1,691 research outputs found
Effective and safe lead extraction using the bidirectional rotational Evolution\uae sheath in a child with congenital heart disease
The Italian version of the Wong-Law Emotional Intelligence Scale (WLEIS-I): a second-order factor analysis
The Wong and Law Emotional Intelligence Scale (WLEIS) is a 16-item self-report measure of emotional intelligence, based on the revised model by Mayer and Salovey. The scale measures four dimensions: Self-Emotional Appraisal, Others' Emotion Appraisal, Use Of Emotion, Regulation Of Emotions, loading onto a higher-order emotional intelligence factor. The WLEIS has been translated and validated in several cultural contexts, but to date there is no Italian translation, and no studies investigated its factor structure in the Italian community. This study aimed at translating the WLEIS in Italian, analysing its psychometric properties in Italian adults from the community, and testing the fit between the data and the original model by Wong and Law. We also tested correlations between WLEIS and measures of the Big Five personality factors and attachment. We found that the scale was internally consistent, and the second-order factor solution fit the data well. We also found significant positive correlations with agreeableness, extraversion, and perception of the self and the others, and negative correlation with neuroticism. These results represent a preliminary attempt to study the application of the WLEIS in Italian community settings, with implications for assessment and intervention to enhance the subjective and psychological well-being of individuals
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Individual differences in interpersonal security predict suicidal ideation and problem gambling
Suicidality and problem gambling represent global health issues. Based on evidence from recent literature, the aim of the present study was to test a theoretical model, in which: (1) Emotional Intelligence and Self and Other Representations of adult attachment combine into a latent factor representing Interpersonal Security; (2) Interpersonal Security negatively predicts Problem Gambling and Suicidal Ideation, respectively; (3) Problem Gambling positively predicts Suicidal Ideation. We used Structural Equation Modelling to test the study hypotheses. The model showed good fit to the data. Factor loadings were high and statistically significant. We found that the hypothesis of Emotional Intelligence and Self and Other Representations combining into a common factor, Interpersonal Security, is empirically supported. The joint effect of Interpersonal Security and Problem Gambling explains about the 63% of variance of Suicidal ideation. The path from Interpersonal Security to Suicidal Ideation is significant and high, whilst the path from Problem Gambling to Suicidal Ideation is not significant. Interpersonal Security explains about 16% of the variance of Problem Gambling. These results outline an integrated model of Suicidal Ideation and Problem Gambling in the community from an interpersonal-psychological perspective, with important implications for researchers, mental health practitioners, and policymakers
Personality and suicidal ideation in the elderly: factorial invariance and latent means structures across age
Objectives: Suicide among the elderly is a dramatic global health problem. Although fatal attempts are frequent in the elderly, research indicated that they rarely present long-term elaboration of suicidal ideation and communicate their intents. Consequently, risk factor detection and assessment are salient. Although evidence on the association between personality and suicidal ideation in young adults is accumulating, little is known about its relevance in the elderly. The purpose of the present study was to analyze the components of a measurement model that are invariant across young adults and older adults and then investigate the relations among dimensions of personality and suicide risk. We postulated a specific relation pattern a priori and tested the hypotheses statistically in order to examine the models for equivalency of the factorial measurement.
Method: We investigated 316 young adults and 339 older adults, who were administered self-report questionnaires to assess depression, hopelessness, alternative five-factor model of personality, and self–other perception.
Results: Multigroup confirmatory factor analyses were conducted, yielding a final model with excellent fit to the data. This model showed a similar pattern of associations between suicidal ideation and personality across both groups.
Conclusions: Although the elderly are exposed to specific life stressors associated with suicidal ideation, our findings suggest that the elderly and young adults may be similar on personality and psychopathology variables predicting suicidal ideation than previously hypothesized. Implications are provided for enhanced assessment and intervention of the elderly high in neuroticism, depression, hopelessness, and with negative self–other perception
Prognostic impact of coronary microcirculation abnormalities in systemic sclerosis: a prospective study to evaluate the role of non-invasive tests
INTRODUCTION: Microcirculation dysfunction is a typical feature of systemic sclerosis (SSc) and represents the earliest abnormality of primary myocardial involvement. We assessed coronary microcirculation status by combining two functional tests in SSc patients and estimating its impact on disease outcome.
METHODS: Forty-one SSc patients, asymptomatic for coronary artery disease, were tested for coronary flow velocity reserve (CFR) by transthoracic-echo-Doppler with adenosine infusion (A-TTE) and for left ventricular wall motion abnormalities (WMA) by dobutamine stress echocardiography (DSE). Myocardial multi-detector computed tomography (MDCT) enabled the presence of epicardial stenosis, which could interfere with the accuracy of the tests, to be excluded. Patient survival rate was assessed over a 6.7- ± 3.5-year follow-up.
RESULTS: Nineteen out of 41 (46%) SSc patients had a reduced CFR (≤2.5) and in 16/41 (39%) a WMA was observed during DSE. Furthermore, 13/41 (32%) patients showed pathological CFR and WMA. An inverse correlation between wall motion score index (WMSI) during DSE and CFR value (r = -0.57, P <0.0001) was observed; in addition, CFR was significantly reduced (2.21 ± 0.38) in patients with WMA as compared to those without (2.94 ± 0.60) (P <0.0001). In 12 patients with abnormal DSE, MDCT was used to exclude macrovasculopathy. During a 6.7- ± 3.5-year follow-up seven patients with abnormal coronary functional tests died of disease-related causes, compared to only one patient with normal tests.
CONCLUSIONS: A-TTE and DSE tests are useful tools to detect non-invasively pre-clinical microcirculation abnormalities in SSc patients; moreover, abnormal CFR and WMA might be related to a worse disease outcome suggesting a prognostic value of these tests, similar to other myocardial diseases
Rest tremor in Parkinson's disease: body distribution and time of appearance
Objective To assess body distribution and timing of appearance of rest tremor in Parkinson's disease. Methods Information was obtained by a computerized database containing historical information collected at the first visit and data collected during the subsequent follow-up visits. Information on rest tremor developed during the follow-up could be therefore obtained by our own observation in a proportion of patients. Results Among 289 patients, rest tremor was reported at disease onset in 65.4% of cases and detected at last follow-up examination in 74.4% of patients. Analysis of patients who did not report rest tremor at disease onset indicated that 26% of such patients (9% in the overall population) manifested rest tremor over the disease course. Rest tremor spread to new sites in 39% of patients who manifested rest tremor at disease onset. Regardless of tremor presentation at disease onset or during the follow-up, upper limb was the most frequent tremor localization. Over the follow-up, rest tremor developed faster in the upper limb than in other body sites. The risk of developing rest tremor during the follow-up was not affected by sex, side of motor symptom onset and site of tremor presentation. However, age of disease onset > 63 years was associated with an increased risk of rest tremor spread. Conclusions This study provides new information about body distribution and timing of rest tremor appearance during the course of early stages of Parkinson's disease that may help clinicians in patients' counselling
Acute idiopathic pericarditis: current immunological theories
Alida LP Caforio,1 Renzo Marcolongo,2 Antonio Brucato,3 Luca Cantarini,4 Massimo Imazio,5 Sabino Iliceto11Division of Cardiology, Department of Cardiology, Thoracic and Vascular Sciences, University of Padua, Padua; 2Haematology and Clinical Immunology, Department of Medicine, University of Padua, Padua, 3Internal Medicine, Ospedali Riuniti, Bergamo, 4Rheumatology Unit, Policlinico Le Scotte, University of Siena, Siena, 5Department of Cardiology, Maria Vittoria Hospital, Torino, ItalyAbstract: Idiopathic recurrent acute pericarditis (IRAP) is a rare disease of suspected immune-mediated pathogenesis. It represents a diagnosis of exclusion. It is necessary to rule out infectious and noninfectious causes of pericardial inflammation, including systemic autoimmune and immune-related disorders, eg, Sjögren's disease, systemic lupus erythematosus. Since pericarditis may precede diagnosis of these disorders, IRAP diagnosis is often made after a long follow-up. According to the two main pathogenetic theories IRAP may represent an organ-specific autoimmune disease or an autoinflammatory disease (AInfD). The main evidence for autoimmunity in IRAP is provided by the detection of serum antiheart and antiintercalated-disk autoantibodies, and the response to anti-inflammatory or immunosuppressive therapy. The findings of familial forms and of proinflammatory cytokines in the pericardial fluid in IRAP would be in keeping with both organ-specific autoimmune disease and AInfD. In fact, AInfD are genetic disorders characterized by primary dysfunction of the innate immune system, due to mutations of genes involved in the regulation of the inflammatory response, in the absence of antigen specific T cells or autoantibodies. In AInfD there are active disease phases with raised non-cardiac specific inflammatory markers, such as C-reactive protein, as well as symptom-free intervals with possible C-reactive protein normalization. A minority of IRAP patients (6%) carry a mutation in the TNFRSF1A gene, encoding the receptor for tumor necrosis factor-alfa. This suggests that some IRAP patients may have an atypical or subclinical form of AInfD. Thus, IRAP may represent a syndrome with distinct pathogenetic mechanisms in different patients' subsets.Keywords: pericarditis, autoimmunity, autoantibodies, heart disease, immune factor
Hyperhomocysteinemia in L-dopa treated patients with Parkinson's disease: potential implications in cognitive dysfunction and dementia?
Abstract: Background: Hyperhomocysteinemia has been associated with cognitive dysfunction and dementia. The incidence
of dementia in Parkinson’s Disease (PD) patients is higher than in the general population and plasma Homocysteine
concentrations are increased in L-dopa treated PD patients.
Objective: We evaluated the possible correlations between L-Dopa related hyperhomocysteinemia and cognitive dysfunction
in PD.
Methods: A Medline literature search was performed to identify all published studies on Homocysteine and cognitive dysfunction
and dementia during the course of PD from 1966 to 31/03/2010.
Results: Sixteen studies were found for review; ten studies focused on homocysteine and cognitive dysfunction in PD patients,
five on homocysteine and PD dementia and two on homocysteine and markers of neurodegeneration in PD. The design
of the study was retrospective in 14 studies, while 2 had a prospective design, with a variable follow-up period (from
24-weeks to 2 years). In most of the studies plasma homocysteine levels significantly correlated with cognitive functions,
dementia and markers of neurodegeneration in PD patients. However, some studies did not confirm these findings. Several
factors may concur to explain these partially conflicting results, including the retrospective design of the studies, their
small sample size, their high percentage of excluded patients, and the use of a wide range of neuropsychological tasks in
assessment of cognitive dysfunctions across the available studies.
Conclusions: Available data seem to indicate a potential role of L-dopa related hyperhomocysteinemia on cognitive impairment
and dementia during the course of PD
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Do people have control over the decisions they make? Psychometric properties of the Italian version of the free will and scientific determinism questionnaire (FAD-plus-I)
The FAD-Plus is a multidimensional measure of lay Beliefs in Free Will, Fatalistic Determinism, Scientific Determinism, and Unpredictability. This study had four aims: First, to test the factor structure of the Italian translation of the FAD-Plus in a sample of adults from the community, using structural equation modeling. Second, to test the reliability of the four scales. Third, to investigate gender invariance in item thresholds and factor loadings. Fourth, to analyze the criterion-related validity of the measure. Participants were 328 adults from the community, specifically 173 females and 155 males aged 18–56 years. Results showed that the proposed bifactor model tested by means of exploratory structural equation modeling fitted the data well (CFI = 1.000, RMSEA = 0.000, SRMR = 0.045), and that all the scales were reliable (Omega = .91–.98). Gender invariance was established, with no significant differences in fit indices between females and males. Beliefs in Free Will correlated positively and lowly to moderately with Aggressiveness (rs = .12), Extraversion (.25), Self- (.40) and Other-Representations of adult attachment (.43). Beliefs in Fatalistic Determinism correlated positively and lowly with Other-Representations (rs = .11), whereas its correlations with Aggressiveness, Extraversion, and Neuroticism were close to zero. In conclusion, these findings provide researchers and practitioners with evidence on a reliable and valid measure of Beliefs in free will and determinism in the Italian context, considered as predictors of individuals’ autonomy, effective coping, and prosocial behavior, of foremost importance for prevention and intervention in the community, particularly in occupational, legal, and clinical settings
Dielectric, Switching and System Requirements under Out-of-Phase Conditions, during Synchronisation and under Comparable Stresses
Recent developments in electrical networks can increase the probability of out-of-phase switching and
dielectric stresses being applied to open circuit-breakers, due to asynchronous systems at both sides.
This report presents a systematic study of TRV-stresses associated with generator separation and
system separation. TRV peak values are higher than required in the Standards, even for relatively
small out-of-phase angles (75Âş to 90Âş), and the dielectric stresses are high with respect to the shortduration
power frequency withstand voltages across a circuit-breaker open contacts, especially taking
into consideration the external insulation under pollution and ageing processes. To the opinion of the
authors, the Standards should be revised to give users clear and adequate guidance on the assessment
and specification of TRV-values and dielectric withstand requirements under out-of-phase conditions
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