2,608 research outputs found
Locking device for turbine rotor blades Patent
Locking device for retaining turbine rotor blades on turbine whee
Anodically polarized nickel electrodes in DMSO or DMF solutions of pseudohalide ions: IR spectroelectrochemical studies
A novel subtractively normalized interfacial Fourier transform infrared spectroscopic (SNIFTIRS) investigation of anodically polarized nickel electrodes in pseudohalide-containing DMF or DMSO solutions (i.e. OCN⁻, SCN⁻, SeCN⁻), in supporting electrolyte, tetrabutylammonium perchlorate (TBAP), is presented. In general, the data showed that nickel demonstrated irreversible anodic dissolution in all solutions studied at very high values of the applied potential, > +500 mV (AgCl/Ag). The predominant speciation of nickel in these systems was as complex ions consisting of Ni²⁺ ion complexed to pseudohalide ions and solvent molecules. Insoluble films and dissolved CO₂ were also detected, though mostly in the Ni/OCN⁻ systems studied. Ni(II)/pseudohalide complex ion species detected were modeled using solutions containing Ni²⁺ ion mixed with pseudohalide ion in different mole ratios. In general, the Ni/OCN⁻ electrochemical system behaved differently relative to those of Ni/SCN⁻ and Ni/SeCN⁻ due to the difference in colors observed in cell solutions after SNIFTIRS experiments which was mirrored in the model solutions. Ni(II)-cyanate species had a different, coordination geometry and gave a characteristic bright blue color due possibly to Ni(NCO)₄²⁻ ion while Ni(II) thiocyanate and selenocyanate complex ion species had octahedral coordination geometries containing solvent and one coordinated pseudohalide ion and formed greeny yellow solutions
Isostatic compression process converts polyaromatics into structural material
Isostatic compression process compacts certain powdered aromatic polymers into homogeneous materials that can be machined to form useful components, such as bearings. It provides for complete removal of air in the interstitial spaces surrounding the granules of the powdered polymer before the powder is subjected to isostatic compression
Modelling and optimisation of the operation of a radiant warmer
This paper presents numerical calculations of the temperature field obtained for the case of a neonate placed under a radiant warmer. The results of the simulations show a very non-uniform temperature distribution on the skin of the neonate, which may cause increased evaporation leading to severe dehydration. For this reason, we propose some modifications on the geometry and operation of the radiant warmer, in order to make the temperature distribution more uniform and prevent the high temperature gradients observed on the surface of the neonate. It is concluded that placing a high conductivity blanket over the neonate and introducing additional screens along the side of the mattress, thus recovering the radiation heat escaping through the side boundaries, helped providing more uniform temperature fields.The European Union for the Marie Curie Fellowship grant awarded to the Centre for CFD, University of Leeds
Synaptic Protection in the Brain of WldS Mice Occurs Independently of Age but Is Sensitive to Gene-Dose
Disruption of synaptic connectivity is a significant early event in many neurodegenerative conditions affecting the aging CNS, including Alzheimer's disease and Parkinson's disease. Therapeutic approaches that protect synapses from degeneration in the aging brain offer the potential to slow or halt the progression of such conditions. A range of animal models expressing the slow Wallerian Degeneration (Wld(S)) gene show robust neuroprotection of synapses and axons from a wide variety of traumatic and genetic neurodegenerative stimuli in both the central and peripheral nervous systems, raising that possibility that Wld(S) may be useful as a neuroprotective agent in diseases with synaptic pathology. However, previous studies of neuromuscular junctions revealed significant negative effects of increasing age and positive effects of gene-dose on Wld(S)-mediated synaptic protection in the peripheral nervous system, raising doubts as to whether Wld(S) is capable of directly conferring synapse protection in the aging brain.We examined the influence of age and gene-dose on synaptic protection in the brain of mice expressing the Wld(S) gene using an established cortical lesion model to induce synaptic degeneration in the striatum. Synaptic protection was found to be sensitive to Wld(S) gene-dose, with heterozygous Wld(S) mice showing approximately half the level of protection observed in homozygous Wld(S) mice. Increasing age had no influence on levels of synaptic protection. In contrast to previous findings in the periphery, synapses in the brain of old Wld(S) mice were just as strongly protected as those in young mice.Our study demonstrates that Wld(S)-mediated synaptic protection in the CNS occurs independently of age, but is sensitive to gene dose. This suggests that the Wld(S) gene, and in particular its downstream endogenous effector pathways, may be potentially useful therapeutic agents for conferring synaptic protection in the aging brain
Mitigating Gender Bias in Machine Learning Data Sets
Artificial Intelligence has the capacity to amplify and perpetuate societal
biases and presents profound ethical implications for society. Gender bias has
been identified in the context of employment advertising and recruitment tools,
due to their reliance on underlying language processing and recommendation
algorithms. Attempts to address such issues have involved testing learned
associations, integrating concepts of fairness to machine learning and
performing more rigorous analysis of training data. Mitigating bias when
algorithms are trained on textual data is particularly challenging given the
complex way gender ideology is embedded in language. This paper proposes a
framework for the identification of gender bias in training data for machine
learning.The work draws upon gender theory and sociolinguistics to
systematically indicate levels of bias in textual training data and associated
neural word embedding models, thus highlighting pathways for both removing bias
from training data and critically assessing its impact.Comment: 10 pages, 5 figures, 5 Tables, Presented as Bias2020 workshop (as
part of the ECIR Conference) - http://bias.disim.univaq.i
Outside interference or Hong Kong embracing its unique identity? : The Chinese Universities Shakespeare Festival
Ongoing clashes between Hong Kong citizens and its government have foregrounded questions about outside interference in Hong Kong’s politics (largely from the government and media of People’s Public of China), as well as debate about what institutions in Hong Kong are neo-colonial, heavily inflected with nostalgia for British colonialism, or in the process of being ‘colonised’ by the People’s Republic of China. This article looks at Shakespeare in Hong Kong (and, to some extent, greater Chinese) theatre and education as one of those contested institutions, using the particular case of the now-defunct Chinese Universities Shakespeare Festival. The author probes their initial, surface impression of the festival as a simple outpouring of colonial sentiment and impulse, using its sizeable archives to realise a reading of the institution that highlights the complexities of international and intra-regional politics, culture and identity in Hong Kong and greater China. It builds on the Hong Kong literary critic Michael Ingham’s call for attention to Hong Kong’s quest – sometimes overt (as in the demonstrations of 2019), sometimes implicit (in the body of literature Ingham explores in his cultural and literary history) – for a unique, post-colonial identity that is inspired – but, critically, not confined – by its Chinese and British histories. The article briefly outlines the origins and set-up of the festival before juxtaposing the dominance of English language and culture in it with the opportunities it presents (seized by several teams) for intra-regional cooperation, competition and sharing diverse, greater Chinese cultures. The article offers a model for critically appraising other institutions and cultural products in Hong Kong in ways that resist easy binaries of British or Chinese, colonial or indigenous
Determination of Transgene Copy Number by Real-Time Quantitative PCR
Efficient methods to characterize transgenic plants are important to quickly understand the state of the transformant. Determining transgene copy number is an important step in transformant characterization and can differentiate between complex and simple transformation events. This knowledge can be extremely useful when determining what future experiments and uses the transgenic lines can be utilized for. The method described here uses real-time quantitative PCR to determine the transgene copy number present in the genome of the transformant. Specifically, this method measures the relative transgene copy number by comparing it with an endogenous gene with a known copy number. This method is a quick alternative to the Southern blot, a method that is commonly used to determine gene copy number, and is effective when screening large numbers of transformants
Sources of Sex Information Used by Young British Women Who Have Sex with Women (WSW) and Women Who Have Sex Exclusively with Men (WSEM): Evidence from the National Survey of Sexual Attitudes and Lifestyles
There is little consideration about the provision of information about sex to women who have sex with women (WSW). This study drew on data from the third National Survey of Sexual Attitudes and Lifestyle, a nationally representative survey of people in Great Britain. Logistic regression was undertaken to examine firstly the relationships between WSW and women who have sex exclusively with men (WSEM) and their main source of information about sex, and secondly between WSW/WSEM and unmet need for information about sex. Each source was included as the binary outcome indicating yes this was the main source, or no this was not the main source of information about sex. The results found that WSW had significantly lower odds of reporting lessons at schools as their main source of information, and significantly higher odds of reporting sources defined as ‘other’ (predominantly first girlfriend/boyfriend or sexual partner) as their main source of information. Reported levels of unmet need for information was also higher amongst young WSW compared with WSEM. This study provides new insights into the sex educational needs of young women and highlights the need for sex education in schools in Great Britain to include information on a full-range of sexual practices, including same-sex sexual relationships
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