405 research outputs found
Thoracoscopic Surgical Treatment of Spontaneous Pneumothorax: Selection of Surgical Therapy According to Thoracoscopic Findings
We report our experience with thoracoscopy used for the treatment of spontaneous pneumothorax
and idiopathic emphysematous bullae. Fifty-one patients with pneumothorax were admitted to the
hospital and received a pleurography and CT scanning before thoracoscopy. End-GIA resection or
end-loop ligation were used alone or in combination, with or without laser coagulation. Only one patient
developed recurrent pneumothorax, whereas another required repeated resection. Our results
indicate that surgical treatment of pneumothorax using thoracoscopy results in a rapid expansion of
the lung, minimum postoperative pain, early hospital discharge, and return of normal activity
Nonpolar optical scattering of positronium in magnesium fluoride
We report the results of the analysis of the temperature broadening of the
momentum distribution of delocalized Positronium (Ps) in Magnesium Fluoride in
terms of optical deformation-potential scattering model (long-wavelength
optical phonons). The Ps optical deformation-potential coupling constant
in MgF has been determined to be eV/cm.
We also show that the Ps momentum distribution is sensitive to second-order
phase transitions in those crystals where optical deformation-potential
scattering is allowed in one and forbidden in another crystalline phase
Energy scalable terahertz-wave parametric oscillator using surface-emitted configuration
We experimentally demonstrated the scalability of the terahertz-wave parametric oscillator by using a pump beam with a wide aperture and a high pulse energy. Terahertz-wave absorption by the LiNbO3 crystal in the oscillator is substantially suppressed by employing a surface-emitting cavity configuration. We also improved the conversion efficiency by increasing the parametric interaction in the noncollinear phase-matching geometry. A pump depletion of 54% and a conversion efficiency of 0.9 × 10-6 are achieved. A maximum terahertz output of 382 nJ/pulse was achieved at 1.46 THz using a 8.0-mm-diameter pump beam with a pulse energy of 465 mJ/pulse
Terahertz analysis of an East Asian historical mural painting
Terahertz (THz) spectroscopy and THz and imaging techniques are expected to have great potential for the non-invasive analysis of artworks. We have applied THz imaging to analyse the historic mural painting of a Lamaism temple by using a transportable time-domain THz imaging system; such an attempt is the first in the world. The reflection image revealed that there are two orange colours in the painting, although they appear the same to the naked eye. THz imaging can also estimate the depth of cracks. The colours were examined by X-ray fluorescence and Raman spectroscopy, and the results were found to be in good agreement. This work proved that THz imaging can contribute to the non-invasive analysis of cultural heritage
Study of the plutino object (208996) 2003 AZ84 from stellar occultations: size, shape and topographic features
We present results derived from four stellar occultations by the plutino
object (208996) 2003~AZ, detected at January 8, 2011 (single-chord
event), February 3, 2012 (multi-chord), December 2, 2013 (single-chord) and
November 15, 2014 (multi-chord). Our observations rule out an oblate spheroid
solution for 2003~AZ's shape. Instead, assuming hydrostatic equilibrium,
we find that a Jacobi triaxial solution with semi axes ~km % axis ratios and
, can better account for all our occultation observations.
Combining these dimensions with the rotation period of the body (6.75~h) and
the amplitude of its rotation light curve, we derive a density ~g~cm a geometric albedo . A grazing chord
observed during the 2014 occultation reveals a topographic feature along
2003~AZ's limb, that can be interpreted as an abrupt chasm of width
~km and depth ~km or a smooth depression of width ~km
and depth ~km (or an intermediate feature between those two extremes)
CVIT expert consensus document on primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) in 2018
While primary percutaneous coronary intervention (PCI) has significantly contributed to improve the mortality in patients with ST segment elevation myocardial infarction even in cardiogenic shock, primary PCI is a standard of care in most of Japanese institutions. Whereas there are high numbers of available facilities providing primary PCI in Japan, there are no clear guidelines focusing on procedural aspect of the standardized care. Whilst updated guidelines for the management of acute myocardial infarction were recently published by European Society of Cardiology, the following major changes are indicated; (1) radial access and drug-eluting stent over bare metal stent were recommended as Class I indication, and (2) complete revascularization before hospital discharge (either immediate or staged) is now considered as Class IIa recommendation. Although the primary PCI is consistently recommended in recent and previous guidelines, the device lag from Europe, the frequent usage of coronary imaging modalities in Japan, and the difference in available medical therapy or mechanical support may prevent direct application of European guidelines to Japanese population. The Task Force on Primary Percutaneous Coronary Intervention of the Japanese Association of Cardiovascular Intervention and Therapeutics (CVIT) has now proposed the expert consensus document for the management of acute myocardial infarction focusing on procedural aspect of primary PCI
Report and preliminary results of R/V SONNE Cruise SO251 - Extreme events Archived in the GEologial Record of JAPAN's subduction margins (EAGER-JAPAN)
Leg A SO251-1, Yokohama - Yokohama, 04.10.2016 - 15.10.2016, Leg B SO251-2, Yokohama - Yokohama, 18.10.2016 - 02.11.201
Current status of space gravitational wave antenna DECIGO and B-DECIGO
Deci-hertz Interferometer Gravitational Wave Observatory (DECIGO) is the future Japanese space mission with a frequency band of 0.1 Hz to 10 Hz. DECIGO aims at the detection of primordial gravitational waves, which could be produced during the inflationary period right after the birth of the universe. There are many other scientific objectives of DECIGO, including the direct measurement of the acceleration of the expansion of the universe, and reliable and accurate predictions of the timing and locations of neutron star/black hole binary coalescences. DECIGO consists of four clusters of observatories placed in the heliocentric orbit. Each cluster consists of three spacecraft, which form three Fabry-Perot Michelson interferometers with an arm length of 1,000 km. Three clusters of DECIGO will be placed far from each other, and the fourth cluster will be placed in the same position as one of the three clusters to obtain the correlation signals for the detection of the primordial gravitational waves. We plan to launch B-DECIGO, which is a scientific pathfinder of DECIGO, before DECIGO in the 2030s to demonstrate the technologies required for DECIGO, as well as to obtain fruitful scientific results to further expand the multi-messenger astronomy
Time-averaged disease activity fits better joint destruction in rheumatoid arthritis
Pathophysiology and treatment of rheumatic disease
Chemotherapy with cisplatin and vinorelbine for elderly patients with locally advanced or metastatic non-small-cell lung cancer (NSCLC)
BACKGROUND: Although modest improvements in the survival of patients with non-small cell lung cancer (NSCLC) can be achieved with cisplatin-based chemotherapy (CT), its value is disputed in the geriatric setting. In this study, we evaluate the feasibility of vinorelbine/cisplatin CT for elderly NSCLC patients. METHODS: In this pilot phase I/II trial, all patients received CT with vinorelbine 25 mg/m(2), on day 1 and 8, and cisplatin on day 1, in 28 days-cycles. After stratification for age (up to 75 years), younger patients were sequentially allocated to moderate cisplatin doses (80 mg/m(2 )or 90 mg/m(2)), and older patients were allocated to lower cisplatin doses (60 mg/m(2 )or 70 mg/m(2)). We recruited patients aged over 70 years with newly diagnosed NSCLC, clinical stage III or IV, Karnofsky performance status ≥ 70%, normal serum creatinine, peripheral neuropathy ≤ grade 1, and no prior cancer therapy. RESULTS: Analysis was by intention to treat. Main toxicities (grade 3–4) was as follows: neutropenia, 20%; anemia, 11%; and thrombocytopenia, 2%; alopecia, 55%; fatigue, 11%; and peripheral neurotoxicity, 2%. No grade 3–4 emesis or renal toxicity occurred. Global median time to progression (TTP) and overall survival (OS) were 27.0 (95% CI: 10.1 to 43.7) weeks and 30.1 (95% CI: 24.4 to 35.8) weeks; 1- and 2-year survival rates were 36.3% and 13.2%, respectively. Overall response rate was 50.0% (95% CI: 35.4% to 64.5%), with 1 complete response; no difference on response rate was noticed according to cisplatin dose. Median overall survival was 30.1 weeks, with 1- and 2-year survival rates of 36.3% and 13.2%, respectively. CONCLUSION: Age does not preclude assessment on the role of cisplatin-vinorelbine CT for elderly NSCLC patients with good performance status and adequate bodily functions
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