilinear regresion. Based on the instrument test shown that all variables are valid and reliable. The clasical assumption result indicate that the data normally distribute. Moreover there are no multicolinearity and heteroschedasity. Based on data analysis, founded that leadrship style and job satisfaction significantly affect on the officials performance
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer
Transcriptional reactivation of telomerase catalytic subunit (TERT) is a frequent hallmark of cancer, occurring in 90% of human malignancies. However, specific mechanisms driving TERT reactivation remain obscure for many tumor types and in particular gastric cancer (GC), a leading cause of global cancer mortality. Here, through comprehensive genomic and epigenomic analysis of primary GCs and GC cell lines, we identified the transcription factor early B cell factor 1 (EBF1) as a TERT transcriptional repressor and inactivation of EBF1 function as a major cause of TERT upregulation. Abolishment of EBF1 function occurs through 3 distinct (epi)genomic mechanisms. First, EBF1 is epigenetically silenced via DNA methyltransferase, polycomb-repressive complex 2 (PRC2), and histone deacetylase activity in GCs. Second, recurrent, somatic, and heterozygous EBF1 DNA–binding domain mutations result in the production of dominant-negative EBF1 isoforms. Third, more rarely, genomic deletions and rearrangements proximal to the TERT promoter remobilize or abolish EBF1-binding sites, derepressing TERT and leading to high TERT expression. EBF1 is also functionally required for various malignant phenotypes in vitro and in vivo, highlighting its importance for GC development. These results indicate that multimodal genomic and epigenomic alterations underpin TERT reactivation in GC, converging on transcriptional repressors such as EBF1
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