EVALUATING ENVIRONMENTAL EDUCATION OF TEXTILE STUDENTS AND THEIR ATTITUDES TOWARD ENVIRONMENTAL DEGRADATION

Bangladesh has been experiencing serious environmental degradation for last few years specially for textile and apparel industries. The objective of this research is to evaluate the level of environmental education of outgoing textile undergraduate students and their perception about the environmental degradation. A questionnaire was developed and administered to textile outgoing and 1st semester students to assess their environmental concern, knowledge and responsibility. Two sample mean test was applied to differentiate the level of understanding of these two groups of students. Binary logistic regression was used to identify the most potential source to build up the consciousness among the students about pollution. The multiple regression analysis was done to assess the comparative role of knowledge and concern for showing the responsibility towards the environment. The result indicated that the level of understanding of outgoing students on environmental sustainability is not up to the mark, there is potential for further enhancing environmental learning. It revealed that responsibility toward the environment is directly proportional to knowledge and concern. Findings also suggested that the university and the electronic media have a significant role to increase the environmental awareness among the students

Mathematical Logic Establishment for Automated Trash Controlling in Carding Machine

In this paper, it is intended to establish a mathematical logic for the purpose of removal of trash in an automatic way and removal of trash will refer to the cleaning process of carding machine. But the selection of degree of cleaning has to be optimum considering other process factors like fiber loss, fiber rupturing, neps generation etc. Higher degree of cleaning causes higher degree of fiber loss. And in spinning mill, fiber loss means money loss as raw cotton purchasing cost consumes 50% to 60% of total manufacturing cost of yarn in terms of Bangladesh. Alongside, fiber loss is affected the cleaning system because the system is designed for fiber cleaning, not for fiber loss. So, it is necessary to measure the performance of the system. For this purpose, we have chosen two terms, ‘Cleaning Efficiency (C.E.)’ to measure the degree of cleaning & ‘Effective Cleaning (E.C.)’ to measure the performance of the system. In this paper, it is intended to describe a relationship between these two terms, graphical expression of the individuals, a way to calculate the force applied by mechanical means and the force required to clean. The ultimate result of this project is to find the relationship between the surface speed of taker-in and the trash weight of output material

Tyrosinase inhibition: conformational analysis based studies on molecular dynamics calculations of bipiperidine based inhibitors.

Two series of variably N-substituted biperidines were synthesized by condensing various acid chlorides, alkyl halides and anhydrides with 1,4-bipiperidine. The new compounds were tested as tyrosinase inhibitors and a structure-activity relationship (SAR) study was carried out. Potent inhibition was observed in the case of the 4'-methylbenzyl substitution on this atom (IC50 = 1.72 microM) with this compound being a lead for future drug design. Additionally, calculations of the important QSAR molecular descriptors were done on the biperidine analogues after their 2 ps molecular dynamics (MD) simulations using molecular mechanics force field (MMFF) approaches. Using MD simulations potential and total energies were calculated for the energy minimized models of bipiperidine and the most active analogs 2, 3, 4, 6, 8 and 10

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021.MethodsWe estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous system combined.FindingsGlobally, the 37 conditions affecting the nervous system were collectively ranked as the leading group cause of DALYs in 2021 (443 million, 95% UI 378–521), affecting 3·40 billion (3·20–3·62) individuals (43·1%, 40·5–45·9 of the global population); global DALY counts attributed to these conditions increased by 18·2% (8·7–26·7) between 1990 and 2021. Age-standardised rates of deaths per 100 000 people attributed to these conditions decreased from 1990 to 2021 by 33·6% (27·6–38·8), and age-standardised rates of DALYs attributed to these conditions decreased by 27·0% (21·5–32·4). Age-standardised prevalence was almost stable, with a change of 1·5% (0·7–2·4). The ten conditions with the highest age-standardised DALYs in 2021 were stroke, neonatal encephalopathy, migraine, Alzheimer's disease and other dementias, diabetic neuropathy, meningitis, epilepsy, neurological complications due to preterm birth, autism spectrum disorder, and nervous system cancer.InterpretationAs the leading cause of overall disease burden in the world, with increasing global DALY counts, effective prevention, treatment, and rehabilitation strategies for disorders affecting the nervous system are needed

Numerical Investigation of Heat Transfer on Unsteady Hiemenz Cu-Water and Ag-Water Nanofluid Flow over a Porous Wedge Due to Solar Radiation

Nanoparticles are generally used to scatter and absorb solar radiations in nanofluid-based direct solar receivers to efficiently transport and store the heat. However, solar energy absorption in nanofluid can be enhanced by using differential materials and tuning nanofluid parameter. In this regard, theoretical investigations of unsteady homogeneous Hiemenz flow of an incompressible nanofluid having copper and silver nanoparticles over a porous wedge is carried out by using optimal homotopy asymptotic method (OHAM). Hence, a semi-analytical solver is applied to the transformed system to study the significance of magnetic field along with Prandtl number. In this work, impacts of conductive radiations, heat sink/source, unsteadiness, and flow parameters have been investigated for velocity and temperature profiles of copper and silver nanoparticles-based nanofluid. The effects of magnetic strength, volume fraction of nanoparticles, thermal conductivity, and flow parameters have also been studied on the considered nanofluids

Potent tyrosinase inhibitors from Trifolium balansae

Trifolium balansae ( Leguminosae) yielded a phytylester, phytyl-1-hexanoate, three steroids, stigmast-5-ene-3 beta,26-diol, stigmast-5-ene-3-ol and campesterol, and an alcohol, pentacosanol which were reported for the first time from T. balansae. The structures of the isolates were determined by 1D and 2DNMR techniques and MS spectroscopy. Compounds 1 - 5 were tested for their enzyme tyrosinase activity. While compounds 1 and 5 did not show any inhibition against the enzyme tyrosinase, compounds 2, 3, and 4 exhibited potent inhibition against tyrosinase. Highly potent ( IC50 = 2.39 mu M) inhibition was found by compound 2, when compared with the standard tyrosinase inhibitors Kojic acid and L-mimosine

Dynamical Study of Fokker-Planck Equations by Using Optimal Homotopy Asymptotic Method

In this article, Optimal Homotopy Asymptotic Method (OHAM) is used to approximate results of time-fractional order Fokker-Planck equations. In this work, 3rd order results obtained through OHAM are compared with the exact solutions. It was observed that results from OHAM have better convergence rate for time-fractional order Fokker-Planck equations. The solutions are plotted and the relative errors are tabulated

Beta-arrestins in the treatment of heart failure related to hypertension: a comprehensive review

Heart failure (HF) is a complicated clinical syndrome that is considered an increasingly frequent reason for hospitalization, characterized by a complex therapeutic regimen, reduced quality of life, and high morbidity. Long-standing hypertension ultimately paves the way for HF. Recently, there have been improvements in the treatment of hypertension and overall management not limited to only conventional medications, but several novel pathways and their pharmacological alteration are also conducive to the treatment of hypertension. Beta-arrestin (β-arrestin), a protein responsible for beta-adrenergic receptors’ (β-AR) functioning and trafficking, has recently been discovered as a potential regulator in hypertension. β-arrestin isoforms, namely β-arrestin1 and β-arrestin2, mainly regulate cardiac function. However, there have been some controversies regarding the function of the two β-arrestins in hypertension regarding HF. In the present review, we try to figure out the paradox between the roles of two isoforms of β-arrestin in the treatment of HF