3,213 research outputs found
Government budgets and the promotion of gender equality in Japan and South Korea
노트 : Paper presented to the IAFFE panel of the Society of Heterodox Economics Conference University of New South Wales, Sydney, December 2-3, 201
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Monitoring kidney optical properties during cold storage preservation with spatial frequency domain imaging.
Transplantation of kidneys results in delayed graft function in as many as 40% of cases. During the organ transplantation process, donor kidneys undergo a period of cold ischemic time (CIT), where the organ is preserved with a cold storage solution to maintain tissue viability. Some complications observed after grafting may be due to damage sustained to the kidney during CIT. However, the effects due to this damage are not apparent until well after transplant surgery has concluded. To this end, we have used spatial frequency domain imaging (SFDI) to measure spatially resolved optical properties of porcine kidneys over the course of 80-h CIT. During this time, we observed an increase in both reduced scattering (μs&') and absorption (μa) coefficients. The measured scattering b parameter increased until 24 h of CIT, then returned toward baseline during the remaining duration of the imaging sequence. These results show that the optical properties of kidney tissue change with increasing CIT and suggest that continued investigation into the application of SFDI to kidneys under CIT may lead to the development of a noninvasive method for assessing graft viability
Relativistic Hartree approach with exact treatment of vacuum polarization for finite nuclei
We study the relativistic Hartree approach with the exact treatment of the
vacuum polarization in the Walecka sigma-omega model. The contribution from the
vacuum polarization of nucleon-antinucleon field to the source term of the
meson fields is evaluated by performing the energy integrals of the Dirac Green
function along the imaginary axis. With the present method of the vacuum
polarization in finite system, the total binding energies and charge radii of
16O and 40Ca can be reproduced. On the other hand, the level-splittings in the
single-particle level, in particular the spin-orbit splittings, are not
described nicely because the inclusion of vacuum effect provides a large
effective mass with small meson fields. We also show that the derivative
expansion of the effective action which has been used to calculate the vacuum
contribution for finite nuclei gives a fairly good approximation.Comment: 15 pages, 8 figure
Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-inflammatory Pathways.
Oxidative stress and chronic inflammation play critical roles in the pathogenesis of ulcerative colitis (UC) and inflammatory bowel diseases (IBD). A previous study has demonstrated that dimethyl fumarate (DMF) protects mice from dextran sulfate sodium (DSS)-induced colitis via its potential antioxidant capacity, and by inhibiting the activation of the NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome. This study aims to clarify the nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) pathway pharmacological activation and anti-inflammatory effect by DMF, through focusing on other crucial antioxidant enzymes and inflammatory mediator, including glutamate-cysteine ligase catalytic subunit (GCLC), glutathione peroxidase (GPX) and cyclooxygenase-2 (COX-2), in a DSS-induced colitis mouse model. The oral administration of DMF attenuated the shortening of colons and alleviated colonic inflammation. Furthermore, the expression of key antioxidant enzymes, including GCLC and GPX, in the colonic tissue were significantly increased by DMF administration. In addition, protein expression of the inflammatory mediator, COX-2, was reduced by DMF administration. Our results suggest that DMF alleviates DSS-induced colonic inflammatory damage, likely via up-regulating GCLC and GPX and down-regulating COX-2 protein expression in colonic tissue
小規模行政区域内の地震時緊急救援道路の検討のための簡易な枠組み
The number of deaths related to earthquake disasters might depend on the speed with which people receive medical treatment during emergencies. The rapid transportation of injured people to the closest hospital is important for decreasing the number of fatalities, and the road networks used by emergency transportation vehicles during disasters are key to disaster mitigation. This study proposed a simple framework to be used in discussions of the performance of emergency transportation routes in small townships in developing countries. The framework comprises an estimation method for road damages and connectivity of the road network to hospitals. Although the details of this damage estimation method were not fully examined, a feasibility study of the proposed framework was conducted on small townships in Mandalay, Myanmar. The results found that the proposed framework is simple, but effective for predicting future aspects of disaster mitigation, particularly in developing countries where precise data are not available or not reliable
Relativistic Two-Body Processes in Axial-Charge Transitions
We study the contribution of two-body meson-exchange processes to axial
charge transitions for nuclei in the lead, tin and oxygen regions. We conduct
calculations in the Dirac-Hartree (the Walecka model) and the relativistic
Hartree (where the full one-nucleon-loop effects are included) approximations.
We present results indicating that one- and two-body processes enhance the
matrix elements of the axial-charge operator by some (100+-20)% in all three
regions studied. This agrees well with the fit of eighteen first-forbidden
beta-decay transitions conducted by Warburton in the lead region. We also
discuss some sensitivities present in the calculation.Comment: 23 pages, RevTeX format, 5 PostScript figures available on reques
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